PMID- 28593369
OWN - NLM
STAT- MEDLINE
DCOM- 20180409
LR  - 20191210
IS  - 1618-2650 (Electronic)
IS  - 1618-2642 (Linking)
VI  - 409
IP  - 20
DP  - 2017 Aug
TI  - Miniaturised sample preparation method for the multiresidual determination of 
      regulated organohalogenated pollutants and related compounds in wild bird eggs.
PG  - 4905-4913
LID - 10.1007/s00216-017-0432-5 [doi]
AB  - A simplified, miniaturised matrix solid-phase dispersion (MSPD)-based method 
      allowing the simultaneous extraction and purification of contaminants belonging 
      to selected families of regulated persistent organic pollutants (POPs), i.e. 
      polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs) and penta- to 
      octa-polybrominated diphenyl ethers (PBDEs), and related contaminants of emerging 
      concern, such as deca-BDE and Dechlorane Plus (DP), has been proposed. Wild bird 
      eggs were used as biotic fat-containing model matrices. Once optimised, the 
      procedure allowed sample preparation to be accomplished within 30 min, in a 
      single step, and with minimal sample and reagent consumption and waste 
      generation. These features contributed to speeding up and greening the analytical 
      process as compared to the large-scale multistep procedures for these types of 
      analyses. The method was combined with gas chromatography-quadrupole mass 
      spectrometry (GC-qMS) for PCB and OCP analysis and with GC-negative ion chemical 
      ionisation-quadrupole mass spectrometry (NCI-qMS) for PBDE and DP determination. 
      The complete analytical method provided satisfactory recoveries of the target 
      compounds (above 83% for all analytes, except for PBDE 209, 63%), although as 
      small an amount of sample as 0.300 g was used. The repeatability of the complete 
      procedure was less than 16% (with the only exception for PCB 153, which looked to 
      be affected by an interference). The limits of detection were in all cases lower 
      than 34 pg g(-1) dry weight (as calculated for real samples), demonstrating the 
      feasibility of the proposed procedure for accurate determination of the target 
      compounds in biological samples. The proposed procedure was applied to the 
      analysis of the target POPs in unhatched eggs of wild bird species. Graphical 
      abstract Scheme of the miniaturised methodology proposed for environmental 
      monitoring of POPs and related compounds in wild bird eggs.
FAU - Roscales, Jose L
AU  - Roscales JL
AD  - Department of Instrumental Analysis and Environmental Chemistry, Institute of 
      Organic Chemistry, CSIC (IQOG-CSIC), Juan de la Cierva 3, 28006, Madrid, Spain.
FAU - Vicente, Alba
AU  - Vicente A
AD  - Department of Instrumental Analysis and Environmental Chemistry, Institute of 
      Organic Chemistry, CSIC (IQOG-CSIC), Juan de la Cierva 3, 28006, Madrid, Spain.
FAU - Ramos, Lourdes
AU  - Ramos L
AD  - Department of Instrumental Analysis and Environmental Chemistry, Institute of 
      Organic Chemistry, CSIC (IQOG-CSIC), Juan de la Cierva 3, 28006, Madrid, Spain. 
      l.ramos@iqog.csic.es.
FAU - Jimenez, Begona
AU  - Jimenez B
AD  - Department of Instrumental Analysis and Environmental Chemistry, Institute of 
      Organic Chemistry, CSIC (IQOG-CSIC), Juan de la Cierva 3, 28006, Madrid, Spain.
LA  - eng
PT  - Journal Article
PT  - Validation Study
DEP - 20170607
PL  - Germany
TA  - Anal Bioanal Chem
JT  - Analytical and bioanalytical chemistry
JID - 101134327
RN  - 0 (Environmental Pollutants)
RN  - 0 (Halogens)
SB  - IM
MH  - Animals
MH  - Birds
MH  - Eggs/*analysis
MH  - Environmental Pollutants/*analysis
MH  - Halogens/*analysis
MH  - Limit of Detection
MH  - *Miniaturization
MH  - Quality Control
MH  - Reproducibility of Results
OTO - NOTNLM
OT  - DPs
OT  - MSPD
OT  - Miniaturisation
OT  - Multiresidual analysis
OT  - PBDEs
OT  - POPs
EDAT- 2017/06/09 06:00
MHDA- 2018/04/10 06:00
CRDT- 2017/06/09 06:00
PHST- 2017/03/30 00:00 [received]
PHST- 2017/05/24 00:00 [accepted]
PHST- 2017/05/18 00:00 [revised]
PHST- 2017/06/09 06:00 [pubmed]
PHST- 2018/04/10 06:00 [medline]
PHST- 2017/06/09 06:00 [entrez]
AID - 10.1007/s00216-017-0432-5 [pii]
AID - 10.1007/s00216-017-0432-5 [doi]
PST - ppublish
SO  - Anal Bioanal Chem. 2017 Aug;409(20):4905-4913. doi: 10.1007/s00216-017-0432-5. 
      Epub 2017 Jun 7.