PMID- 28636737
OWN - NLM
STAT- MEDLINE
DCOM- 20180405
LR  - 20190319
IS  - 1942-7522 (Electronic)
IS  - 0145-5613 (Linking)
VI  - 96
IP  - 6
DP  - 2017 Jun
TI  - Is there an association between migraine and allergic rhinitis?
PG  - E18-E23
AB  - We conducted a prospective study to evaluate nasal signs and symptoms and to 
      perform allergen-specific immunoglobulin E (IgE) testing to investigate the 
      relationship between migraine and allergic rhinitis. Our study group consisted of 
      40 patients diagnosed with migraine-22 men and 18 women, aged 21 to 38 years 
      (mean: 25.7). We compared their findings with a control group of 40 healthy 
      adults-15 men and 25 women, aged 19 to 36 years (mean: 25.1). Allergen-specific 
      IgE measurements were obtained with six groups of allergens: fungi, grass 
      pollens, tree pollens, wild herbs, house dust mite 1, and house dust mite 2. We 
      found no significant difference between the migraine patients and the controls in 
      the incidence of nasal signs and symptoms (i.e., discharge, congestion, itching, 
      and sneezing) or inferior turbinate signs (i.e., color and edema). According to 
      the IgE assays, 14 migraine patients (35.0%) were sensitized to one or more 
      allergens, compared with 11 of the controls (27.5%); the difference was not 
      statistically significant. Sensitization was highest for the grass pollens panel 
      in both groups. Even though we did not find an association between migraine and 
      allergic rhinitis, the recent literature supports a correlation between migraine 
      and atopy. The two conditions share common neural pathways and common mediators, 
      and they can be linked statistically in patients and their families. A 
      pathophysiologic association between the two conditions seems more likely than an 
      etiologic association. In this regard, future efforts could be focused on the 
      determination of atopy in migraine patients and the therapeutic implications of 
      this diagnosis.
FAU - Guvenc, Isil Adadan
AU  - Guvenc IA
AD  - ENT Department, Cigli Regional Training Hospital, Izmir, Turkey.
FAU - Acar, Mustafa
AU  - Acar M
FAU - Muluk, Nuray Bayar
AU  - Muluk NB
FAU - Kucukcan, Nagehan Erdogmus
AU  - Kucukcan NE
FAU - Cingi, Cemal
AU  - Cingi C
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Ear Nose Throat J
JT  - Ear, nose, & throat journal
JID - 7701817
RN  - 0 (Allergens)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adult
MH  - *Allergens/analysis/classification
MH  - Female
MH  - Humans
MH  - *Hypersensitivity, Immediate/diagnosis/immunology/physiopathology
MH  - Immunoglobulin E/*blood
MH  - Male
MH  - *Migraine Disorders/diagnosis/immunology
MH  - *Rhinitis, Allergic/diagnosis/immunology
MH  - Symptom Assessment
EDAT- 2017/06/22 06:00
MHDA- 2018/04/06 06:00
CRDT- 2017/06/22 06:00
PHST- 2017/06/22 06:00 [entrez]
PHST- 2017/06/22 06:00 [pubmed]
PHST- 2018/04/06 06:00 [medline]
AID - 10.1177/014556131709600604 [doi]
PST - ppublish
SO  - Ear Nose Throat J. 2017 Jun;96(6):E18-E23. doi: 10.1177/014556131709600604.