PMID- 28548864
OWN - NLM
STAT- MEDLINE
DCOM- 20180514
LR  - 20180514
IS  - 1466-1799 (Electronic)
IS  - 0007-1668 (Linking)
VI  - 58
IP  - 5
DP  - 2017 Oct
TI  - Oral administration of a medium containing both D-aspartate-producing live 
      bacteria and D-aspartate reduces rectal temperature in chicks.
PG  - 569-577
LID - 10.1080/00071668.2017.1335858 [doi]
AB  - 1. The aim of this study was to investigate the effects on the rectal temperature 
      of young chicks of the oral administration of a medium that contained both live 
      bacteria that produce D-aspartate (D-Asp) and D-Asp. 2. In Experiment 1, chicks 
      were subjected to chronic oral administration of either the medium (containing 
      live bacteria and 2.46 mumol D-Asp) or water from 7 to 14 d of age. Plasma-free 
      amino acids as well as mitochondrial biogenic gene expression in the breast 
      muscle were analysed. In Experiment 2, 7-d-old chicks were subjected to acute 
      oral administration of the above medium or of an equimolar amount of D-Asp to 
      examine their effect on changes in rectal temperature. In Experiment 3, after 
      1 week of chronic oral administration of the medium, 14-d-old chicks were exposed 
      to either high ambient temperature (HT; 40 +/- 1 degrees C, 3 h) or control thermoneutral 
      temperature (CT; 30 +/- 1 degrees C, 3 h) to monitor the changes in rectal temperature. 3. 
      Chronic, but not acute, oral administration of the medium significantly reduced 
      rectal temperature in chicks, and a chronic effect also appeared under HT 
      conditions. 4. Chronic oral administration of the medium significantly reduced 
      the mRNA abundance of the avian uncoupling protein (avUCP) in the breast muscle, 
      but led to a significant increase in avian adenine nucleotide translocator 
      (avANT) mRNA in the same muscle. 5. (a) These results indicate that the medium 
      can reduce body temperature through the decline in avUCP mRNA expression in the 
      breast muscle that may be involved in reduced mitochondrial proton leaks and heat 
      production. (b) The increase in avANT further suggests a possible enhancement of 
      adenosine triphosphate (ATP) synthesis.
FAU - Do, P H
AU  - Do PH
AD  - a Laboratory of Regulation in Metabolism and Behavior , Graduate School of 
      Bioresource and Bioenvironmental Sciences, Kyushu University , Fukuoka , Japan.
FAU - Tran, P V
AU  - Tran PV
AD  - a Laboratory of Regulation in Metabolism and Behavior , Graduate School of 
      Bioresource and Bioenvironmental Sciences, Kyushu University , Fukuoka , Japan.
FAU - Bahry, M A
AU  - Bahry MA
AD  - a Laboratory of Regulation in Metabolism and Behavior , Graduate School of 
      Bioresource and Bioenvironmental Sciences, Kyushu University , Fukuoka , Japan.
FAU - Yang, H
AU  - Yang H
AD  - a Laboratory of Regulation in Metabolism and Behavior , Graduate School of 
      Bioresource and Bioenvironmental Sciences, Kyushu University , Fukuoka , Japan.
FAU - Han, G
AU  - Han G
AD  - a Laboratory of Regulation in Metabolism and Behavior , Graduate School of 
      Bioresource and Bioenvironmental Sciences, Kyushu University , Fukuoka , Japan.
FAU - Tsuchiya, A
AU  - Tsuchiya A
AD  - b R&D Division , Meiji Co., Ltd. , Kanagawa , Japan.
FAU - Asami, Y
AU  - Asami Y
AD  - b R&D Division , Meiji Co., Ltd. , Kanagawa , Japan.
FAU - Furuse, M
AU  - Furuse M
AD  - a Laboratory of Regulation in Metabolism and Behavior , Graduate School of 
      Bioresource and Bioenvironmental Sciences, Kyushu University , Fukuoka , Japan.
FAU - Chowdhury, V S
AU  - Chowdhury VS
AUID- ORCID: 0000-0001-6709-2788
AD  - c Division for Experimental Natural Science, Faculty of Arts and Science , 
      Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University , 
      Fukuoka , Japan.
LA  - eng
PT  - Journal Article
DEP - 20170612
PL  - England
TA  - Br Poult Sci
JT  - British poultry science
JID - 15740290R
RN  - 0 (Avian Proteins)
RN  - 0 (Mitochondrial Proteins)
RN  - 4SR0Q8YD1X (D-Aspartic Acid)
SB  - IM
MH  - Administration, Oral
MH  - Animal Husbandry
MH  - Animals
MH  - Avian Proteins/*genetics
MH  - Bacteria/*chemistry
MH  - Body Temperature
MH  - Chickens/growth & development/*physiology
MH  - D-Aspartic Acid/*administration & dosage/*metabolism
MH  - Gene Expression
MH  - Hot Temperature
MH  - Male
MH  - Mitochondrial Proteins/*genetics
MH  - Random Allocation
OTO - NOTNLM
OT  - Bacteria
OT  - D-aspartate
OT  - chicks
OT  - mitochondrial genes
OT  - rectal temperature
EDAT- 2017/05/27 06:00
MHDA- 2018/05/15 06:00
CRDT- 2017/05/27 06:00
PHST- 2017/05/27 06:00 [pubmed]
PHST- 2018/05/15 06:00 [medline]
PHST- 2017/05/27 06:00 [entrez]
AID - 10.1080/00071668.2017.1335858 [doi]
PST - ppublish
SO  - Br Poult Sci. 2017 Oct;58(5):569-577. doi: 10.1080/00071668.2017.1335858. Epub 
      2017 Jun 12.