PMID- 28631812
OWN - NLM
STAT- MEDLINE
DCOM- 20180612
LR  - 20180612
IS  - 1365-4632 (Electronic)
IS  - 0011-9059 (Linking)
VI  - 56
IP  - 11
DP  - 2017 Nov
TI  - Identification of allergens by IgE-specific testing improves outcomes in atopic 
      dermatitis.
PG  - 1150-1153
LID - 10.1111/ijd.13673 [doi]
AB  - INTRODUCTION: IgE quantitative assaying of allergens (IgEQAA) has long been 
      implemented by allergists in determining patients' reactivities for allergic 
      rhinitis and asthma, two of the three diagnoses in atopic syndrome. This test 
      operates by measuring the patient's IgE response to different allergens and can 
      identify potential triggers for a patient's symptoms. Despite this, IgEQAA has 
      yet to see the same widespread use in the field of dermatology, specifically in 
      the treatment of patients with atopic dermatitis (AD). MATERIALS AND METHODS: The 
      affected body surface area (BSA) at first presentation, IgEQAA classes, and total 
      immunoglobulin E (IgE) concentration were taken retrospectively for 54 patients 
      with AD. RESULTS: Of the 54 patients observed, 41 had an abnormally high total 
      IgE concentration (76%). Additionally, it was observed that nine (17%) of our 
      patients significantly improved after making lifestyle changes. CONCLUSION: 
      Knowledge of the identified specific antigens can guide patients to make 
      lifestyle modifications that may improve disease outcomes. IgEQAA and avoidance 
      of allergens may help some patients with AD.
CI  - (c) 2017 The International Society of Dermatology.
FAU - Will, Brett M
AU  - Will BM
AD  - Georgetown University, School of Biomedical Graduate Education, Washington, DC, 
      USA.
FAU - Severino, Richard
AU  - Severino R
AD  - Biostatistician, The Queen's Medical Center, Honolulu, HI, USA.
FAU - Johnson, Douglas W
AU  - Johnson DW
AD  - University of Hawaii School of Medicine, Department of Medicine, Honolulu, HI, 
      USA.
LA  - eng
PT  - Journal Article
DEP - 20170620
PL  - England
TA  - Int J Dermatol
JT  - International journal of dermatology
JID - 0243704
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Animals
MH  - Body Surface Area
MH  - Child
MH  - Child, Preschool
MH  - Dander/*immunology
MH  - Dermatitis, Atopic/*immunology
MH  - Dermatophagoides farinae/*immunology
MH  - Dermatophagoides pteronyssinus/*immunology
MH  - Female
MH  - *Health Knowledge, Attitudes, Practice
MH  - Humans
MH  - Immunoglobulin E/*blood
MH  - Infant
MH  - Life Style
MH  - Male
MH  - Middle Aged
MH  - Pets/immunology
MH  - Radioallergosorbent Test
MH  - Retrospective Studies
MH  - Young Adult
EDAT- 2017/06/21 06:00
MHDA- 2018/06/13 06:00
CRDT- 2017/06/21 06:00
PHST- 2015/03/31 00:00 [received]
PHST- 2017/03/30 00:00 [revised]
PHST- 2017/05/03 00:00 [accepted]
PHST- 2017/06/21 06:00 [pubmed]
PHST- 2018/06/13 06:00 [medline]
PHST- 2017/06/21 06:00 [entrez]
AID - 10.1111/ijd.13673 [doi]
PST - ppublish
SO  - Int J Dermatol. 2017 Nov;56(11):1150-1153. doi: 10.1111/ijd.13673. Epub 2017 Jun 
      20.