PMID- 28540634
OWN - NLM
STAT- MEDLINE
DCOM- 20190610
LR  - 20190613
IS  - 1868-4297 (Electronic)
IS  - 1868-4297 (Linking)
VI  - 33
IP  - 3
DP  - 2018 Jul
TI  - Simplifying contrast-induced acute kidney injury prediction after primary 
      percutaneous coronary intervention: the age, creatinine and ejection fraction 
      score.
PG  - 224-231
LID - 10.1007/s12928-017-0472-y [doi]
AB  - Contrast-induced acute kidney injury (CI-AKI) is a common event after 
      percutaneous coronary intervention (PCI). Presently, the main strategy to avoid 
      CI-AKI lies in saline hydration, since to date none pharmacologic prophylaxis 
      proved beneficial. Our aim was to determine if a low complexity mortality risk 
      model is able to predict CI-AKI in patients undergoing PCI after ST elevation 
      myocardial infarction (STEMI). We have included patients with STEMI submitted to 
      primary PCI in a tertiary hospital. The definition of CI-AKI was a raise of 
      0.3 mg/dL or 50% in post procedure (24-72 h) serum creatinine compared to 
      baseline. Age, glomerular filtration and ejection fraction were used to calculate 
      ACEF-MDRD score. We have included 347 patients with mean age of 60 years. In 
      univariate analysis, age, diabetes, previous ASA use, Killip 3 or 4 at admission, 
      ACEF-MDRD and Mehran scores were predictors of CI-AKI. After multivariate 
      adjustment, only ACEF-MDRD score and diabetes remained CI-AKI predictors. Areas 
      under the ROC curve of ACEF-MDRD and Mehran scores were 0.733 (0.68-0.78) and 
      0.649 (0.59-0.70), respectively. When we compared both scores with DeLong test 
      ACEF-MDRDs AUC was greater than Mehran's (P = 0.03). An ACEF-MDRD score of 2.33 
      or lower has a negative predictive value of 92.6% for development of CI-AKI. 
      ACEF-MDRD score is a user-friendly tool that has an excellent CI-AKI predictive 
      accuracy in patients undergoing primary percutaneous coronary intervention. 
      Moreover, a low ACEF-MDRD score has a very good negative predictive value for 
      CI-AKI, which makes this complication unlikely in patients with an ACEF-MDRD 
      score of <2.33.
FAU - Araujo, Gustavo N
AU  - Araujo GN
AD  - Cardiology Service, Hospital de Clinicas de Porto Alegre, Ramiro Barcelos 2350, 
      Porto Alegre, RS, 90035-003, Brazil. gustavon.araujo@gmail.com.
AD  - School of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, 
      Brazil. gustavon.araujo@gmail.com.
FAU - Pivatto Junior, Fernando
AU  - Pivatto Junior F
AD  - Cardiology Service, Hospital de Clinicas de Porto Alegre, Ramiro Barcelos 2350, 
      Porto Alegre, RS, 90035-003, Brazil.
FAU - Fuhr, Bruno
AU  - Fuhr B
AD  - Cardiology Service, Hospital de Clinicas de Porto Alegre, Ramiro Barcelos 2350, 
      Porto Alegre, RS, 90035-003, Brazil.
AD  - School of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, 
      Brazil.
FAU - Cassol, Elvis P
AU  - Cassol EP
AD  - Cardiology Service, Hospital de Clinicas de Porto Alegre, Ramiro Barcelos 2350, 
      Porto Alegre, RS, 90035-003, Brazil.
AD  - School of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, 
      Brazil.
FAU - Machado, Guilherme P
AU  - Machado GP
AD  - Cardiology Service, Hospital de Clinicas de Porto Alegre, Ramiro Barcelos 2350, 
      Porto Alegre, RS, 90035-003, Brazil.
AD  - School of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, 
      Brazil.
FAU - Valle, Felipe H
AU  - Valle FH
AD  - Cardiology Service, Hospital de Clinicas de Porto Alegre, Ramiro Barcelos 2350, 
      Porto Alegre, RS, 90035-003, Brazil.
AD  - School of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, 
      Brazil.
FAU - Bergoli, Luiz C
AU  - Bergoli LC
AD  - Cardiology Service, Hospital de Clinicas de Porto Alegre, Ramiro Barcelos 2350, 
      Porto Alegre, RS, 90035-003, Brazil.
FAU - Wainstein, Rodrigo V
AU  - Wainstein RV
AD  - Cardiology Service, Hospital de Clinicas de Porto Alegre, Ramiro Barcelos 2350, 
      Porto Alegre, RS, 90035-003, Brazil.
FAU - Polanczyk, Carisi A
AU  - Polanczyk CA
AD  - Cardiology Service, Hospital de Clinicas de Porto Alegre, Ramiro Barcelos 2350, 
      Porto Alegre, RS, 90035-003, Brazil.
AD  - School of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, 
      Brazil.
FAU - Wainstein, Marco V
AU  - Wainstein MV
AD  - Cardiology Service, Hospital de Clinicas de Porto Alegre, Ramiro Barcelos 2350, 
      Porto Alegre, RS, 90035-003, Brazil.
AD  - School of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, 
      Brazil.
LA  - eng
PT  - Journal Article
DEP - 20170524
PL  - Japan
TA  - Cardiovasc Interv Ther
JT  - Cardiovascular intervention and therapeutics
JID - 101522043
RN  - 0 (Contrast Media)
RN  - AYI8EX34EU (Creatinine)
SB  - IM
MH  - Acute Kidney Injury/*chemically induced/diagnosis
MH  - Age Factors
MH  - Aged
MH  - Brazil
MH  - Contrast Media/*adverse effects
MH  - Creatinine/blood
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Percutaneous Coronary Intervention/*adverse effects/methods
MH  - ROC Curve
MH  - Registries
MH  - Retrospective Studies
MH  - Risk Assessment/*methods
MH  - Risk Factors
MH  - ST Elevation Myocardial Infarction/*surgery
MH  - Stroke Volume/physiology
OTO - NOTNLM
OT  - Acute myocardial infarction
OT  - Contrast-induced acute kidney injury
OT  - Prediction models
OT  - Primary percutaneous coronary intervention
EDAT- 2017/05/26 06:00
MHDA- 2019/06/14 06:00
CRDT- 2017/05/26 06:00
PHST- 2017/03/26 00:00 [received]
PHST- 2017/05/17 00:00 [accepted]
PHST- 2017/05/26 06:00 [pubmed]
PHST- 2019/06/14 06:00 [medline]
PHST- 2017/05/26 06:00 [entrez]
AID - 10.1007/s12928-017-0472-y [pii]
AID - 10.1007/s12928-017-0472-y [doi]
PST - ppublish
SO  - Cardiovasc Interv Ther. 2018 Jul;33(3):224-231. doi: 10.1007/s12928-017-0472-y. 
      Epub 2017 May 24.