PMID- 28539544
OWN - NLM
STAT- MEDLINE
DCOM- 20171212
LR  - 20181113
IS  - 2186-1005 (Electronic)
IS  - 1341-1098 (Print)
IS  - 1341-1098 (Linking)
VI  - 23
IP  - 4
DP  - 2017 Aug 20
TI  - Postoperative Outcome of High-Risk Octogenarians Undergoing Cardiac Surgery: A 
      Multicenter Observational Retrospective Study.
PG  - 188-195
LID - 10.5761/atcs.oa.16-00280 [doi]
AB  - PURPOSE: Cardiac surgery in octogenarians with severely deteriorated functional 
      status is increasingly common, but outcome data are still limited. The aim of 
      this study was to compare postoperative outcome, survival, and quality of life of 
      low-, medium-, and high-risk octogenarians undergoing cardiac surgery. METHODS: 
      In all, 285 Czech octogenarians who underwent any cardiac surgical procedure 
      between January 2011 and December 2012 were included in the study. Five out of 
      all twelve national adult cardiac surgical centers participated in the study, 
      representing almost half of all octogenarians operated in our country in that 
      period. Patients' perioperative data were analyzed retrospectively. Follow-up was 
      performed by interviewing patients by telephone. RESULTS: There was higher 30-day 
      mortality (20% vs. 6.4% vs. 5.2%, respectively, p <0.001), lower 2-year survival 
      (60% vs. 84.0% vs. 85.4%, respectively, p <0.05), and lower Karnofsky score (44.4 
      vs. 70.1 vs. 70.6, respectively, p <0.001) in high-risk group compared with 
      medium- and low-risk groups, respectively. Greater improvement in New York Heart 
      Association (NYHA) status was noted in high- and medium-risk groups compared with 
      low-risk group (51% vs. 45% vs. 24%, respectively, p <0.05). CONCLUSION: High 
      perioperative mortality, poor 2-year survival, and low postoperative quality of 
      life have been observed in high-risk octogenarians undergoing cardiac surgery.
FAU - Porizka, Michal
AU  - Porizka M
AD  - General University Hospital, Department of Anaesthesiology, Resuscitation and 
      Intensive Medicine, The First Faculty of Medicine, Charles University in Prague, 
      Prague, Czech Republic.
FAU - Kunstyr, Jan
AU  - Kunstyr J
AD  - General University Hospital, Department of Anaesthesiology, Resuscitation and 
      Intensive Medicine, The First Faculty of Medicine, Charles University in Prague, 
      Prague, Czech Republic.
FAU - Vanek, Tomas
AU  - Vanek T
AD  - University Hospital Kralovske Vinohrady, Department of Cardiac Surgery, Third 
      Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
FAU - Nejedly, Michal
AU  - Nejedly M
AD  - University Hospital Kralovske Vinohrady, Department of Cardiac Surgery, Third 
      Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
FAU - Buckova, Jana
AU  - Buckova J
AD  - Na Homolce Hospital, Department of Cardiology, Prague, Czech Republic.
FAU - Mokrejs, Jiri
AU  - Mokrejs J
AD  - Faculty Hospital Pilsen, Department of Cardiac Surgery, Charles University in 
      Prague, Pilsen-Bory, Czech Republic.
FAU - Mosna, Frantisek
AU  - Mosna F
AD  - Motol University Hospital, Department of Anaesthesiology and Intensive Care 
      Medicine, The Second Faculty of Medicine, Charles University in Prague, Prague, 
      Czech Republic.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Multicenter Study
PT  - Observational Study
DEP - 20170524
PL  - Japan
TA  - Ann Thorac Cardiovasc Surg
JT  - Annals of thoracic and cardiovascular surgery : official journal of the 
      Association of Thoracic and Cardiovascular Surgeons of Asia
JID - 9703158
SB  - IM
MH  - Age Factors
MH  - Aged, 80 and over
MH  - Cardiac Surgical Procedures/*adverse effects/mortality
MH  - Czech Republic
MH  - Female
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Karnofsky Performance Status
MH  - Male
MH  - Postoperative Complications/diagnosis/*etiology/mortality/therapy
MH  - Proportional Hazards Models
MH  - Quality of Life
MH  - Retrospective Studies
MH  - Risk Assessment
MH  - Risk Factors
MH  - Time Factors
MH  - Treatment Outcome
PMC - PMC5569253
OTO - NOTNLM
OT  - cardiac surgery
OT  - mortality
OT  - octogenarians
OT  - postoperative outcome
OT  - quality of life
EDAT- 2017/05/26 06:00
MHDA- 2017/12/13 06:00
PMCR- 2017/01/01
CRDT- 2017/05/26 06:00
PHST- 2017/05/26 06:00 [pubmed]
PHST- 2017/12/13 06:00 [medline]
PHST- 2017/05/26 06:00 [entrez]
PHST- 2017/01/01 00:00 [pmc-release]
AID - atcs.oa.16-00280 [pii]
AID - 10.5761/atcs.oa.16-00280 [doi]
PST - ppublish
SO  - Ann Thorac Cardiovasc Surg. 2017 Aug 20;23(4):188-195. doi: 
      10.5761/atcs.oa.16-00280. Epub 2017 May 24.