PMID- 28637522
OWN - NLM
STAT- MEDLINE
DCOM- 20170731
LR  - 20240324
IS  - 1475-2662 (Electronic)
IS  - 0007-1145 (Linking)
VI  - 117
IP  - 11
DP  - 2017 Jun
TI  - Evaluation of urinary resveratrol as a biomarker of dietary resveratrol intake in 
      the European Prospective Investigation into Cancer and Nutrition (EPIC) study.
PG  - 1596-1602
LID - 10.1017/S0007114517001465 [doi]
AB  - In vitro studies have shown several beneficial properties of resveratrol. 
      Epidemiological evidence is still scarce, probably because of the difficulty in 
      estimating resveratrol exposure accurately. The current study aimed to assess the 
      relationships between acute and habitual dietary resveratrol and wine intake and 
      urinary resveratrol excretion in a European population. A stratified random 
      subsample of 475 men and women from four countries participating in the European 
      Prospective Investigation into Cancer and Nutrition (EPIC) cross-sectional study, 
      who had provided 24-h urine samples and completed a 24-h dietary recall (24-HDR) 
      on the same day, were included. Acute and habitual dietary data were collected 
      using standardised 24-HDR software and a validated country-specific dietary 
      questionnaire, respectively. Phenol-Explorer was used to estimate the intake of 
      resveratrol and other stilbenes. Urinary resveratrol was analysed using tandem 
      MS. Spearman's correlation coefficients between estimated dietary intakes of 
      resveratrol and other stilbenes and consumption of wine, their main food source, 
      were very high (r>0.9) when measured using dietary questionnaires and were 
      slightly lower with 24-HDR (r>0.8). Partial Spearman's correlations between 
      urinary resveratrol excretion and intake of resveratrol, total stilbenes or wine 
      were found to be higher when using the 24-HDR (R 2 partial approximately 0.6) 
      than when using the dietary questionnaires (R 2 partial approximately 0.5). 
      Moderate to high correlations between dietary resveratrol, total stilbenes and 
      wine, and urinary resveratrol concentrations were observed. These support the 
      earlier findings that 24-h urinary resveratrol is an effective biomarker of both 
      resveratrol and wine intakes. These correlations also support the validity of the 
      estimation of resveratrol intake using the dietary questionnaire and 
      Phenol-Explorer.
FAU - Zamora-Ros, Raul
AU  - Zamora-Ros R
AD  - 1Unit of Nutrition and Cancer,Epidemiology Research Program Catalan Institute of 
      Oncology,Bellvitge Biomedical Research Institute (IDIBELL),08908 Barcelona,Spain.
FAU - Rothwell, Joseph A
AU  - Rothwell JA
AD  - 2Section of Nutrition and Metabolism,International Agency for Research on Cancer 
      (IARC-WHO),69372 Lyon,France.
FAU - Achaintre, David
AU  - Achaintre D
AD  - 2Section of Nutrition and Metabolism,International Agency for Research on Cancer 
      (IARC-WHO),69372 Lyon,France.
FAU - Ferrari, Pietro
AU  - Ferrari P
AD  - 2Section of Nutrition and Metabolism,International Agency for Research on Cancer 
      (IARC-WHO),69372 Lyon,France.
FAU - Boutron-Ruault, Marie-Christine
AU  - Boutron-Ruault MC
AD  - 3Centre de recherche en epidemiologie et sante des populations (CESP),Institut 
      National de la Sante et de la Recherche Medicale (INSERM),Universite de 
      Versailles Saint-Quentin-en-Yvelines (UVSQ),Universite Paris-Sud,Universite 
      Paris-Saclay,94805 Villejuif,France.
FAU - Mancini, Francesca R
AU  - Mancini FR
AD  - 3Centre de recherche en epidemiologie et sante des populations (CESP),Institut 
      National de la Sante et de la Recherche Medicale (INSERM),Universite de 
      Versailles Saint-Quentin-en-Yvelines (UVSQ),Universite Paris-Sud,Universite 
      Paris-Saclay,94805 Villejuif,France.
FAU - Affret, Aurelie
AU  - Affret A
AD  - 3Centre de recherche en epidemiologie et sante des populations (CESP),Institut 
      National de la Sante et de la Recherche Medicale (INSERM),Universite de 
      Versailles Saint-Quentin-en-Yvelines (UVSQ),Universite Paris-Sud,Universite 
      Paris-Saclay,94805 Villejuif,France.
FAU - Kuhn, Tilman
AU  - Kuhn T
AD  - 5Division of Cancer Epidemiology,German Cancer Research Center,69120 
      Heidelberg,Germany.
FAU - Katzke, Verena
AU  - Katzke V
AD  - 5Division of Cancer Epidemiology,German Cancer Research Center,69120 
      Heidelberg,Germany.
FAU - Boeing, Heiner
AU  - Boeing H
AD  - 6Department of Epidemiology,German Institute of Human Nutrition 
      Potsdam-Rehbruecke,14558 Nuthetal,Germany.
FAU - Kuppel, Sven
AU  - Kuppel S
AD  - 6Department of Epidemiology,German Institute of Human Nutrition 
      Potsdam-Rehbruecke,14558 Nuthetal,Germany.
FAU - Trichopoulou, Antonia
AU  - Trichopoulou A
AD  - 7Hellenic Health Foundation,GR-115 27, Athens,Greece.
FAU - Lagiou, Pagona
AU  - Lagiou P
AD  - 7Hellenic Health Foundation,GR-115 27, Athens,Greece.
FAU - La Vecchia, Carlo
AU  - La Vecchia C
AD  - 7Hellenic Health Foundation,GR-115 27, Athens,Greece.
FAU - Palli, Domenico
AU  - Palli D
AD  - 11Cancer Risk Factors and Life-Style Epidemiology Unit,Cancer Research and 
      Prevention Institute (ISPO),50141 Florence,Italy.
FAU - Contiero, Paolo
AU  - Contiero P
AD  - 12Environmental Epidemiology Unit,Fondazione IRCCS (Istituto di Ricovero e Cura a 
      Carattere Scientifico) Istituto Nazionale dei Tumori,20133 Milan,Italy.
FAU - Panico, Salvatore
AU  - Panico S
AD  - 13Dipartimento di Medicina Clinica e Chirurgia,Federico II University,80131 
      Naples,Italy.
FAU - Tumino, Rosario
AU  - Tumino R
AD  - 14Cancer Registry and Histopathology Unit,'Civic M.P. Arezzo' Hospital,97100 
      Ragusa,Italy.
FAU - Ricceri, Fulvio
AU  - Ricceri F
AD  - 15Unit of Epidemiology,Regional Health Service ASL TO3,Grugliasco (TO),10093 
      Turin,Italy.
FAU - Noh, Hwayoung
AU  - Noh H
AUID- ORCID: 0000-0002-6978-8364
AD  - 2Section of Nutrition and Metabolism,International Agency for Research on Cancer 
      (IARC-WHO),69372 Lyon,France.
FAU - Freisling, Heinz
AU  - Freisling H
AD  - 2Section of Nutrition and Metabolism,International Agency for Research on Cancer 
      (IARC-WHO),69372 Lyon,France.
FAU - Romieu, Isabelle
AU  - Romieu I
AD  - 2Section of Nutrition and Metabolism,International Agency for Research on Cancer 
      (IARC-WHO),69372 Lyon,France.
FAU - Scalbert, Augustin
AU  - Scalbert A
AD  - 2Section of Nutrition and Metabolism,International Agency for Research on Cancer 
      (IARC-WHO),69372 Lyon,France.
LA  - eng
GR  - 001/WHO_/World Health Organization/International
PT  - Evaluation Study
PT  - Journal Article
DEP - 20170622
PL  - England
TA  - Br J Nutr
JT  - The British journal of nutrition
JID - 0372547
RN  - 0 (Biomarkers)
RN  - 0 (Phenols)
RN  - 0 (Stilbenes)
RN  - Q369O8926L (Resveratrol)
SB  - IM
MH  - Biomarkers/*urine
MH  - Cross-Sectional Studies
MH  - *Diet
MH  - Diet Surveys
MH  - Europe
MH  - *Feeding Behavior
MH  - Female
MH  - Humans
MH  - Male
MH  - Mental Recall
MH  - Middle Aged
MH  - Phenols/*urine
MH  - Prospective Studies
MH  - Resveratrol
MH  - Stilbenes/*administration & dosage/urine
MH  - *Wine
OTO - NOTNLM
OT  - 24-HDR 24-h dietary recall
OT  - DQ dietary questionnaire
OT  - Biomarkers
OT  - Intakes
OT  - Resveratrol
OT  - Urine
OT  - Wine
EDAT- 2017/06/24 06:00
MHDA- 2017/08/02 06:00
CRDT- 2017/06/23 06:00
PHST- 2017/06/24 06:00 [pubmed]
PHST- 2017/08/02 06:00 [medline]
PHST- 2017/06/23 06:00 [entrez]
AID - S0007114517001465 [pii]
AID - 10.1017/S0007114517001465 [doi]
PST - ppublish
SO  - Br J Nutr. 2017 Jun;117(11):1596-1602. doi: 10.1017/S0007114517001465. Epub 2017 
      Jun 22.