PMID- 28645077
OWN - NLM
STAT- MEDLINE
DCOM- 20180423
LR  - 20181202
IS  - 1872-7123 (Electronic)
IS  - 0165-1781 (Linking)
VI  - 256
DP  - 2017 Oct
TI  - Increased blood BDNF in healthy individuals with a family history of depression.
PG  - 176-179
LID - S0165-1781(17)30509-7 [pii]
LID - 10.1016/j.psychres.2017.06.057 [doi]
AB  - The brain-derive neurotrophic factor (BDNF) may play an important role in the 
      course of depression. We aimed to study the associations between peripheral whole 
      blood BDNF levels in healthy individuals with and without a family history of 
      depression. BDNF levels were significantly increased in healthy individuals with 
      (n = 76), compared with healthy individuals without (n = 39) a family history of 
      depression and persisted after adjustment for age and gender differences. Higher 
      BDNF levels were associated with increasing age and seasonality. A family history 
      of depression may contribute to an elevation of peripheral BDNF levels in healthy 
      individuals.
CI  - Copyright (c) 2017 Elsevier B.V. All rights reserved.
FAU - Knorr, Ulla
AU  - Knorr U
AD  - Psychiatric Centre Copenhagen, Rigshospitalet, University Hospital of Copenhagen, 
      Denmark. Electronic address: ulla.knorr@regionh.dk.
FAU - Sondergaard, Mia H Greisen
AU  - Sondergaard MHG
AD  - Laboratory of Neuropsychiatry, University Hospital of Copenhagen, Rigshospitalet 
      and University of Copenhagen, Denmark.
FAU - Koefoed, Pernille
AU  - Koefoed P
AD  - Laboratory of Neuropsychiatry, University Hospital of Copenhagen, Rigshospitalet 
      and University of Copenhagen, Denmark.
FAU - Jorgensen, Anders
AU  - Jorgensen A
AD  - Psychiatric Centre Copenhagen, Rigshospitalet, University Hospital of Copenhagen, 
      Denmark; Laboratory of Neuropsychiatry, University Hospital of Copenhagen, 
      Rigshospitalet and University of Copenhagen, Denmark.
FAU - Faurholt-Jepsen, Maria
AU  - Faurholt-Jepsen M
AD  - Psychiatric Centre Copenhagen, Rigshospitalet, University Hospital of Copenhagen, 
      Denmark.
FAU - Vinberg, Maj
AU  - Vinberg M
AD  - Psychiatric Centre Copenhagen, Rigshospitalet, University Hospital of Copenhagen, 
      Denmark.
FAU - Kessing, Lars Vedel
AU  - Kessing LV
AD  - Psychiatric Centre Copenhagen, Rigshospitalet, University Hospital of Copenhagen, 
      Denmark.
LA  - eng
PT  - Journal Article
DEP - 20170617
PL  - Ireland
TA  - Psychiatry Res
JT  - Psychiatry research
JID - 7911385
RN  - 0 (Brain-Derived Neurotrophic Factor)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Brain-Derived Neurotrophic Factor/*blood
MH  - Depression/*blood/genetics
MH  - Depressive Disorder/*blood/genetics
MH  - Family
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Sex Factors
MH  - Young Adult
EDAT- 2017/06/24 06:00
MHDA- 2018/04/24 06:00
CRDT- 2017/06/24 06:00
PHST- 2017/03/24 00:00 [received]
PHST- 2017/06/14 00:00 [revised]
PHST- 2017/06/15 00:00 [accepted]
PHST- 2017/06/24 06:00 [pubmed]
PHST- 2018/04/24 06:00 [medline]
PHST- 2017/06/24 06:00 [entrez]
AID - S0165-1781(17)30509-7 [pii]
AID - 10.1016/j.psychres.2017.06.057 [doi]
PST - ppublish
SO  - Psychiatry Res. 2017 Oct;256:176-179. doi: 10.1016/j.psychres.2017.06.057. Epub 
      2017 Jun 17.