PMID- 28548313 OWN - NLM STAT- MEDLINE DCOM- 20181015 LR - 20191210 IS - 1365-2753 (Electronic) IS - 1356-1294 (Linking) VI - 23 IP - 6 DP - 2017 Dec TI - Total knee replacement: Are there any baseline factors that have influence in patient reported outcomes? PG - 1232-1239 LID - 10.1111/jep.12765 [doi] AB - BACKGROUND: There is conflicting evidence about what factors influence outcomes after total knee replacement (TKR). The objective is to identify baseline factors that differentiate patients who achieve both, minimal clinically important difference (MCID) and a patient acceptable symptom state (PASS) in pain and function, measured by WOMAC, after TKR from those who do not attain scores above the cutoff in either of these dimensions. METHODS: One-year prospective multicentre study. Patients completed WOMAC, SF-12, EQ-5D, expectations, other joint problems and sociodemographic data while in the waiting list, and 1-year post-TKR. Dependent variable was a combination of MCID and PASS in both dimensions (yes/no). Univariate analysis was performed to identify variables associated. Exploratory factor analysis (EFA) was performed to study how these variables grouped into different factors. RESULTS: Total sample comprised 492 patients. Mean (SD) age was 71.3 (6.9), and there were a 69.7% of women. Of the total, 106 patients did not attain either MCID or PASS in either dimension, and 230 exceeded both thresholds in both dimensions. In the univariate analysis, 13 variables were associated with belonging to one group or another. These 13 variables were included in EFA; 3 factors were extracted: expectations, mental health, and other joints problems. The percentage of variance explained by the 3 factors was 80.4%. CONCLUSION: We have found 2 modifiable baseline factors, expectations and mental health, that should be properly managed by different specialist. Indication of TKR should take into account these modifiable factors for improving outcomes after TKR. CI - (c) 2017 John Wiley & Sons, Ltd. FAU - Escobar, A AU - Escobar A AUID- ORCID: 0000-0001-6566-3006 AD - Research Unit, Hospital Universitario Basurto, Bilbao, Spain. AD - Research Associate, Red de Investigacion en Servicios Sanitarios en Enfermedades Cronicas (REDISSEC), Spain. FAU - Garcia Perez, L AU - Garcia Perez L AD - Planning and Evaluation Service, Canary Islands Health Service, Tenerife, Spain. AD - Research Associate, Red de Investigacion en Servicios Sanitarios en Enfermedades Cronicas (REDISSEC), Spain. FAU - Herrera-Espineira, C AU - Herrera-Espineira C AD - Hospital Virgen de las Nieves, Granada, Spain. AD - Research Associate, Red de Investigacion en Servicios Sanitarios en Enfermedades Cronicas (REDISSEC), Spain. FAU - Aizpuru, F AU - Aizpuru F AD - Research Unit, Hospital Universitario Araba, Vitoria-Gasteiz, Spain. AD - Research Associate, Red de Investigacion en Servicios Sanitarios en Enfermedades Cronicas (REDISSEC), Spain. FAU - Sarasqueta, C AU - Sarasqueta C AD - Research Unit, Hospital Universitario Donostia, San Sebastian, Spain. AD - Research Associate, Red de Investigacion en Servicios Sanitarios en Enfermedades Cronicas (REDISSEC), Spain. FAU - Gonzalez Saenz de Tejada, M AU - Gonzalez Saenz de Tejada M AD - Research Unit, Hospital Universitario Basurto, Bilbao, Spain. AD - Research Associate, Red de Investigacion en Servicios Sanitarios en Enfermedades Cronicas (REDISSEC), Spain. FAU - Quintana, J M AU - Quintana JM AD - Research Unit, Hospital of Galdakao-Usansolo, Galdakao, Spain. AD - Research Associate, Red de Investigacion en Servicios Sanitarios en Enfermedades Cronicas (REDISSEC), Spain. FAU - Bilbao, A AU - Bilbao A AD - Research Unit, Hospital Universitario Basurto, Bilbao, Spain. AD - Research Associate, Red de Investigacion en Servicios Sanitarios en Enfermedades Cronicas (REDISSEC), Spain. LA - eng PT - Journal Article PT - Multicenter Study PT - Observational Study DEP - 20170526 PL - England TA - J Eval Clin Pract JT - Journal of evaluation in clinical practice JID - 9609066 SB - IM MH - Aged MH - Aged, 80 and over MH - Arthroplasty, Replacement, Knee/*psychology MH - Female MH - Humans MH - Male MH - Mental Health MH - Middle Aged MH - Outcome Assessment, Health Care MH - *Patient Reported Outcome Measures MH - *Patient Satisfaction MH - Prospective Studies MH - Quality of Life MH - Severity of Illness Index MH - Socioeconomic Factors OTO - NOTNLM OT - MCID OT - PASS OT - baseline factors OT - outcomes OT - total knee replacement EDAT- 2017/05/27 06:00 MHDA- 2018/10/16 06:00 CRDT- 2017/05/27 06:00 PHST- 2016/09/13 00:00 [received] PHST- 2017/04/07 00:00 [revised] PHST- 2017/04/07 00:00 [accepted] PHST- 2017/05/27 06:00 [pubmed] PHST- 2018/10/16 06:00 [medline] PHST- 2017/05/27 06:00 [entrez] AID - 10.1111/jep.12765 [doi] PST - ppublish SO - J Eval Clin Pract. 2017 Dec;23(6):1232-1239. doi: 10.1111/jep.12765. Epub 2017 May 26.