PMID- 28547533
OWN - NLM
STAT- MEDLINE
DCOM- 20180717
LR  - 20220409
IS  - 1573-2630 (Electronic)
IS  - 0165-5701 (Linking)
VI  - 38
IP  - 3
DP  - 2018 Jun
TI  - Sensitivity and specificity of optical coherence tomography angiography (OCT-A) 
      for detection of choroidal neovascularization in real-life practice and varying 
      retinal expertise level.
PG  - 1051-1060
LID - 10.1007/s10792-017-0559-6 [doi]
AB  - PURPOSE: To evaluate the diagnostic accuracy of OCT angiography (OCT-A) detecting 
      or predicting choroidal neovascularization (CNV), by ophthalmologists of 
      disparate degrees of skills in retinal diseases, using spectral domain optical 
      coherence tomography (SD-OCT) and fluorescein angiography (FA) as a standard 
      reference. METHODS: Retrospective observational case series. Patient presenting 
      maculopathy and complete imaging were included. FA, SD-OCT, OCT-A and FA coupled 
      to SD-OCT images were graded independently for presence or absence of CNV by 
      ophthalmologists with varying expertise levels. RESULTS: Overall sensitivity of 
      OCT-A was 85.62% (95% CI 79.04-90.76%) and specificity was 81.51% (95% CI 
      73.36-88.03). Sensitivity of FA was 74.51% (95% CI 66.84-81.20), and specificity 
      was 82.35% (95% CI 74.30-88.73). Sensitivity of FA + SD-OCT was 92.72% (95% CI 
      87.34-96.30), and specificity was 90.91% (95% CI 84.31-95.37). CONCLUSION: OCT-A 
      has good sensitivity and specificity for the detection of CNV in all expertise 
      level groups. OCT-A may soon become a routine tool for CNV diagnosis and 
      follow-up.
FAU - Souedan, Vael
AU  - Souedan V
AD  - Department of Ophthalmology, Creteil University Eye Clinic, Hopital Intercommunal 
      de Creteil, University Paris Est, 40 Avenue de Verdun, 94010, Creteil, France.
FAU - Souied, Eric H
AU  - Souied EH
AD  - Department of Ophthalmology, Creteil University Eye Clinic, Hopital Intercommunal 
      de Creteil, University Paris Est, 40 Avenue de Verdun, 94010, Creteil, France.
FAU - Caillaux, Violaine
AU  - Caillaux V
AD  - Department of Ophthalmology, Creteil University Eye Clinic, Hopital Intercommunal 
      de Creteil, University Paris Est, 40 Avenue de Verdun, 94010, Creteil, France.
FAU - Miere, Alexandra
AU  - Miere A
AD  - Department of Ophthalmology, Creteil University Eye Clinic, Hopital Intercommunal 
      de Creteil, University Paris Est, 40 Avenue de Verdun, 94010, Creteil, France.
FAU - Ameen, Ala El
AU  - Ameen AE
AD  - Department of Ophthalmology, Creteil University Eye Clinic, Hopital Intercommunal 
      de Creteil, University Paris Est, 40 Avenue de Verdun, 94010, Creteil, France.
FAU - Blanco-Garavito, Rocio
AU  - Blanco-Garavito R
AD  - Department of Ophthalmology, Creteil University Eye Clinic, Hopital Intercommunal 
      de Creteil, University Paris Est, 40 Avenue de Verdun, 94010, Creteil, France. 
      rocio_blancog@hotmail.com.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20170525
PL  - Netherlands
TA  - Int Ophthalmol
JT  - International ophthalmology
JID - 7904294
SB  - IM
MH  - Aged
MH  - Choroidal Neovascularization/*diagnosis
MH  - Clinical Coding
MH  - *Clinical Competence
MH  - Female
MH  - Fluorescein Angiography/*methods
MH  - Fundus Oculi
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Ophthalmologists/*standards
MH  - Retrospective Studies
MH  - Sensitivity and Specificity
MH  - Tomography, Optical Coherence/*methods
MH  - Visual Acuity
OTO - NOTNLM
OT  - Choroidal neovascularization detection
OT  - Exudative AMD
OT  - Optical coherence tomography angiography
OT  - Sensitivity
OT  - Specificity
EDAT- 2017/05/27 06:00
MHDA- 2018/07/18 06:00
CRDT- 2017/05/27 06:00
PHST- 2016/12/25 00:00 [received]
PHST- 2017/05/10 00:00 [accepted]
PHST- 2017/05/27 06:00 [pubmed]
PHST- 2018/07/18 06:00 [medline]
PHST- 2017/05/27 06:00 [entrez]
AID - 10.1007/s10792-017-0559-6 [pii]
AID - 10.1007/s10792-017-0559-6 [doi]
PST - ppublish
SO  - Int Ophthalmol. 2018 Jun;38(3):1051-1060. doi: 10.1007/s10792-017-0559-6. Epub 
      2017 May 25.