PMID- 28637033
OWN - NLM
STAT- MEDLINE
DCOM- 20180727
LR  - 20180828
IS  - 1421-976X (Electronic)
IS  - 0008-6568 (Linking)
VI  - 51
IP  - 4
DP  - 2017
TI  - Quantitative Swept-Source Optical Coherence Tomography of Early Enamel Erosion in 
      vivo.
PG  - 410-418
LID - 10.1159/000477098 [doi]
AB  - Swept-source optical coherence tomography (SS-OCT) shows potential for the in 
      vivo quantitative evaluation of micro-structural enamel surface phenomena 
      occurring during early erosive demineralization. This randomized controlled 
      single-blind cross-over clinical study aimed to evaluate the use of SS-OCT for 
      detecting optical changes in the enamel of 30 healthy volunteers subjected to 
      orange juice rinsing (erosive challenge) in comparison to mineral water rinsing 
      (control), according to wiped and non-wiped enamel surface states. Participants 
      were randomly allocated to 60 min of orange juice rinsing (pH 3.8) followed by 60 
      min of water rinsing (pH 6.7) and vice versa, with a 2-week wash-out period. In 
      addition, the labial surfaces of the right or left maxillary incisors were wiped 
      prior to SS-OCT imaging. An automated ImageJ algorithm was designed to analyse 
      the back-scattered OCT signal intensity (D) after orange juice rinsing compared 
      to after water rinsing. D was quantified as the OCT signal scattering from the 33 
      microm sub-surface enamel, normalised by the total OCT signal intensity entering the 
      enamel. The back-scattered OCT signal intensity increased by 3.1% (95% CI 
      1.1-5.1%) in the wiped incisors and by 3.5% (95% CI 1.5-5.5%) in the unwiped 
      incisors (p < 0.0001). Wiping reduced the back-scattered OCT signal intensity by 
      1.7% (95% CI -3.2 to -0.3%; p = 0.02) in comparison to the unwiped enamel 
      surfaces for both rinsing solutions (p = 0.2). SS-OCT detected OCT signal changes 
      in the superficial sub-surface enamel of maxillary central incisor teeth of 
      healthy volunteers after orange juice rinsing.
CI  - (c) 2017 S. Karger AG, Basel.
FAU - Austin, Rupert S
AU  - Austin RS
AD  - King's College London Dental Institute, Guy's, King's and St.Thomas' Hospitals, 
      London, UK.
FAU - Haji Taha, Maisalamah
AU  - Haji Taha M
FAU - Festy, Frederic
AU  - Festy F
FAU - Cook, Richard
AU  - Cook R
FAU - Andiappan, Manoharan
AU  - Andiappan M
FAU - Gomez, Juliana
AU  - Gomez J
FAU - Pretty, Iain A
AU  - Pretty IA
FAU - Moazzez, Rebecca
AU  - Moazzez R
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20170622
PL  - Switzerland
TA  - Caries Res
JT  - Caries research
JID - 0103374
SB  - IM
MH  - Adult
MH  - Cross-Over Studies
MH  - Dental Enamel/*diagnostic imaging/*pathology
MH  - Female
MH  - Humans
MH  - Male
MH  - Single-Blind Method
MH  - Tomography, Optical Coherence/*methods
MH  - Tooth Demineralization/*diagnostic imaging
MH  - Tooth Erosion/*diagnostic imaging
MH  - Young Adult
OTO - NOTNLM
OT  - Biophotonics
OT  - Optical coherence tomography
OT  - Salivary pellicle
OT  - Tooth wear
EDAT- 2017/06/22 06:00
MHDA- 2018/07/28 06:00
CRDT- 2017/06/22 06:00
PHST- 2016/11/24 00:00 [received]
PHST- 2017/04/26 00:00 [accepted]
PHST- 2017/06/22 06:00 [pubmed]
PHST- 2018/07/28 06:00 [medline]
PHST- 2017/06/22 06:00 [entrez]
AID - 000477098 [pii]
AID - 10.1159/000477098 [doi]
PST - ppublish
SO  - Caries Res. 2017;51(4):410-418. doi: 10.1159/000477098. Epub 2017 Jun 22.