PMID- 28604339
OWN - NLM
STAT- MEDLINE
DCOM- 20181211
LR  - 20181211
IS  - 2530-0172 (Electronic)
IS  - 2530-0164 (Linking)
VI  - 64
IP  - 6
DP  - 2017 Jun-Jul
TI  - Obesity markers associated to albuminuria in a primary care center in Lima, Peru.
PG  - 295-302
LID - S2530-0164(17)30123-4 [pii]
LID - 10.1016/j.endinu.2017.03.012 [doi]
AB  - OBJECTIVE: To evaluate the association between three obesity markers, body mass 
      index (BMI), abdominal circumference (AC), waist to height ratio (WHtR), and 
      albuminuria in adults seen in a primary health care center specialized in chronic 
      diseases in Lima, Peru. METHODS: A cross-sectional, descriptive, retrospective 
      study in adults who attended a primary health care center specialized in chronic 
      diseases in 2011. Patients were divided into four categories: healthy subjects 
      and patients with high blood pressure, with type 2 diabetes mellitus (T2DM), and 
      with both diseases (HBP+T2DM). The main outcome was presence of albuminuria, 
      defined as urine albumin levels higher than 30mg/day. Exposure variables included 
      the following obesity markers: body mass index (BMI), waist-to-height ratio 
      (WHtR), and abdominal circumference (AC). Other covariates considered included 
      sex and age. Crude and adjusted Poisson regressions were performed to estimate 
      prevalence ratios (PRs) and their respective 95% confidence intervals (95% CIs). 
      Areas under the curve were calculated for each indicator, stratified by sex. 
      RESULTS: Data from 1,214 patients, 41% of them male, were analyzed, and 
      albuminuria was found in 14.2%. Albuminuria was found to be associated to AC and 
      WHtR, but not to BMI. All three parameters assessed had similar areas under the 
      curve. The optimum cut-off points found for BMI and AC in females were higher 
      than conventional (32.7kg/m(2) and 93cm respectively), while the values in males 
      were lower than conventional (27.9kg/m(2) and 100cm respectively). For WHtR, 
      however, the optimum cut-off point was higher in both sexes. The higher index in 
      females was for BMI, followed by AC and WHtR. In males, the higher index was for 
      WHtR, followed by AC and BMI. CONCLUSIONS: AC and WHtR were found to be directly 
      associated to albuminuria, while BMI was not associated to albuminuria. Areas 
      under the curve were similar for all three markers. The optimum cut-off points 
      for BMI and AC were higher than the conventional ones in females and lower in 
      males.
CI  - Copyright (c) 2017 SEEN. Publicado por Elsevier Espana, S.L.U. All rights reserved.
FAU - Quintanilla, Alberto E
AU  - Quintanilla AE
AD  - Centro de Atencion Integral de Diabetes e Hipertension (CEDHI)-EsSalud, Lima, 
      Peru; Facultad de Salud Publica y Administracion, Universidad Peruana Cayetano 
      Heredia, Lima, Peru. Electronic address: a_quintanillav@hotmail.com.
FAU - Taype-Rondan, Alvaro
AU  - Taype-Rondan A
AD  - CRONICAS Centro de Excelencia de Enfermedades Cronicas, Universidad Peruana 
      Cayetano Heredia, Lima, Peru.
FAU - Lazo-Porras, Maria
AU  - Lazo-Porras M
AD  - CRONICAS Centro de Excelencia de Enfermedades Cronicas, Universidad Peruana 
      Cayetano Heredia, Lima, Peru; Unidad de Conocimiento y Evidencia (CONEVID - 
      Universidad Peruana Cayetano Heredia), Lima, Peru.
FAU - Herrera-Anazco, Percy
AU  - Herrera-Anazco P
AD  - Hospital Nacional Dos de Mayo, Lima, Peru; Escuela de Medicina, Universidad 
      Peruana de Ciencias Aplicadas, Lima, Peru.
LA  - eng
LA  - spa
PT  - Journal Article
TT  - Marcadores de obesidad asociados a albuminuria en un centro de atencion primaria 
      de Lima, Peru.
DEP - 20170523
PL  - Spain
TA  - Endocrinol Diabetes Nutr
JT  - Endocrinologia, diabetes y nutricion
JID - 101698946
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Albuminuria/*epidemiology
MH  - Anemia/epidemiology
MH  - Area Under Curve
MH  - *Body Mass Index
MH  - Comorbidity
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/epidemiology
MH  - Female
MH  - Humans
MH  - Hypertension/epidemiology
MH  - Male
MH  - Middle Aged
MH  - Obesity/diagnosis/*epidemiology
MH  - Peru/epidemiology
MH  - Prevalence
MH  - Primary Health Care
MH  - ROC Curve
MH  - Regression Analysis
MH  - Retrospective Studies
MH  - *Waist Circumference
MH  - *Waist-Height Ratio
OTO - NOTNLM
OT  - Albuminuria
OT  - Diabetes tipo 2
OT  - High blood pressure
OT  - Hipertension arterial
OT  - Type 2 diabetes mellitus
OT  - Waist-to-height ratio.
OT  - Indice cintura/talla
EDAT- 2017/06/13 06:00
MHDA- 2018/12/12 06:00
CRDT- 2017/06/13 06:00
PHST- 2016/11/19 00:00 [received]
PHST- 2017/03/06 00:00 [revised]
PHST- 2017/03/29 00:00 [accepted]
PHST- 2017/06/13 06:00 [entrez]
PHST- 2017/06/13 06:00 [pubmed]
PHST- 2018/12/12 06:00 [medline]
AID - S2530-0164(17)30123-4 [pii]
AID - 10.1016/j.endinu.2017.03.012 [doi]
PST - ppublish
SO  - Endocrinol Diabetes Nutr. 2017 Jun-Jul;64(6):295-302. doi: 
      10.1016/j.endinu.2017.03.012. Epub 2017 May 23.