PMID- 28658100
OWN - NLM
STAT- MEDLINE
DCOM- 20170717
LR  - 20210109
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 26
DP  - 2017 Jun
TI  - Echocardiography and Electrocardiography Variables Correlate With the New York 
      Heart Association classification: An Observational Study of Ischemic 
      Cardiomyopathy Patients.
PG  - e7071
LID - 10.1097/MD.0000000000007071 [doi]
LID - e7071
AB  - The aim of our study was to determine whether combinations of ultrasound 
      echocardiography (UCG) and electrocardiography (EKG) parameters correlated with 
      the functional status of ischemic cardiomyopathy (ICM) patients according to the 
      New York Heart Association (NYHA) classification system.We assessed 536 elderly 
      Chinese ICM patients according to the NYHA criteria, which included 196 patients 
      with type 2 diabetes mellitus (T2DM). All of the patients underwent UCG. 
      Transmural dispersion of ventricular repolarization was examined using EKG. 
      Cumulative odds logistic regression was performed to evaluate associations 
      between NYHA class and the demographic, clinical, UCG, and EKG variables based on 
      the odds ratio (OR) and 95% confidence interval (CI). A Pearson analysis was also 
      performed to examine correlations between the NYHA classification and the UCG and 
      EKG variables.Based on the NYHA assessment, 140, 147, 138, and 111 patients were 
      identified as class I, II, III and IV, respectively. A comparison of UCG and EKG 
      variables based on T2DM status showed that CO and Tp-e differed significantly 
      between all NYHA classes (P < .05 for all), with values of each increasing with 
      increasing NYHA class regardless of T2DM status. Multivariate logistic regression 
      analysis showed that the disease course (OR: 1.30; 95% CI: 1.20-1.40), heart rate 
      (OR: 1.16; 95% CI: 1.12-1.21), T wave peak to endpoint (Tp-e; OR: 1.22; 95% CI: 
      1.18-1.27), dispersion of the QT interval (OR: 0.98; 95% CI: 0.95-1.22), left 
      ventricular fractional shortening (OR: 0.82; 95% CI: 0.78-0.87), cardiac output 
      (CO; OR: 5.58; 95% CI: 3.08-10.13) were significantly associated with the NYHA 
      class (P < .0001 for all). A Pearson correlation analysis showed that Tp-e 
      (r = 0.75982, P < .0001), CO (r = 0.56072, P < .0001), and stroke volume 
      (r = -0.14839, P = .0006) significantly correlated with the NYHA class.An index 
      consisting of Tp-e and CO will be useful for corroborating the results of the 
      NYHA assessment of ICM patients.
FAU - Hu, Ying
AU  - Hu Y
AD  - Department of Geriatrics, Xuhui District Central Hospital Department of 
      Geriatrics, Qingpu Branch of Zhongshan Hospital, Fudan University Geriatric 
      Nursing Services, Xuhui District Tianlin Street Community Health Service Center 
      General, Shanghai, China.
FAU - Jiang, Shifeng
AU  - Jiang S
FAU - Lu, Siyuan
AU  - Lu S
FAU - Xu, Rong
AU  - Xu R
FAU - Huang, Yunping
AU  - Huang Y
FAU - Zhao, Zongliang
AU  - Zhao Z
FAU - Qu, Yi
AU  - Qu Y
LA  - eng
PT  - Journal Article
PT  - Observational Study
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - IM
MH  - Aged
MH  - Body Mass Index
MH  - China
MH  - Diabetes Mellitus, Type 2/blood/complications/diagnostic imaging
MH  - *Echocardiography, Doppler, Color
MH  - *Electrocardiography
MH  - Female
MH  - Heart/*diagnostic imaging
MH  - Heart Rate
MH  - Humans
MH  - Logistic Models
MH  - Male
MH  - Multivariate Analysis
MH  - Myocardial Ischemia/blood/*classification/complications/*diagnostic imaging
PMC - PMC5500022
COIS- The authors report no conflicts of interest.
EDAT- 2017/06/29 06:00
MHDA- 2017/07/18 06:00
PMCR- 2017/06/30
CRDT- 2017/06/29 06:00
PHST- 2017/06/29 06:00 [entrez]
PHST- 2017/06/29 06:00 [pubmed]
PHST- 2017/07/18 06:00 [medline]
PHST- 2017/06/30 00:00 [pmc-release]
AID - 00005792-201706300-00008 [pii]
AID - MD-D-16-04683 [pii]
AID - 10.1097/MD.0000000000007071 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Jun;96(26):e7071. doi: 10.1097/MD.0000000000007071.