PMID- 28571077
OWN - NLM
STAT- MEDLINE
DCOM- 20180917
LR  - 20181202
IS  - 1439-0795 (Electronic)
IS  - 0176-3679 (Linking)
VI  - 51
IP  - 3
DP  - 2018 May
TI  - A Systematic Review of Mechanisms of Change in Body-Oriented Yoga in Major 
      Depressive Disorders.
PG  - 73-81
LID - 10.1055/s-0043-111013 [doi]
AB  - INTRODUCTION: Despite empirical evidence for the efficacy of body-oriented yoga 
      as add-on treatment for major depressive disorder (MDD), the specific mechanisms 
      by which yoga leads to therapeutic changes remain unclear. By means of a 
      systematic review, we evaluate how the field is progressing in its empirical 
      investigation of mechanisms of change in yoga for MDD. METHODS: To identify 
      relevant studies, a systematic search was conducted. RESULTS: The search produced 
      441 articles, of which 5 were included, that empirically examined 2 psychological 
      mechanisms (mindfulness, rumination) and 3 biological mechanisms (vagal control, 
      heart rate variability [HRV], brain-derived neurotrophic factor [BDNF], 
      cortisol). 2 studies found that decreased rumination and 1 study that increased 
      mindfulness was associated with the effect of yoga on treatment outcome. In 
      addition, preliminary studies suggest that alterations in cortisol, BDNF, and HRV 
      may play a role in how yoga exerts its clinical effect. DISCUSSION: The results 
      suggest that body-oriented yoga could work through some of the theoretically 
      predicted mechanisms. However, there is a need for more rigorous designs that can 
      assess greater levels of causal specificity.
CI  - (c) Georg Thieme Verlag KG Stuttgart . New York.
FAU - Meister, Klara
AU  - Meister K
AD  - Department of Psychiatry, Psychotherapy and Preventive Medicine Ruhr University 
      Bochum, LWL University Hospital, Bochum, Germany.
FAU - Juckel, Georg
AU  - Juckel G
AD  - Department of Psychiatry, Psychotherapy and Preventive Medicine Ruhr University 
      Bochum, LWL University Hospital, Bochum, Germany.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20170601
PL  - Germany
TA  - Pharmacopsychiatry
JT  - Pharmacopsychiatry
JID - 8402938
RN  - 0 (Brain-Derived Neurotrophic Factor)
RN  - 7171WSG8A2 (BDNF protein, human)
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - Brain-Derived Neurotrophic Factor/metabolism
MH  - Databases, Factual
MH  - Depressive Disorder, Major/physiopathology/psychology/*rehabilitation
MH  - Heart Rate/physiology
MH  - Humans
MH  - Hydrocortisone/metabolism
MH  - *Treatment Outcome
MH  - *Yoga
COIS- The authors declare no conflict of interest.
EDAT- 2017/06/02 06:00
MHDA- 2018/09/18 06:00
CRDT- 2017/06/02 06:00
PHST- 2017/06/02 06:00 [pubmed]
PHST- 2018/09/18 06:00 [medline]
PHST- 2017/06/02 06:00 [entrez]
AID - 10.1055/s-0043-111013 [doi]
PST - ppublish
SO  - Pharmacopsychiatry. 2018 May;51(3):73-81. doi: 10.1055/s-0043-111013. Epub 2017 
      Jun 1.