PMID- 28646442 OWN - NLM STAT- MEDLINE DCOM- 20180910 LR - 20181113 IS - 1970-9366 (Electronic) IS - 1828-0447 (Linking) VI - 12 IP - 7 DP - 2017 Oct TI - Variability of adverse events in the public health-care service of the Tuscany region. PG - 1033-1042 LID - 10.1007/s11739-017-1698-5 [doi] AB - The objective of the study is to analyze the variation of adverse events (AEs) according to the different structure of hospitals. The study is a multicenter, retrospective study. It involves 4 teaching hospitals (THs) and 32 community hospitals, distributed in 12 local trusts (LTs), of the Tuscany Regional Healthcare Service (RHS). A random sample of the clinical records of patients admitted in LTs and THs in 2008 was selected from the database of the hospital discharge records of the centers. Among 11,293 clinical records included, a total of 354 adverse events were identified. There was a significant higher incidence of AEs in the male and elderly (>65 years) population, and the incidence of AEs was more relevant in the THs (5.3, 95% CI 4.7-6.1) than in the LTs (1.8, 95% CI 1.5-2.2). AEs related to falls were significantly more preventable in THs (OR 19.22, 95% CI 2.45-151.02), while in LTs, AEs related to infections were the most preventable (OR 6.22, 95% CI 1.35-28.67). Concerning the consequence of AE, death is significantly more probable for AEs related to unexpected cardiac arrest in LTs, while disability and prolongation of the stay are significantly more probable consequences associated with re-admission in THs, and to transfer to ICU or HDU in LTs. Re-interventions, surgical complications and falls are the factors more correlated with AEs. In conclusion, the study shows a higher risk of incurring adverse events for the THs compared to the LTs, presumably connected with a major complexity of the clinical cases. Furthermore, the preventability of AEs is higher in the LTs (56.1 vs 42.2%), and this might be associated with lower expertise in managing complications in these settings. Concerning specialties, there are no significant differences in AEs distribution. FAU - Albolino, Sara AU - Albolino S AD - Centre for Clinical Risk Management and Patient Safety, Tuscany Region, Villa La Quiete alle Montalve, Via Pietro Dazzi, 1, 50141, Florence, Italy. albolinos@aou-careggi.toscana.it. FAU - Tartaglia, Riccardo AU - Tartaglia R AD - Centre for Clinical Risk Management and Patient Safety, Tuscany Region, Villa La Quiete alle Montalve, Via Pietro Dazzi, 1, 50141, Florence, Italy. FAU - Bellandi, Tommaso AU - Bellandi T AD - Centre for Clinical Risk Management and Patient Safety, Tuscany Region, Villa La Quiete alle Montalve, Via Pietro Dazzi, 1, 50141, Florence, Italy. FAU - Bianchini, Elisa AU - Bianchini E AD - Institute for Cancer Prevention, Florence, Italy. FAU - Fabbro, Giancarlo AU - Fabbro G AD - Institute for Cancer Prevention, Florence, Italy. FAU - Forni, Silvia AU - Forni S AD - Regional Agency for Quality in Healthcare, Florence, Italy. FAU - Cernuschi, Giulia AU - Cernuschi G AD - Department of Medicine, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Universita degli studi di Milano, Milan, Italy. FAU - Biggeri, Annibale AU - Biggeri A AD - Institute for Cancer Prevention, Florence, Italy. LA - eng GR - CUP E35J09000030001/Ministero della Salute/ PT - Journal Article PT - Multicenter Study DEP - 20170623 PL - Italy TA - Intern Emerg Med JT - Internal and emergency medicine JID - 101263418 SB - IM MH - Adult MH - Aged MH - Female MH - Humans MH - *Incidence MH - Italy MH - Length of Stay/statistics & numerical data MH - Male MH - Medical Errors/*classification/statistics & numerical data MH - Middle Aged MH - Patient Safety/standards/statistics & numerical data MH - Public Health/*standards/statistics & numerical data MH - Retrospective Studies OTO - NOTNLM OT - Adverse events OT - Clinical risk OT - Clinical settings OT - Patient safety OT - Retrospective record review EDAT- 2017/06/25 06:00 MHDA- 2018/09/11 06:00 CRDT- 2017/06/25 06:00 PHST- 2017/01/02 00:00 [received] PHST- 2017/06/13 00:00 [accepted] PHST- 2017/06/25 06:00 [pubmed] PHST- 2018/09/11 06:00 [medline] PHST- 2017/06/25 06:00 [entrez] AID - 10.1007/s11739-017-1698-5 [pii] AID - 10.1007/s11739-017-1698-5 [doi] PST - ppublish SO - Intern Emerg Med. 2017 Oct;12(7):1033-1042. doi: 10.1007/s11739-017-1698-5. Epub 2017 Jun 23.