PMID- 28640642 OWN - NLM STAT- MEDLINE DCOM- 20180416 LR - 20181202 IS - 1525-6006 (Electronic) IS - 1064-1963 (Linking) VI - 39 IP - 7 DP - 2017 TI - Epidemiological characteristics of hyperhomocysteinemia and H-type hypertension in the elderly in Beijing, China. PG - 640-644 LID - 10.1080/10641963.2017.1306540 [doi] AB - Hyperhomocysteinemia (HHcy) is an important risk factor for atherosclerosis-related diseases, and H-type hypertension (HHT) is becoming a major health-care concern in China. We assessed the prevalence of HHcy and HHT in the elderly in a retrospective study based on data obtained from the Beijing Longitudinal Study of Aging. This cross-sectional study comprised 1460 people in the general population (638 males and 822 females) aged >/=60 years dwelling in an urban district, a suburb, and an outer suburb of Beijing in 2012. Statistical sampling techniques included cluster, stratification, and random selection. Basic information and physical examination data were collected by trained staff, and the levels of plasma homocysteine (Hcy) were measured. Our results showed that the mean concentration of plasma Hcy was 21.3 mumol/L in the elderly population (24.2 mumol/L for males and 19.0 mumol/L for females; 22.5 mumol/L for rural residents and 20.4 mumol/L for urban residents); 74.4% of the subjects were considered to have HHcy (86.2% of males and 63.8% of females; 75.8% of rural and 73.0% of urban residents), and 50.2% were considered to have HHT (55.2% of males and 45.7% of females; 51.8% of rural and 48.8% of urban residents). Our study findings indicated that the prevalence of HHcy and HHT was high among elderly persons in Beijing. FAU - Ma, Lina AU - Ma L AUID- ORCID: 0000-0001-7630-6960 AD - a Department of Geriatrics , Xuan Wu Hospital, Capital Medical University , Beijing , China. AD - b Department of Epidemiology and Social Medicine , Xuan Wu Hospital, Capital Medical University, Key Laboratory for Neurodegenerative Disease of Ministry of Education, Center of Alzheimer's Disease, Beijing Institute for Brain Disorders , Beijing , China. FAU - Li, Li AU - Li L AD - b Department of Epidemiology and Social Medicine , Xuan Wu Hospital, Capital Medical University, Key Laboratory for Neurodegenerative Disease of Ministry of Education, Center of Alzheimer's Disease, Beijing Institute for Brain Disorders , Beijing , China. AD - c Department of Geriatrics , Beijing Geriatric Hospital , Beijing , China. FAU - Tang, Zhe AU - Tang Z AD - b Department of Epidemiology and Social Medicine , Xuan Wu Hospital, Capital Medical University, Key Laboratory for Neurodegenerative Disease of Ministry of Education, Center of Alzheimer's Disease, Beijing Institute for Brain Disorders , Beijing , China. LA - eng PT - Journal Article DEP - 20170622 PL - England TA - Clin Exp Hypertens JT - Clinical and experimental hypertension (New York, N.Y. : 1993) JID - 9305929 RN - 0LVT1QZ0BA (Homocysteine) SB - IM MH - Aged MH - Beijing/epidemiology MH - China/epidemiology MH - Cross-Sectional Studies MH - Female MH - Homocysteine/metabolism MH - Humans MH - Hyperhomocysteinemia/blood/*epidemiology MH - Hypertension/*epidemiology/physiopathology MH - Longitudinal Studies MH - Male MH - Middle Aged MH - Prevalence MH - Retrospective Studies MH - Risk Factors MH - Rural Health MH - Urban Health OTO - NOTNLM OT - Elderly OT - H-type hypertension OT - epidemiology OT - hyperhomocysteinemia OT - prevalence EDAT- 2017/06/24 06:00 MHDA- 2018/04/17 06:00 CRDT- 2017/06/23 06:00 PHST- 2017/06/24 06:00 [pubmed] PHST- 2018/04/17 06:00 [medline] PHST- 2017/06/23 06:00 [entrez] AID - 10.1080/10641963.2017.1306540 [doi] PST - ppublish SO - Clin Exp Hypertens. 2017;39(7):640-644. doi: 10.1080/10641963.2017.1306540. Epub 2017 Jun 22.