PMID- 28553874
OWN - NLM
STAT- MEDLINE
DCOM- 20171204
LR  - 20171204
IS  - 1897-4279 (Electronic)
IS  - 0022-9032 (Linking)
VI  - 75
IP  - 8
DP  - 2017
TI  - Clinical significance and determinants of prompt recruitment collaterals during 
      primary percutaneous coronary intervention.
PG  - 763-769
LID - 10.5603/KP.a2017.0078 [doi]
AB  - BACKGROUND: Due to ischaemic time delays from the chest pain occurrence in acute 
      ST elevation myocardial infarction (STEMI), prompt recruitment collaterals 
      (PRCCs) to infarct-related artery (IRA) are the major protective structures 
      during this period. AIM: We aimed to investigate the clinical significance and 
      determinants of PRCCs in acute STEMI patients. METHODS: A total of 1375 
      consecutive acute STEMI patients were prospectively enrolled in the study. The 
      patients were divided into two groups, according to PRCCs to IRA; Rentrop </= 1 
      were defined as inadequate collateral development (ICD) group and Rentrop >/= 2 
      defined as adequate collateral development (ACD) group. RESULTS: Patients in the 
      ICD group had higher incidence of baseline risk characteristics, including older 
      age, hypertension, and diabetes mellitus; however, pre-infarct angina incidence 
      was lower than in the ACD group (p < 0.05 for all). In addition, the ICD group 
      had worse haemodynamic status on admission and 30-day mortality. Compared to the 
      ACD group, the non-IRA chronic total occlusion (CTO), peak troponin-T, N-terminal 
      pro-B-type natriuretic peptide (NT-proBNP), and high sensitivity C-reactive 
      protein (hs-CRP) levels were higher in the ICD group. On multivariate logistic 
      regression analysis, non-IRA CTO (b = 3.114, 95% CI 1.382-7.017, p < 0.006) with 
      pre-infarction angina together with higher values of peak troponin-T, NT-proBNP, 
      and hs-CRP were associated with PRCCs in acute STEMI. CONCLUSIONS: Taking into 
      account that the main message of the study is that if patients have higher 
      cardiac biomarkers and adverse clinical findings (which, of note, may show the 
      extent of myocardial infarction) and have non-IRA CTO, there is a higher chance 
      that they will have inadequate collateralisation.
FAU - Sen, Omer
AU  - Sen O
AD  - Department of Cardiology, Adana Numune Training and Research Hospital, Adana, 
      Turkey, Turkey. kardiyosen@gmail.com.
FAU - Allahverdiyev, Samir
AU  - Allahverdiyev S
FAU - Topuz, Mustafa
AU  - Topuz M
FAU - Baykan, Ahmet Oytun
AU  - Baykan AO
FAU - Oz, Fahrettin
AU  - Oz F
FAU - Koc, Mevlut
AU  - Koc M
LA  - eng
PT  - Journal Article
DEP - 20170529
PL  - Poland
TA  - Kardiol Pol
JT  - Kardiologia polska
JID - 0376352
RN  - 0 (Peptide Fragments)
RN  - 0 (Troponin T)
RN  - 0 (pro-brain natriuretic peptide (1-76))
RN  - 114471-18-0 (Natriuretic Peptide, Brain)
RN  - 9007-41-4 (C-Reactive Protein)
SB  - IM
MH  - Aged
MH  - C-Reactive Protein/analysis
MH  - *Coronary Circulation
MH  - Female
MH  - Hemodynamics
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Natriuretic Peptide, Brain/blood
MH  - Peptide Fragments/blood
MH  - *Percutaneous Coronary Intervention
MH  - ST Elevation Myocardial Infarction/blood/*surgery
MH  - Treatment Outcome
MH  - Troponin T/blood
OTO - NOTNLM
OT  - ST elevation myocardial infarction
OT  - arteriogenesis
OT  - chronic total occlusion
OT  - collateral network
OT  - mortality
EDAT- 2017/05/30 06:00
MHDA- 2017/12/05 06:00
CRDT- 2017/05/30 06:00
PHST- 2016/07/09 00:00 [received]
PHST- 2017/01/12 00:00 [accepted]
PHST- 2016/12/29 00:00 [revised]
PHST- 2017/05/30 06:00 [pubmed]
PHST- 2017/12/05 06:00 [medline]
PHST- 2017/05/30 06:00 [entrez]
AID - VM/OJS/KP/10741 [pii]
AID - 10.5603/KP.a2017.0078 [doi]
PST - ppublish
SO  - Kardiol Pol. 2017;75(8):763-769. doi: 10.5603/KP.a2017.0078. Epub 2017 May 29.