PMID- 28607553
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 1687-6369 (Print)
IS  - 1687-6377 (Electronic)
IS  - 1687-6369 (Linking)
VI  - 2017
DP  - 2017
TI  - Study of Testicular Structure in Fetuses with Prune Belly Syndrome.
PG  - 3254980
LID - 10.1155/2017/3254980 [doi]
LID - 3254980
AB  - PURPOSE: To compare the structure of the testis in fetuses with prune belly 
      syndrome (PBS) to normal controls. MATERIALS AND METHODS: We studied 6 testes 
      obtained from 3 fetuses with PBS and 14 testes from 7 male fetuses. The 
      testicular specimens were cut into 5-mum thick sections and stained with 
      hematoxylin and eosin (HE), to observe the seminiferous tubules; Weigert's 
      solution to observe elastic fibers; and picrosirius red to observe collagen. The 
      images were captured with an Olympus BX51 microscope and Olympus DP70 camera. The 
      stereological analysis was done with the Image Pro and Image J programs. Means 
      were statistically compared using the Mann-Whitney U test (p < 0.005). RESULTS: 
      Quantitative analysis documented no differences (p = 0.4) in number of 
      seminiferous tubules (ST) in PBS testes (mean = 8.87%, SD = 1.59), when compared 
      to the control (mean = 11.4%, SD = 2.99) and no differences (p = 0.8) in diameter 
      of ST in PBS testes (mean = 52.85 mum, SD = 1.58) when compared to the control 
      group (mean = 53.17 mum, SD = 1.55), but we did observe a lower number (p = 
      0.0002) of Leydig cells in the PBS testes (mean = 67.03% and SD = 3.697) when 
      compared to the control group (mean = 90.1% and SD = 2.986). CONCLUSIONS: Our 
      study showed a lower concentration of Leydig cells in the triad syndrome fetuses.
FAU - Favorito, Luciano A
AU  - Favorito LA
AUID- ORCID: 0000-0003-1562-6068
AD  - Urogenital Research Unit, State University of Rio de Janeiro, Rio de Janeiro, RJ, 
      Brazil.
FAU - Costa, Suelen F
AU  - Costa SF
AD  - Urogenital Research Unit, State University of Rio de Janeiro, Rio de Janeiro, RJ, 
      Brazil.
FAU - Costa, Waldemar S
AU  - Costa WS
AD  - Urogenital Research Unit, State University of Rio de Janeiro, Rio de Janeiro, RJ, 
      Brazil.
FAU - Vieiralves, Rodrigo
AU  - Vieiralves R
AD  - Urogenital Research Unit, State University of Rio de Janeiro, Rio de Janeiro, RJ, 
      Brazil.
FAU - Bernardo, Fabio O
AU  - Bernardo FO
AD  - Urogenital Research Unit, State University of Rio de Janeiro, Rio de Janeiro, RJ, 
      Brazil.
FAU - Sampaio, Francisco J B
AU  - Sampaio FJB
AD  - Urogenital Research Unit, State University of Rio de Janeiro, Rio de Janeiro, RJ, 
      Brazil.
LA  - eng
PT  - Journal Article
DEP - 20170521
PL  - Egypt
TA  - Adv Urol
JT  - Advances in urology
JID - 101476240
PMC - PMC5457755
EDAT- 2017/06/14 06:00
MHDA- 2017/06/14 06:01
PMCR- 2017/05/21
CRDT- 2017/06/14 06:00
PHST- 2016/10/15 00:00 [received]
PHST- 2017/05/03 00:00 [accepted]
PHST- 2017/06/14 06:00 [entrez]
PHST- 2017/06/14 06:00 [pubmed]
PHST- 2017/06/14 06:01 [medline]
PHST- 2017/05/21 00:00 [pmc-release]
AID - 10.1155/2017/3254980 [doi]
PST - ppublish
SO  - Adv Urol. 2017;2017:3254980. doi: 10.1155/2017/3254980. Epub 2017 May 21.