PMID- 28621482
OWN - NLM
STAT- MEDLINE
DCOM- 20180417
LR  - 20180821
IS  - 2059-2310 (Electronic)
IS  - 2059-2302 (Linking)
VI  - 90
IP  - 3
DP  - 2017 Sep
TI  - Identification of 400 novel alleles at the HLA-A, -B, -C, -DRB1, -DQB1 loci from 
      China Marrow Donor Program.
PG  - 171-173
LID - 10.1111/tan.13071 [doi]
AB  - Four hundred novel human leukocyte antigen (HLA) alleles were identified in 
      Chinese individuals: 100 HLA-A alleles, 100 HLA-B alleles, 101 HLA-C alleles, 28 
      HLA-DRB1 alleles and 71 HLA-DQB1 alleles. Comparing novel alleles with their most 
      homologous allele, we found 72.73% non-synonymous nucleotide substitutions, 
      21.13% silent mutations, 3.90% nonsense mutations and 3.25% frameshift mutation. 
      352 (88%) of the 400 novel alleles are single nucleotide substitution variants 
      when compared with their most homologous alleles and other novel alleles differ 
      from their most similar allele by more than 1 nucleotide substitutions, such as 
      2, 3, 5, 6, 8 and so on. Some of the novel alleles are characterized by long 
      deletions or insertions, for example there is 23 bp deletion in the B*58:31N 
      allele when compared to its most homologous allele B*58:01:01:01.
CI  - (c) 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
FAU - Chai, X
AU  - Chai X
AUID- ORCID: 0000-0001-9476-6426
AD  - BGI Shenzhen, Shenzhen, China.
FAU - Zhang, H
AU  - Zhang H
AD  - BGI Shenzhen, Shenzhen, China.
FAU - Yang, X
AU  - Yang X
AD  - BGI Shenzhen, Shenzhen, China.
FAU - Yang, F
AU  - Yang F
AD  - BGI Shenzhen, Shenzhen, China.
FAU - Liu, N
AU  - Liu N
AD  - BGI Shenzhen, Shenzhen, China.
LA  - eng
PT  - Journal Article
DEP - 20170616
PL  - England
TA  - HLA
JT  - HLA
JID - 101675570
RN  - 0 (HLA-A Antigens)
RN  - 0 (HLA-B Antigens)
RN  - 0 (HLA-B58)
RN  - 0 (HLA-C Antigens)
RN  - 0 (HLA-DQ Antigens)
RN  - 0 (HLA-DQ1 antigen)
RN  - 0 (HLA-DRB1 Chains)
SB  - IM
MH  - *Alleles
MH  - China
MH  - Female
MH  - Genetic Loci
MH  - HLA-A Antigens/*genetics
MH  - HLA-B Antigens/*genetics
MH  - HLA-C Antigens/*genetics
MH  - HLA-DQ Antigens/*genetics
MH  - HLA-DRB1 Chains/*genetics
MH  - Humans
MH  - Male
MH  - Tissue Donors
OTO - NOTNLM
OT  - HLA-A
OT  - HLA-B
OT  - HLA-C
OT  - HLA-DQB1
OT  - HLA-DRB1
OT  - novel allele
EDAT- 2017/06/18 06:00
MHDA- 2018/04/18 06:00
CRDT- 2017/06/17 06:00
PHST- 2017/04/11 00:00 [received]
PHST- 2017/05/18 00:00 [revised]
PHST- 2017/05/22 00:00 [accepted]
PHST- 2017/06/18 06:00 [pubmed]
PHST- 2018/04/18 06:00 [medline]
PHST- 2017/06/17 06:00 [entrez]
AID - 10.1111/tan.13071 [doi]
PST - ppublish
SO  - HLA. 2017 Sep;90(3):171-173. doi: 10.1111/tan.13071. Epub 2017 Jun 16.