PMID- 28624007
OWN - NLM
STAT- MEDLINE
DCOM- 20180316
LR  - 20181202
IS  - 1872-7727 (Electronic)
IS  - 0720-048X (Linking)
VI  - 92
DP  - 2017 Jul
TI  - Cardiac MRI left ventricular global function index and quantitative late 
      gadolinium enhancement in unrecognized myocardial infarction.
PG  - 11-16
LID - S0720-048X(17)30156-0 [pii]
LID - 10.1016/j.ejrad.2017.04.012 [doi]
AB  - PURPOSE: To compare left ventricular global function index (LVGFI) and 
      quantitative late gadolinium enhancement (LGE) in patients with unrecognized 
      myocardial infarction (UMI), recognized myocardial infarction (RMI) and without 
      myocardial infarction (MI). MATERIAL AND METHODS: Under waiver of the 
      Institutional Review Board 235 patients (age 63.5+/-10.5years, 57 female) were 
      retrospectively evaluated. All patients had undergone cardiac MRI at 1.5T for 
      symptoms of CAD. 67 patients (29%) had suffered a known RMI before. Functional 
      imaging and full-intensity late gadolinium enhancement (LGE) imaging were 
      evaluated for LVGFI and quantitative LGE mass. RESULTS: Of 168 patients without 
      history of RMI, 48 patients (29%) had UMI, 120 patients had no MI. LVGFI was 
      lower in RMI patients (34+/-8% [range 16;52]), and UMI patients (35+/-8% [range 
      10;51]), compared to patients with no MI (38+/-7% [range 16;55]) respectively and 
      similar between RMI and UMI patients. RMI patients had full-intensity LGE in 
      11+/-6% of left ventricular myocardial mass (LVMM). UMI patients had LGE in 9+/-5% of 
      LVMM. RMI patients had significantly more LGE than UMI patients (p=0.0096). 
      CONCLUSION: LGE quantification is effective to assess infarction scar size in RMI 
      and UMI patients. LVGFI provides information on cardiac function and morphology 
      but does not allow for a reliable differentiation between patients with and 
      without history of MI, due small differences and wide overlap of LVGFI values for 
      all three patient groups. This may be a reason why LVGFI is not applied in 
      clinical routine.
CI  - Copyright (c) 2017. Published by Elsevier B.V.
FAU - Krumm, Patrick
AU  - Krumm P
AD  - Department of Diagnostic and Interventional Radiology, University of Tubingen, 
      Germany.
FAU - Zitzelsberger, Tanja
AU  - Zitzelsberger T
AD  - Department of Diagnostic and Interventional Radiology, University of Tubingen, 
      Germany. Electronic address: tanja.zitzelsberger@uni-tuebingen.de.
FAU - Weinmann, Melanie
AU  - Weinmann M
AD  - Department of Diagnostic and Interventional Radiology, University of Tubingen, 
      Germany.
FAU - Mangold, Stefanie
AU  - Mangold S
AD  - Department of Diagnostic and Interventional Radiology, University of Tubingen, 
      Germany.
FAU - Rath, Dominik
AU  - Rath D
AD  - Department of Internal Medicine III, Cardiology and Cardiovascular Medicine, 
      University of Tubingen, Germany.
FAU - Nikolaou, Konstantin
AU  - Nikolaou K
AD  - Department of Diagnostic and Interventional Radiology, University of Tubingen, 
      Germany.
FAU - Gawaz, Meinrad
AU  - Gawaz M
AD  - Department of Internal Medicine III, Cardiology and Cardiovascular Medicine, 
      University of Tubingen, Germany.
FAU - Kramer, Ulrich
AU  - Kramer U
AD  - Department of Diagnostic and Interventional Radiology, University of Tubingen, 
      Germany.
FAU - Klumpp, Bernhard Daniel
AU  - Klumpp BD
AD  - Department of Diagnostic and Interventional Radiology, University of Tubingen, 
      Germany.
LA  - eng
PT  - Journal Article
DEP - 20170417
PL  - Ireland
TA  - Eur J Radiol
JT  - European journal of radiology
JID - 8106411
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Cardiac Output
MH  - Cicatrix/pathology
MH  - Female
MH  - Gadolinium
MH  - Humans
MH  - Magnetic Resonance Imaging/*methods
MH  - Myocardial Infarction/*pathology
MH  - Retrospective Studies
OTO - NOTNLM
OT  - Infarction
OT  - Left
OT  - Magnetic resonance imaging
OT  - Myocardial infarction
OT  - Myocardium
OT  - Ventricular function
EDAT- 2017/06/19 06:00
MHDA- 2018/03/17 06:00
CRDT- 2017/06/19 06:00
PHST- 2016/08/14 00:00 [received]
PHST- 2017/04/08 00:00 [revised]
PHST- 2017/04/14 00:00 [accepted]
PHST- 2017/06/19 06:00 [entrez]
PHST- 2017/06/19 06:00 [pubmed]
PHST- 2018/03/17 06:00 [medline]
AID - S0720-048X(17)30156-0 [pii]
AID - 10.1016/j.ejrad.2017.04.012 [doi]
PST - ppublish
SO  - Eur J Radiol. 2017 Jul;92:11-16. doi: 10.1016/j.ejrad.2017.04.012. Epub 2017 Apr 
      17.