PMID- 28593351
OWN - NLM
STAT- MEDLINE
DCOM- 20190207
LR  - 20190215
IS  - 1433-0563 (Electronic)
IS  - 0340-2592 (Linking)
VI  - 56
IP  - 10
DP  - 2017 Oct
TI  - [What is the perception of the 10-point plan of the German Federal Ministry of 
      Health against multidrug-resistant pathogens and measures of antibiotic 
      stewardship? : An interdisciplinary analysis among German clinicians and 
      development of a decision tool for urologists].
PG  - 1302-1310
LID - 10.1007/s00120-017-0425-1 [doi]
AB  - BACKGROUND: Due to increasing antibiotic resistances, relevant treatment problems 
      are currently emerging in clinical practice. In March 2015, the German Federal 
      Ministry of Health (BMG) published a 10-point plan designed to combat this 
      development. Furthermore, the first German guideline on antibiotic stewardship 
      (ABS) was implemented in 2013 and instructs physicians of different specialties 
      about several treatment considerations. Evidence is scarce on how such concepts 
      (10-point plan/BMG, ABS) are perceived among clinicians. MATERIALS AND METHODS: 
      Within the MR2 study (Multiinstitutional Reconnaissance of practice with 
      MultiResistant bacteria - a survey focusing on German hospitals), a questionnaire 
      including 4 + 35 items was sent to 18 German hospitals between August and October 
      2015, surveying internists, gynecologists, general surgeons, and urologists. 
      Using multivariate logistic regression models (MLRM), the impact of medical 
      specialty and further criteria on the endpoints (1) awareness of the 10-point 
      plan/BMG and (2) knowledge of ABS measures were assessed. Fulfillment of 
      endpoints was predefined when average or full knowledge was reported (reference: 
      poor to no knowledge). RESULTS: Overall response rate was 43% (456/1061) for 
      fully evaluable questionnaires. Only 63.0 and 53.6% of urologists and 
      nonurologists (internists, gynecologists, and general surgeons), respectively, 
      attended training courses regarding multidrug-resistance or antibiotic 
      prescribing in the 12 months prior to the study (P = 0.045). The endpoints 
      average and full knowledge regarding 10-point plan/BMG and ABS measures were 
      fulfilled in only 31.4 and 32.8%, respectively. In MLRM, clinicians with at least 
      one previous training course (reference: no training course) were 2.5- and 
      3.8-fold more likely to meet respective endpoint criteria (all P < 0.001). 
      Medical specialty (urologists vs. nonurologists) did not significantly impact the 
      endpoints in both MLRM. CONCLUSIONS: The 10-point plan/BMG and ABS programs 
      should be implemented into clinical practice, but awareness and knowledge of both 
      is insufficient. Thus, it stands to reason that the actual realization of such 
      measures is inadequate and continuous training towards rational prescription of 
      antibiotics is necessary, regardless of medical specialty.
FAU - May, M
AU  - May M
AD  - Urologische Klinik, St. Elisabeth Klinikum, St.-Elisabeth-Str. 23, 94315, 
      Straubing, Deutschland. matthias.may@klinikum-straubing.de.
FAU - Vetterlein, M W
AU  - Vetterlein MW
AD  - Urologische Universitatsklinik, Universitatsklinikum Hamburg-Eppendorf, 
      Martinistr. 52, 20246, Hamburg, Deutschland.
FAU - Wagenlehner, F M
AU  - Wagenlehner FM
AD  - Urologische Universitatsklinik, Justus-Liebig Universitatsklinikum, 
      Rudolf-Buchheim-Str. 7, 35392, Giessen, Deutschland.
FAU - Brookman-May, S D
AU  - Brookman-May SD
AD  - Klinik fur Urologie, LMU Munchen, Marchioninistrasse 15, 81377, Munchen, 
      Deutschland.
FAU - Gilfrich, C
AU  - Gilfrich C
AD  - Urologische Klinik, St. Elisabeth Klinikum, St.-Elisabeth-Str. 23, 94315, 
      Straubing, Deutschland.
FAU - Fritsche, H-M
AU  - Fritsche HM
AD  - Urologische Universitatsklinik, Universitat Regensburg, Landshuter Strasse 65, 
      93053, Regensburg, Deutschland.
FAU - Spachmann, P J
AU  - Spachmann PJ
AD  - Urologische Universitatsklinik, Universitat Regensburg, Landshuter Strasse 65, 
      93053, Regensburg, Deutschland.
FAU - Burger, M
AU  - Burger M
AD  - Urologische Universitatsklinik, Universitat Regensburg, Landshuter Strasse 65, 
      93053, Regensburg, Deutschland.
FAU - Schostak, M
AU  - Schostak M
AD  - Urologische Universitatsklinik, Universitatsklinikum Otto-von-Guericke University 
      Magdeburg, Leipziger Str. 44, 39120, Magdeburg, Deutschland.
FAU - Lebentrau, S
AU  - Lebentrau S
AD  - Urologische Klinik, Ruppiner Kliniken, Fehrbelliner Str. 38, 16816, Neuruppin, 
      Deutschland.
CN  - MR2-Studiengruppe
LA  - ger
PT  - Journal Article
TT  - Wie werden der 10-Punkte-Plan des Deutschen Bundesministeriums fur Gesundheit zur 
      Bekampfung resistenter Erreger und Massnahmen des Antibiotic Stewardship 
      wahrgenommen? : Eine fachubergreifende Analyse der Kenntnis deutscher Klinikarzte 
      und Entwicklung einer urologischen Handlungsanweisung.
PL  - Germany
TA  - Urologe A
JT  - Der Urologe. Ausg. A
JID - 1304110
SB  - IM
MH  - Antimicrobial Stewardship/*legislation & jurisprudence
MH  - Attitude of Health Personnel
MH  - *Drug Resistance, Multiple, Bacterial
MH  - Germany
MH  - Humans
MH  - *Interdisciplinary Communication
MH  - *Intersectoral Collaboration
MH  - National Health Programs/*legislation & jurisprudence
MH  - Surveys and Questionnaires
MH  - Urology/*legislation & jurisprudence
OTO - NOTNLM
OT  - Antibiotic stewardship
OT  - Further education
OT  - Medical specialties
OT  - Multidrug resistance
OT  - Surveys and questionnaires
EDAT- 2017/06/09 06:00
MHDA- 2019/02/08 06:00
CRDT- 2017/06/09 06:00
PHST- 2017/06/09 06:00 [pubmed]
PHST- 2019/02/08 06:00 [medline]
PHST- 2017/06/09 06:00 [entrez]
AID - 10.1007/s00120-017-0425-1 [pii]
AID - 10.1007/s00120-017-0425-1 [doi]
PST - ppublish
SO  - Urologe A. 2017 Oct;56(10):1302-1310. doi: 10.1007/s00120-017-0425-1.