PMID- 28664557
OWN - NLM
STAT- MEDLINE
DCOM- 20180518
LR  - 20180518
IS  - 1540-8175 (Electronic)
IS  - 0742-2822 (Linking)
VI  - 34
IP  - 8
DP  - 2017 Aug
TI  - Effects of oxygen therapy on wall-motion score index in patients with ST 
      elevation myocardial infarction-the randomized SOCCER trial.
PG  - 1130-1137
LID - 10.1111/echo.13599 [doi]
AB  - BACKGROUND: Although oxygen (O(2) ) is routinely used in patients with acute 
      myocardial infarction (AMI), it may have negative effects. In this substudy of 
      the SOCCER trial, we aimed to evaluate the effects of O(2) -treatment on 
      myocardial function in patients with ST elevation myocardial infarction (STEMI). 
      METHODS: Normoxic (>/=94%) STEMI patients were randomized in the ambulance to 
      either supplemental O(2) or room air until the end of the percutaneous coronary 
      intervention (PCI). The patients underwent echocardiography on day 2-3 after the 
      PCI and once again after 6 months. The study endpoints were wall-motion score 
      index (WMSI) and left ventricular ejection fraction (LVEF). RESULTS: Forty-six 
      patients in the O(2) group and 41 in the air group were included in the analysis. 
      The index echocardiography showed no significant differences between the groups 
      in WMSI (1.32+/-0.27 for O(2) group vs 1.28+/-0.28 for air group) or LVEF (47.0+/-8.5% 
      vs 49.2+/-8.1%). Nor were there differences at 6 months in WMSI (1.16+/-0.25 vs 
      1.14+/-0.24) or LVEF (53.5+/-5.8% vs 53.5+/-6.9%). CONCLUSION: The present findings 
      indicate no harm or benefit of supplemental O(2) on myocardial function in STEMI 
      patients. Our results support that it is safe to withhold supplemental O(2) in 
      normoxic STEMI patients.
CI  - (c) 2017, Wiley Periodicals, Inc.
FAU - Khoshnood, Ardavan
AU  - Khoshnood A
AUID- ORCID: 0000-0002-3142-4119
AD  - Department of Clinical Sciences Lund, Emergency and Internal Medicine, Skane 
      University Hospital, Lund University, Lund, Sweden.
FAU - Akbarzadeh, Mahin
AU  - Akbarzadeh M
AD  - Department of Clinical Sciences Lund, Emergency and Internal Medicine, Skane 
      University Hospital, Lund University, Lund, Sweden.
FAU - Roijer, Anders
AU  - Roijer A
AD  - Department of Clinical Sciences Lund, Cardiology, Skane University Hospital, Lund 
      University, Lund, Sweden.
FAU - Meurling, Carl
AU  - Meurling C
AD  - Department of Clinical Sciences Lund, Cardiology, Skane University Hospital, Lund 
      University, Lund, Sweden.
FAU - Carlsson, Marcus
AU  - Carlsson M
AD  - Department of Clinical Sciences Lund, Clinical Physiology, Skane University 
      Hospital, Lund University, Lund, Sweden.
FAU - Bhiladvala, Pallonji
AU  - Bhiladvala P
AD  - Department of Cardiology, Skane University Hospital, Malmo, Sweden.
FAU - Hoglund, Peter
AU  - Hoglund P
AD  - Region Skane Research and Development Center, Lund, Sweden.
FAU - Sparv, David
AU  - Sparv D
AD  - Department of Clinical Sciences Lund, Cardiology, Skane University Hospital, Lund 
      University, Lund, Sweden.
FAU - Todorova, Lizbet
AU  - Todorova L
AD  - Region Skane Prehospital Unit, Lund, Sweden.
FAU - Mokhtari, Arash
AU  - Mokhtari A
AD  - Department of Clinical Sciences Lund, Emergency and Internal Medicine, Skane 
      University Hospital, Lund University, Lund, Sweden.
FAU - Erlinge, David
AU  - Erlinge D
AD  - Department of Clinical Sciences Lund, Cardiology, Skane University Hospital, Lund 
      University, Lund, Sweden.
FAU - Ekelund, Ulf
AU  - Ekelund U
AD  - Department of Clinical Sciences Lund, Emergency and Internal Medicine, Skane 
      University Hospital, Lund University, Lund, Sweden.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20170629
PL  - United States
TA  - Echocardiography
JT  - Echocardiography (Mount Kisco, N.Y.)
JID - 8511187
SB  - IM
MH  - Aged
MH  - Echocardiography/*methods
MH  - Electrocardiography
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Ventricles/diagnostic imaging/*physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Oxygen Inhalation Therapy/*methods
MH  - *Percutaneous Coronary Intervention
MH  - Retrospective Studies
MH  - ST Elevation Myocardial Infarction/diagnosis/physiopathology/*therapy
MH  - Single-Blind Method
MH  - Stroke Volume/*physiology
MH  - Time Factors
MH  - Treatment Outcome
MH  - Ventricular Function, Left/*physiology
OTO - NOTNLM
OT  - ST elevation myocardial infarction
OT  - cardiology
OT  - echocardiography
OT  - emergency medicine
OT  - oxygen therapy
EDAT- 2017/07/01 06:00
MHDA- 2018/05/19 06:00
CRDT- 2017/07/01 06:00
PHST- 2017/07/01 06:00 [pubmed]
PHST- 2018/05/19 06:00 [medline]
PHST- 2017/07/01 06:00 [entrez]
AID - 10.1111/echo.13599 [doi]
PST - ppublish
SO  - Echocardiography. 2017 Aug;34(8):1130-1137. doi: 10.1111/echo.13599. Epub 2017 
      Jun 29.