PMID- 28583268 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20191120 IS - 2173-9188 (Electronic) IS - 1130-1406 (Linking) VI - 34 IP - 3 DP - 2017 Jul-Sep TI - Voice disorders in residual paracoccidioidomycosis in upper airways and digestive tract. PG - 180-184 LID - S1130-1406(17)30048-7 [pii] LID - 10.1016/j.riam.2017.01.003 [doi] AB - BACKGROUND: Paracoccidioidomycosis (PCM) is a systemic mycosis of acute and chronic evolution, caused by species belonging to the genus Paracoccidioides. It is considered the most prevalent systemic endemic mycosis in Latin America, with cases in the tropical and subtropical regions. Residual PCM refers to the fibrotic scar sequelae resulting from the disease treatment which, when associated with collagen accumulation, leads to functional and anatomic alterations in the organs. AIMS: The aim of this study was to evaluate the vocal function of patients with residual PCM in upper airways and digestive tract. METHODS: We performed a cross-sectional study in 2010 in a cohort of 21 patients with residual PCM in upper airways and digestive tract. RESULTS: The average age was 49.48+/-9.1 years, and only two (9.5%) patients were female. The study was performed in the 1-113 month-period (median 27) after the end of drug treatment. Five (23.8%) patients had alterations in the larynx as a sequela of the disease. However, all patients had vocal changes in vocal auditory perceptual analysis by GRBASI scale. The computerized acoustic analysis using the software Vox Metria, showed that 11 patients (52.4%) presented alterations in jitter, 15 (71.4%) in shimmer, 8 (38.1%) in F0, 4 (19%) in glottal to noise excitation (GNE), 7 (33.3%) in the presence of noise and 12 (57.1%) in the presence of vibratory irregularity. CONCLUSIONS: The great frequency of alterations in residual PCM suggests that the patients in such phase could benefit from a multidisciplinary treatment, offering them integral monitoring of the disease, including speech rehabilitation after the PCM is healed. CI - Copyright (c) 2017 Asociacion Espanola de Micologia. Publicado por Elsevier Espana, S.L.U. All rights reserved. FAU - da Costa, Ananda Dutra AU - da Costa AD AD - National Institute of Infectious Diseases, Oswaldo Cruz Foundation, INI/FIOCRUZ, Rio de Janeiro, RJ, Brazil. FAU - Vargas, Amanda Pereira AU - Vargas AP AD - Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil. FAU - Lucena, Marcia Mendonca AU - Lucena MM AD - National Institute of Infectious Diseases, Oswaldo Cruz Foundation, INI/FIOCRUZ, Rio de Janeiro, RJ, Brazil; Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil. FAU - Ruas, Ana Cristina Nunes AU - Ruas ACN AD - Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil. FAU - Braga, Fernanda da Silva Santos AU - Braga FDSS AD - National Institute of Infectious Diseases, Oswaldo Cruz Foundation, INI/FIOCRUZ, Rio de Janeiro, RJ, Brazil. FAU - Bom-Braga, Mateus Pereira AU - Bom-Braga MP AD - National Institute of Infectious Diseases, Oswaldo Cruz Foundation, INI/FIOCRUZ, Rio de Janeiro, RJ, Brazil. FAU - Bom-Braga, Frederico Pereira AU - Bom-Braga FP AD - National Institute of Infectious Diseases, Oswaldo Cruz Foundation, INI/FIOCRUZ, Rio de Janeiro, RJ, Brazil. FAU - do Valle, Antonio Carlos Francesconi AU - do Valle ACF AD - National Institute of Infectious Diseases, Oswaldo Cruz Foundation, INI/FIOCRUZ, Rio de Janeiro, RJ, Brazil. FAU - Igreja, Ricardo Pereira AU - Igreja RP AD - Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil. FAU - Valete-Rosalino, Claudia Maria AU - Valete-Rosalino CM AD - National Institute of Infectious Diseases, Oswaldo Cruz Foundation, INI/FIOCRUZ, Rio de Janeiro, RJ, Brazil; Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil. Electronic address: claudia.valete@ini.fiocruz.br. LA - eng PT - Journal Article DEP - 20170603 PL - Spain TA - Rev Iberoam Micol JT - Revista iberoamericana de micologia JID - 9425531 OTO - NOTNLM OT - Calidad vocal OT - Disfonia OT - Dysphonia OT - Laringe OT - Larynx OT - Logopedia OT - Paracoccidioidomicosis OT - Paracoccidioidomycosis OT - Speech therapy OT - Vocal quality EDAT- 2017/06/07 06:00 MHDA- 2017/06/07 06:01 CRDT- 2017/06/07 06:00 PHST- 2016/05/18 00:00 [received] PHST- 2016/11/18 00:00 [revised] PHST- 2017/01/04 00:00 [accepted] PHST- 2017/06/07 06:00 [pubmed] PHST- 2017/06/07 06:01 [medline] PHST- 2017/06/07 06:00 [entrez] AID - S1130-1406(17)30048-7 [pii] AID - 10.1016/j.riam.2017.01.003 [doi] PST - ppublish SO - Rev Iberoam Micol. 2017 Jul-Sep;34(3):180-184. doi: 10.1016/j.riam.2017.01.003. Epub 2017 Jun 3.