PMID- 28648416 OWN - NLM STAT- MEDLINE DCOM- 20180411 LR - 20220318 IS - 2213-3763 (Electronic) IS - 0019-4832 (Print) IS - 0019-4832 (Linking) VI - 69 IP - 3 DP - 2017 May-Jun TI - Primary percutaneous coronary intervention for acute ST elevation myocardial infarction: Outcomes and determinants of outcomes: A tertiary care center study from North India. PG - 294-298 LID - S0019-4832(16)30093-1 [pii] LID - 10.1016/j.ihj.2016.11.322 [doi] AB - BACKGROUND: Primary percutaneous coronary intervention (PCI) is the current standard of care for acute ST elevation myocardial infarction (STEMI). Most of the data on primary PCI in acute STEMI is from western countries. We studied the outcomes of primary PCI for acute STEMI at a tertiary care center in North India. METHODS: Consecutive patients undergoing primary PCI for STEMI were prospectively studied during the period from February 2103 to May 2015. The outcomes assessed were all cause in hospital mortality, factors associated with mortality, major adverse cardiac and cerebrovascular event rate (composite of all cause in hospital mortality, non-fatal re infarction and stroke) and procedural complications. RESULTS: 371 patients underwent primary PCI during the study period. The mean age was 54 years and 82.7% were males. The mean total ischemia time and door to balloon times were 6.8h and 51min respectively. 96.4% patients underwent successful primary PCI. The total in hospital mortality was 12.9%. Mortality with cardiogenic shock at presentation was 66.7% while non-shock mortality was 2.6%. In hospital MACCE rate was 13.5%. Factors significantly associated with mortality were KILLIP class (OR: 8.4), door to balloon time (OR 1.02), final TIMI flow (OR 0.44) and severe LV dysfunction (OR 22.0). Procedure related adverse events were rare and there was no non-CABG associated major TIMI bleeding. CONCLUSION: Primary PCI for acute STEMI is feasible in our setup and associated with high success rate, low mortality in non-shock patients and low complication rates. CI - Copyright (c) 2016. Published by Elsevier B.V. FAU - Dubey, Gajendra AU - Dubey G AD - Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India. Electronic address: gajendra.dubey119@gmail.com. FAU - Verma, Sunil Kumar AU - Verma SK AD - Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India. FAU - Bahl, Vinay Kumar AU - Bahl VK AD - Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India. LA - eng PT - Journal Article PT - Observational Study DEP - 20161130 PL - India TA - Indian Heart J JT - Indian heart journal JID - 0374675 SB - IM MH - Coronary Angiography MH - Electrocardiography MH - Female MH - Follow-Up Studies MH - Hospital Mortality/trends MH - Humans MH - Incidence MH - India/epidemiology MH - Male MH - Middle Aged MH - Percutaneous Coronary Intervention/*methods MH - Postoperative Complications/*epidemiology MH - Prospective Studies MH - Risk Factors MH - ST Elevation Myocardial Infarction/diagnosis/mortality/*surgery MH - Survival Rate/trends MH - *Tertiary Care Centers MH - Time Factors MH - Treatment Outcome PMC - PMC5485382 OTO - NOTNLM OT - Cardiogenic shock OT - Door to balloon time OT - KILLIP class OT - Primary PCI OT - STEMI OT - Total ischemia time EDAT- 2017/06/27 06:00 MHDA- 2018/04/12 06:00 PMCR- 2018/05/01 CRDT- 2017/06/27 06:00 PHST- 2016/05/01 00:00 [received] PHST- 2016/10/30 00:00 [revised] PHST- 2016/11/17 00:00 [accepted] PHST- 2017/06/27 06:00 [entrez] PHST- 2017/06/27 06:00 [pubmed] PHST- 2018/04/12 06:00 [medline] PHST- 2018/05/01 00:00 [pmc-release] AID - S0019-4832(16)30093-1 [pii] AID - 10.1016/j.ihj.2016.11.322 [doi] PST - ppublish SO - Indian Heart J. 2017 May-Jun;69(3):294-298. doi: 10.1016/j.ihj.2016.11.322. Epub 2016 Nov 30.