PMID- 28596918
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2090-004X (Print)
IS  - 2090-0058 (Electronic)
IS  - 2090-004X (Linking)
VI  - 2017
DP  - 2017
TI  - Physical Activity and Quality of Life in Retinitis Pigmentosa.
PG  - 6950642
LID - 10.1155/2017/6950642 [doi]
LID - 6950642
AB  - PURPOSE: Aerobic exercise has been found to be neuroprotective in animal models 
      of retinal degeneration. This study aims to report physical activity levels in 
      patients with RP and investigate the relationship between physical activity and 
      vision-related quality-of-life (QOL). MATERIALS AND METHODS: A retrospective 
      study of adult patients with RP examined in 2005-2014. Physical activity levels 
      were assessed using the Godin Exercise Questionnaire. The NEI-Visual Function 
      Questionaire-25 (VFQ-25), SF-36 General Health survey, and Pepper Assessment Tool 
      for Disability (PAT-D) were administered. RESULTS: 143 patients participated. 81 
      (56.6%) patients were classified as "active" and 62 (43.4%) as "insufficiently 
      active" by Godin score. VFQ-25 revealed statistically significant differences 
      between the active and insufficiently active patients, including overall visual 
      function (53.3 versus 45.1, p = 0.010), color vision (73.8 versus 52.9, p < 
      0.001), and peripheral vision (34.3 versus 23.8, p = 0.021). The physical 
      component of the SF-36 and the PAT-D survey also demonstrated statistically 
      significant differences (47.2 versus 52.9, p = 0.002; 24.3 versus 30.0, p = 
      0.010). Active patients had a higher initial Goldmann visual field (GVF) score 
      (74.8 versus 60.1 degrees, p = 0.255) and final GVF score (78.7 versus 47.1 
      degrees, p = 0.069) but did not reach statistical significance. CONCLUSIONS: In 
      RP, increased physical activity is associated with greater self-reported visual 
      function and QOL.
FAU - Levinson, Joshua D
AU  - Levinson JD
AUID- ORCID: 0000-0002-9612-6411
AD  - Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, 
      USA.
FAU - Joseph, Ethan
AU  - Joseph E
AD  - Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, 
      USA.
FAU - Ward, Laura A
AU  - Ward LA
AD  - Rollins School of Public Health, Emory University, Atlanta, GA, USA.
FAU - Nocera, Joe R
AU  - Nocera JR
AUID- ORCID: 0000-0002-3338-9927
AD  - Center for Visual and Neurocognitive Rehabilitation, Atlanta VA Medical Center, 
      Decatur, GA, USA.
AD  - Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
FAU - Pardue, Machelle T
AU  - Pardue MT
AD  - Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, 
      USA.
AD  - Center for Visual and Neurocognitive Rehabilitation, Atlanta VA Medical Center, 
      Decatur, GA, USA.
AD  - Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, 
      GA, USA.
FAU - Bruce, Beau B
AU  - Bruce BB
AD  - Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, 
      USA.
AD  - Rollins School of Public Health, Emory University, Atlanta, GA, USA.
FAU - Yan, Jiong
AU  - Yan J
AUID- ORCID: 0000-0003-1206-1540
AD  - Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, 
      USA.
LA  - eng
GR  - P30 EY006360/EY/NEI NIH HHS/United States
PT  - Journal Article
DEP - 20170517
PL  - United States
TA  - J Ophthalmol
JT  - Journal of ophthalmology
JID - 101524199
PMC - PMC5449727
EDAT- 2017/06/10 06:00
MHDA- 2017/06/10 06:01
PMCR- 2017/05/17
CRDT- 2017/06/10 06:00
PHST- 2017/01/04 00:00 [received]
PHST- 2017/03/12 00:00 [revised]
PHST- 2017/03/28 00:00 [accepted]
PHST- 2017/06/10 06:00 [entrez]
PHST- 2017/06/10 06:00 [pubmed]
PHST- 2017/06/10 06:01 [medline]
PHST- 2017/05/17 00:00 [pmc-release]
AID - 10.1155/2017/6950642 [doi]
PST - ppublish
SO  - J Ophthalmol. 2017;2017:6950642. doi: 10.1155/2017/6950642. Epub 2017 May 17.