PMID- 28658040
OWN - NLM
STAT- MEDLINE
DCOM- 20190603
LR  - 20210115
IS  - 1528-1159 (Electronic)
IS  - 0362-2436 (Linking)
VI  - 42
IP  - 24
DP  - 2017 Dec 15
TI  - Minimal Clinically Important Difference in Quality of Life for Patients With Low 
      Back Pain.
PG  - 1908-1916
LID - 10.1097/BRS.0000000000002298 [doi]
AB  - STUDY DESIGN: Multicenter, prospective, cohort study. OBJECTIVE: To estimate the 
      Minimal Clinically Important Difference (MCID) for the physical (PCS) and mental 
      (MCS) component summaries of Short Form SF-12 (SF-12), in patients with low back 
      pain (LBP). SUMMARY OF BACKGROUND DATA: Quality of life is one of the core 
      domains recommended to be assessed in patients with LBP. SF-12 is the most widely 
      used instrument for this purpose, but its MCID was unknown. METHODS: A total of 
      458 patients with subacute and chronic LBP were consecutively recruited across 21 
      practices. LBP, referred pain, disability, PCS, and MCS were assessed upon 
      recruitment and 12 months later. Self-reported health status change between 
      baseline and 12 month-assessment, was used as the external criterion. The MCID 
      for SF-12 was estimated following four anchor-based methods; minimal detectable 
      change (MDC); average change (AC); change difference (CD); and receiver operating 
      characteristic curve (ROC), for which the area under the curve (AUC) was 
      calculated. The effect on MCID values of pain duration and baseline scores was 
      assessed. RESULTS: Values for PCS were: MDC: 0.56, AC: 2.71, CD: 3.29, and ROC: 
      1.14. Values for MCS were: MDC: 3.77, AC: 3.54, CD: 1.13, and ROC: 4.23. AUC 
      values were <0.7; MCID values were smaller among chronic patients and those with 
      better baseline quality of life. CONCLUSION: Different methods for MCID 
      calculation lead to different results. In patients with subacute and chronic LBP, 
      improvements >3.77 in MCS and >3.29 in PCS, can be considered clinically 
      relevant. MCID is smaller in patients with longer pain duration and better 
      baseline quality of life. LEVEL OF EVIDENCE: 2.
FAU - Diaz-Arribas, Maria J
AU  - Diaz-Arribas MJ
AD  - Physical Medicine and Rehabilitation Department, Faculty of Medicine, Complutense 
      University, Madrid, Spain.
AD  - Spanish Back Pain Research Network.
FAU - Fernandez-Serrano, Monica
AU  - Fernandez-Serrano M
AD  - Spanish Back Pain Research Network.
AD  - Nurse and Physical Therapy Department. University of Alcala, Alcala de Henares, 
      Spain.
AD  - Physical Therapy Research Group in Primary Care.
FAU - Royuela, Ana
AU  - Royuela A
AD  - Spanish Back Pain Research Network.
AD  - Clinical Biostatistics Unit, Puerta de Hierro University Hospital, Instituto de 
      Investigacion Puerta de Hierro, Madrid, Spain.
FAU - Kovacs, Francisco M
AU  - Kovacs FM
AD  - Spanish Back Pain Research Network.
AD  - Kovacs Back Pain Unit. Moncloa University Hospital Avda. Valladolid, Madrid, 
      Spain.
AD  - Kovacs Research Institute, Madrid, Spain.
FAU - Gallego-Izquierdo, Tomas
AU  - Gallego-Izquierdo T
AD  - Nurse and Physical Therapy Department. University of Alcala, Alcala de Henares, 
      Spain.
AD  - Physical Therapy Research Group in Primary Care.
FAU - Ramos-Sanchez, Mabel
AU  - Ramos-Sanchez M
AD  - Physical Medicine and Rehabilitation Department, Faculty of Medicine, Complutense 
      University, Madrid, Spain.
AD  - Spanish Back Pain Research Network.
FAU - Llorca-Palomera, Rosa
AU  - Llorca-Palomera R
AD  - Physical Medicine and Rehabilitation Department, Faculty of Medicine, Complutense 
      University, Madrid, Spain.
AD  - Spanish Back Pain Research Network.
FAU - Pardo-Hervas, Pedro
AU  - Pardo-Hervas P
AD  - Physical Medicine and Rehabilitation Department, Faculty of Medicine, Complutense 
      University, Madrid, Spain.
AD  - Spanish Back Pain Research Network.
FAU - Martin-Pariente, Oscar S
AU  - Martin-Pariente OS
AD  - Spanish Back Pain Research Network.
AD  - Physical Therapy Research Group in Primary Care.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PL  - United States
TA  - Spine (Phila Pa 1976)
JT  - Spine
JID - 7610646
SB  - IM
MH  - Adult
MH  - Area Under Curve
MH  - Chronic Pain/therapy
MH  - *Conservative Treatment
MH  - Disability Evaluation
MH  - Female
MH  - Health Status
MH  - Humans
MH  - Low Back Pain/*therapy
MH  - Male
MH  - Middle Aged
MH  - *Minimal Clinically Important Difference
MH  - Pain Measurement
MH  - Prospective Studies
MH  - *Quality of Life
MH  - ROC Curve
MH  - Self Report
MH  - Treatment Outcome
EDAT- 2017/06/29 06:00
MHDA- 2019/06/04 06:00
CRDT- 2017/06/29 06:00
PHST- 2017/06/29 06:00 [pubmed]
PHST- 2019/06/04 06:00 [medline]
PHST- 2017/06/29 06:00 [entrez]
AID - 00007632-201712150-00019 [pii]
AID - 10.1097/BRS.0000000000002298 [doi]
PST - ppublish
SO  - Spine (Phila Pa 1976). 2017 Dec 15;42(24):1908-1916. doi: 
      10.1097/BRS.0000000000002298.