PMID- 28647834
OWN - NLM
STAT- MEDLINE
DCOM- 20180905
LR  - 20181202
IS  - 1867-108X (Electronic)
IS  - 1867-1071 (Linking)
VI  - 35
IP  - 9
DP  - 2017 Sep
TI  - Influence of multi-leaf collimator leaf transmission on head and neck 
      intensity-modulated radiation therapy and volumetric-modulated arc therapy 
      planning.
PG  - 511-525
LID - 10.1007/s11604-017-0661-8 [doi]
AB  - The aim of this study was to quantify the effect of multi-leaf collimators (MLCs) 
      with different leaf widths on the planning of intensity-modulated radiation 
      therapy (IMRT) and volumetric-modulated arc therapy (VMAT). Toward this 
      objective, dose transmission through a high-definition 120-leaf MLC (HD120MLC) 
      and 120-leaf Millennium MLC (M120MLC) was investigated, using it with a test case 
      and clinical case studies. In test case, studies with IMRT and VMAT plans, the 
      difference in MLC leaf width had a limited effect on planning target volumes 
      (PTVs). Organs at risk (OARs) were more affected by a reduction in dose 
      transmission through the MLC than by a reduction in MLC leaf width. The results 
      of the test case studies and clinical case studies were mostly similar. In the 
      latter, the different MLCs had no effect on the PTV regardless of the treatment 
      method; however, the HD120MLC plans achieved dose reductions to OARs similar to 
      or larger than the dose reduction of the M120MLC plans. The similar results of 
      the test case and clinical case studies showed that despite a limitation of the 
      irradiation field size, the HD120MLC plans were superior.
FAU - Sasaki, Motoharu
AU  - Sasaki M
AD  - Department of Radiological Technology, Tokushima University Hospital, 2-50-1 
      Kuramoto-cho, Tokushima, Tokushima, 770-8503, Japan.
FAU - Tominaga, Masahide
AU  - Tominaga M
AD  - Department of Therapeutic Radiology, Institute of Biomedical Sciences, Tokushima 
      University Graduate School, 3-18-15 Kuramoto-cho, Tokushima, Tokushima, 770-8503, 
      Japan. tominaga@tokushima-u.ac.jp.
FAU - Kamomae, Takeshi
AU  - Kamomae T
AD  - Department of Therapeutic Radiology, Nagoya University Graduate School of 
      Medicine, 65 Tsurumai, Showa-ku, Nagoya, Aichi, 466-8550, Japan.
FAU - Ikushima, Hitoshi
AU  - Ikushima H
AD  - Department of Therapeutic Radiology, Institute of Biomedical Sciences, Tokushima 
      University Graduate School, 3-18-15 Kuramoto-cho, Tokushima, Tokushima, 770-8503, 
      Japan.
FAU - Kitaoka, Motonori
AU  - Kitaoka M
AD  - Department of Radiological Technology, Kagawa University Hospital, 1750-1 
      Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
FAU - Bando, Ryota
AU  - Bando R
AD  - Department of Radiological Technology, Tokushima University Hospital, 2-50-1 
      Kuramoto-cho, Tokushima, Tokushima, 770-8503, Japan.
FAU - Sakuragawa, Kanako
AU  - Sakuragawa K
AD  - Department of Radiological Technology, Tokushima University Hospital, 2-50-1 
      Kuramoto-cho, Tokushima, Tokushima, 770-8503, Japan.
FAU - Oita, Masataka
AU  - Oita M
AD  - Department of Radiological Technology, Graduate School of Health Sciences, 
      Okayama University, 2-5-1 Shikata-cho, Okayama Kita-ku, Okayama, 700-8558, Japan.
LA  - eng
PT  - Journal Article
DEP - 20170624
PL  - Japan
TA  - Jpn J Radiol
JT  - Japanese journal of radiology
JID - 101490689
SB  - IM
MH  - Head and Neck Neoplasms/*radiotherapy
MH  - Humans
MH  - Organs at Risk
MH  - Radiotherapy Dosage
MH  - Radiotherapy Planning, Computer-Assisted/instrumentation/*methods
MH  - Radiotherapy, Intensity-Modulated/*methods
OTO - NOTNLM
OT  - Head and neck cancer
OT  - Intensity-modulated radiation therapy
OT  - Multi-leaf collimator
OT  - Volumetric-modulated arc therapy
EDAT- 2017/06/26 06:00
MHDA- 2018/09/06 06:00
CRDT- 2017/06/26 06:00
PHST- 2016/08/15 00:00 [received]
PHST- 2017/06/13 00:00 [accepted]
PHST- 2017/06/26 06:00 [pubmed]
PHST- 2018/09/06 06:00 [medline]
PHST- 2017/06/26 06:00 [entrez]
AID - 10.1007/s11604-017-0661-8 [pii]
AID - 10.1007/s11604-017-0661-8 [doi]
PST - ppublish
SO  - Jpn J Radiol. 2017 Sep;35(9):511-525. doi: 10.1007/s11604-017-0661-8. Epub 2017 
      Jun 24.