PMID- 28577832 OWN - NLM STAT- MEDLINE DCOM- 20180410 LR - 20220330 IS - 1532-9461 (Electronic) IS - 1053-4296 (Linking) VI - 27 IP - 3 DP - 2017 Jul TI - Advances in Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma. PG - 247-255 LID - S1053-4296(17)30018-8 [pii] LID - 10.1016/j.semradonc.2017.02.002 [doi] AB - Stereotactic Body Radiation Therapy (SBRT) is an emerging effective treatment for hepatocellular carcinoma (HCC) associated with acceptable rates of toxicity in appropriately selected patients. Despite often being reserved for patients unsuitable for other local treatments, prospective and retrospective studies have demonstrated excellent long-term control. SBRT may be used as a stand-alone treatment, or as an adjunct to other HCC therapies. Based on available data, SBRT appears to complement existing local liver therapies. Randomized and nonrandomized comparative studies are required to better determine the optimal role of SBRT in HCC treatment. CI - Copyright (c) 2017 Elsevier Inc. All rights reserved. FAU - Murray, Louise J AU - Murray LJ AD - Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada; Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada. FAU - Dawson, Laura A AU - Dawson LA AD - Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada; Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada. Electronic address: laura.dawson@rmp.uhn.on.ca. LA - eng PT - Journal Article PT - Review DEP - 20170220 PL - United States TA - Semin Radiat Oncol JT - Seminars in radiation oncology JID - 9202882 SB - IM MH - Carcinoma, Hepatocellular/*radiotherapy MH - Humans MH - Liver Neoplasms/*radiotherapy MH - Prospective Studies MH - Radiosurgery/*methods MH - Retrospective Studies EDAT- 2017/06/05 06:00 MHDA- 2018/04/11 06:00 CRDT- 2017/06/05 06:00 PHST- 2017/06/05 06:00 [entrez] PHST- 2017/06/05 06:00 [pubmed] PHST- 2018/04/11 06:00 [medline] AID - S1053-4296(17)30018-8 [pii] AID - 10.1016/j.semradonc.2017.02.002 [doi] PST - ppublish SO - Semin Radiat Oncol. 2017 Jul;27(3):247-255. doi: 10.1016/j.semradonc.2017.02.002. Epub 2017 Feb 20.