PMID- 28610682
OWN - NLM
STAT- MEDLINE
DCOM- 20171129
LR  - 20181202
IS  - 1873-4111 (Electronic)
IS  - 0378-5122 (Linking)
VI  - 102
DP  - 2017 Aug
TI  - Menopausal hormone therapy may increase non-allergic rhinitis among 
      postmenopausal women: Results from the Korea National Health and Nutrition 
      Examination Survey (2010-2012).
PG  - 46-49
LID - S0378-5122(17)30070-1 [pii]
LID - 10.1016/j.maturitas.2017.05.006 [doi]
AB  - OBJECTIVES: To investigate the association between menopausal hormone therapy 
      (MHT) and chronic rhinitis. METHODS: The data used in this study were derived 
      from the Korea National Health and Nutrition Examination Survey. The analysis 
      included 2967 postmenopausal women under 70 years of age, and there were no 
      missing data. Questionnaire responses regarding MHT, current life habits, 
      reproductive history, and rhinitis were reviewed. The levels of total 
      immunoglobulin E (IgE) and specific IgE for Dermatophagoides farinae, 
      cockroaches, and dogs were measured, using approximately 10% of all samples. We 
      compared women who were users of MHT and non-users of MHT. We also compared women 
      with and without chronic rhinitis. RESULTS: Of 2967 women matching the study 
      criteria, 567 were MHT users. The proportion of general rhinitis symptoms was 
      greater among MHT users (24.5%) than among MHT non-users (18.9%, p=0.003). The 
      proportion of cases of rhinorrhea or posterior nasal drip was also greater among 
      MHT users (6.3% vs. 4.3%, p=0.042), while there were no differences between the 
      two groups in the proportion of cases of nasal obstruction. There were no 
      differences in total IgE and specific IgE levels between the two groups. MHT was 
      used by 23.4% of women with chronic rhinitis and 18.0% of women without chronic 
      rhinitis. Age, waist circumference, and body mass index were also greater among 
      women without chronic rhinitis than among those with chronic rhinitis. 
      CONCLUSIONS: MHT may cause non-allergic rhinitis in postmenopausal women. Age and 
      obesity may also affect the occurrence of non-allergic rhinitis in postmenopausal 
      women.
CI  - Copyright (c) 2017 Elsevier B.V. All rights reserved.
FAU - Choi, Ji Ho
AU  - Choi JH
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang University 
      College of Medicine, Bucheon Hospital, Bucheon, Republic of Korea.
FAU - Hwang, Se Hwan
AU  - Hwang SH
AD  - Department of Otolaryngology-Head and Neck Surgery, Bucheon St. Mary's Hospital, 
      College of Medicine, The Catholic University of Korea, Bucheon, Republic of 
      Korea.
FAU - Suh, Jeffrey D
AU  - Suh JD
AD  - Department of Head and Neck Surgery, UCLA School of Medicine, Los Angeles, CA, 
      USA.
FAU - Kim, Jin Kook
AU  - Kim JK
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, 
      Konkuk University, Seoul, Republic of Korea.
FAU - Hong, Seok-Chan
AU  - Hong SC
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, 
      Konkuk University, Seoul, Republic of Korea.
FAU - Lim, Young Chang
AU  - Lim YC
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, 
      Konkuk University, Seoul, Republic of Korea.
FAU - Kim, Soo-Nyung
AU  - Kim SN
AD  - Department of Obstetrics and Gynecology, College of Medicine, Konkuk University, 
      Seoul, Republic of Korea.
FAU - Cho, Jae Hoon
AU  - Cho JH
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, 
      Konkuk University, Seoul, Republic of Korea. Electronic address: 
      jaehoon@kuh.ac.kr.
LA  - eng
PT  - Journal Article
DEP - 20170508
PL  - Ireland
TA  - Maturitas
JT  - Maturitas
JID - 7807333
SB  - IM
MH  - Adult
MH  - Aged
MH  - Female
MH  - *Hormone Replacement Therapy
MH  - Humans
MH  - Middle Aged
MH  - Nutrition Surveys
MH  - Obesity/epidemiology
MH  - *Postmenopause
MH  - Republic of Korea/epidemiology
MH  - Rhinitis/*epidemiology
MH  - Surveys and Questionnaires
OTO - NOTNLM
OT  - Menopausal hormone therapy
OT  - Non-allergic rhinitis
OT  - Postmenopausal
EDAT- 2017/06/15 06:00
MHDA- 2017/12/01 06:00
CRDT- 2017/06/15 06:00
PHST- 2017/02/08 00:00 [received]
PHST- 2017/03/26 00:00 [revised]
PHST- 2017/05/04 00:00 [accepted]
PHST- 2017/06/15 06:00 [entrez]
PHST- 2017/06/15 06:00 [pubmed]
PHST- 2017/12/01 06:00 [medline]
AID - S0378-5122(17)30070-1 [pii]
AID - 10.1016/j.maturitas.2017.05.006 [doi]
PST - ppublish
SO  - Maturitas. 2017 Aug;102:46-49. doi: 10.1016/j.maturitas.2017.05.006. Epub 2017 
      May 8.