PMID- 28601911
OWN - NLM
STAT- MEDLINE
DCOM- 20180427
LR  - 20181113
IS  - 1435-702X (Electronic)
IS  - 0721-832X (Linking)
VI  - 255
IP  - 9
DP  - 2017 Sep
TI  - Repeatability of ganglion cell-inner plexiform layer thickness measurements using 
      spectral-domain OCT in branch retinal vein occlusion.
PG  - 1727-1735
LID - 10.1007/s00417-017-3710-1 [doi]
AB  - PURPOSE: To analyze the repeatability of thickness measurements of the central 
      macula, ganglion cell-inner plexiform layer (GC-IPL), and retinal nerve fiber 
      layer (RNFL) using spectral-domain optical coherence tomography (SD-OCT) before 
      and after treatment of macular edema in branch retinal vein occlusion (BRVO). 
      METHODS: We analyzed patients with BRVO who visited our retinal clinic. The 
      repeatability of the thickness measurements were compared using the intraclass 
      correlation coefficient (ICC) and coefficient of variation (COV) of affected 
      versus normal fellow eyes. RESULTS: The average thicknesses of the central 
      macula, RNFL, and GC-IPL were 371.28 mum, 105.60 mum, and 61.88 mum, respectively, 
      in affected eyes with macular edema before treatment, and the ICCs were 0.978, 
      0.919, and 0.705, respectively. The average thicknesses were 244.98 mum, 96.70 mum, 
      and 82.70 mum, respectively, in affected eyes without macular edema after 
      treatment, and the ICCs were 0.999, 0.975, and 0.928, respectively. After 
      resolution of macular edema, the average thickness of the GC-IPL increased, 
      whereas that of the central macula and RNFL significantly decreased (P < 0.05); 
      all of the ICCs increased compared to pretreatment values. In normal fellow eyes, 
      the average thicknesses were 250.98 mum, 93.50 mum, and 83.84 mum, respectively, and 
      the ICCs were 0.996, 0.995, and 0.994, respectively. CONCLUSIONS: After treatment 
      of macular edema, the repeatability and thickness of the GC-IPL increased, along 
      with reduction in the central macular thickness. This resulted from 
      auto-segmentation errors following macular contour changes and unstable gazes of 
      the patients due to decreased visual acuities in BRVO with macular edema.
FAU - Lee, Yeon Hee
AU  - Lee YH
AD  - Department of Ophthalmology, Chungnam National University College of Medicine, 
      Daejeon, Republic of Korea.
FAU - Kim, Min-Su
AU  - Kim MS
AD  - Department of Ophthalmology, Chungnam National University College of Medicine, 
      Daejeon, Republic of Korea.
FAU - Ahn, Seung Il
AU  - Ahn SI
AD  - Maleunnoon eye clinic, Daejeon, Republic of Korea.
FAU - Park, Hye Jin
AU  - Park HJ
AD  - Department of Ophthalmology, Chungnam National University College of Medicine, 
      Daejeon, Republic of Korea.
FAU - Shin, Kyung Sup
AU  - Shin KS
AD  - Department of Ophthalmology, Chungnam National University College of Medicine, 
      Daejeon, Republic of Korea.
FAU - Kim, Jung-Yeul
AU  - Kim JY
AD  - Department of Ophthalmology, Chungnam National University College of Medicine, 
      Daejeon, Republic of Korea. kimjy@cnu.ac.kr.
AD  - Department of Ophthalmology, Chungnam National University Hospital, #640 
      Daesa-dong, Jung-gu, Daejeon, 301-721, South Korea. kimjy@cnu.ac.kr.
LA  - eng
PT  - Journal Article
DEP - 20170611
PL  - Germany
TA  - Graefes Arch Clin Exp Ophthalmol
JT  - Graefe's archive for clinical and experimental ophthalmology = Albrecht von 
      Graefes Archiv fur klinische und experimentelle Ophthalmologie
JID - 8205248
SB  - IM
MH  - Adult
MH  - Aged
MH  - Disease Progression
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Macula Lutea/pathology
MH  - Male
MH  - Middle Aged
MH  - Nerve Fibers/*pathology
MH  - Prospective Studies
MH  - Retinal Ganglion Cells/*pathology
MH  - Retinal Vein Occlusion/*diagnosis
MH  - Tomography, Optical Coherence/*statistics & numerical data
OTO - NOTNLM
OT  - Branch retinal vein occlusion
OT  - Macular edema
OT  - Optical coherence tomography
OT  - Repeatability
EDAT- 2017/06/12 06:00
MHDA- 2018/04/28 06:00
CRDT- 2017/06/12 06:00
PHST- 2017/02/02 00:00 [received]
PHST- 2017/05/30 00:00 [accepted]
PHST- 2017/04/28 00:00 [revised]
PHST- 2017/06/12 06:00 [pubmed]
PHST- 2018/04/28 06:00 [medline]
PHST- 2017/06/12 06:00 [entrez]
AID - 10.1007/s00417-017-3710-1 [pii]
AID - 10.1007/s00417-017-3710-1 [doi]
PST - ppublish
SO  - Graefes Arch Clin Exp Ophthalmol. 2017 Sep;255(9):1727-1735. doi: 
      10.1007/s00417-017-3710-1. Epub 2017 Jun 11.