PMID- 28664820
OWN - NLM
STAT- MEDLINE
DCOM- 20180905
LR  - 20180905
IS  - 2048-8734 (Electronic)
IS  - 2048-8726 (Linking)
VI  - 7
IP  - 4
DP  - 2018 Jun
TI  - Ten thousand kilometre transfer of cardiogenic shock patients on venoarterial 
      extracorporeal membrane oxygenation for emergency heart transplantation: 
      Cooperation between Reunion Island and Metropolitan France.
PG  - 371-378
LID - 10.1177/2048872617719652 [doi]
AB  - BACKGROUND: There is no heart transplantation centre on the French overseas 
      territory of Reunion Island (distance of 10,000 km). The aim of this study was to 
      describe the characteristics of cardiogenic shock adult patients on venoarterial 
      extracorporeal membrane oxygenation (VA-ECMO) who were transferred from Reunion 
      Island to mainland France for emergency heart transplantation. METHODS: This 
      retrospective observational study was conducted between 2005 and 2015. The 
      characteristics and outcome of cardiogenic shock patients on VA-ECMO were 
      compared with those of cardiogenic shock patients not on VA-ECMO. RESULTS: 
      Thirty-three cardiogenic shock adult patients were transferred from Reunion 
      Island to Paris for emergency heart transplantation. Among them, 19 (57.6%) 
      needed mechanical circulatory support in the form of VA-ECMO. Median age was 51 
      (33-57) years and 46% of the patients had ischaemic heart disease. Patients on 
      VA-ECMO presented higher Sequential Organ Failure Assessment score ( p = 0.03). 
      No death occurred during the medical transfer by long flight, while severe 
      complications occurred in 10 patients (30.3%). Incidence of thromboembolic 
      events, severe infectious complications and major haemorrhages was higher in the 
      group of patients on VA-ECMO than in the group of patients not on VA-ECMO ( p 
      <0.01). Seven patients from the VA-ECMO group (36.8%) and six patients from the 
      non-VA-ECMO group (42.9%, p=0.7) underwent heart transplantation after a median 
      delay of 10 (4-29) days on the emergency waiting list. After heart 
      transplantation, one-year survival rates were 85.7% for patients on VA-ECMO and 
      83.3% for patients not on VA-ECMO ( p=0.91). CONCLUSIONS: This study suggests the 
      feasibility of very long-distance medical evacuation of cardiogenic shock 
      patients on VA-ECMO for emergency heart transplantation, with acceptable 
      long-term results.
FAU - Charon, Clement
AU  - Charon C
AD  - 1 Reanimation polyvalente, Centre Hospitalier Universitaire Felix Guyon, Saint 
      Denis, France.
FAU - Allyn, Jerome
AU  - Allyn J
AD  - 1 Reanimation polyvalente, Centre Hospitalier Universitaire Felix Guyon, Saint 
      Denis, France.
FAU - Bouchet, Bruno
AU  - Bouchet B
AD  - 1 Reanimation polyvalente, Centre Hospitalier Universitaire Felix Guyon, Saint 
      Denis, France.
FAU - Nativel, Frederic
AU  - Nativel F
AD  - 2 SAMU 974, Centre Hospitalier Universitaire Felix Guyon, Saint Denis, France.
FAU - Braunberger, Eric
AU  - Braunberger E
AD  - 3 Service de Chirurgie Cardiaque, Centre Hospitalier Universitaire Felix Guyon, 
      Saint Denis, France.
FAU - Brulliard, Caroline
AU  - Brulliard C
AD  - 1 Reanimation polyvalente, Centre Hospitalier Universitaire Felix Guyon, Saint 
      Denis, France.
FAU - Martinet, Olivier
AU  - Martinet O
AD  - 1 Reanimation polyvalente, Centre Hospitalier Universitaire Felix Guyon, Saint 
      Denis, France.
FAU - Allou, Nicolas
AU  - Allou N
AD  - 1 Reanimation polyvalente, Centre Hospitalier Universitaire Felix Guyon, Saint 
      Denis, France.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20170630
PL  - England
TA  - Eur Heart J Acute Cardiovasc Care
JT  - European heart journal. Acute cardiovascular care
JID - 101591369
SB  - IM
MH  - Adult
MH  - *Emergencies
MH  - Extracorporeal Membrane Oxygenation/*methods
MH  - Female
MH  - Follow-Up Studies
MH  - France/epidemiology
MH  - *Heart Transplantation
MH  - Hospital Mortality/trends
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Middle Aged
MH  - Patient Transfer/*methods
MH  - Retrospective Studies
MH  - Reunion/epidemiology
MH  - Shock, Cardiogenic/epidemiology/*therapy
MH  - Survival Rate/trends
OTO - NOTNLM
OT  - Heart transplantation
OT  - emergency
OT  - venoarterial extracorporeal membrane oxygenation
EDAT- 2017/07/01 06:00
MHDA- 2018/09/06 06:00
CRDT- 2017/07/01 06:00
PHST- 2017/07/01 06:00 [pubmed]
PHST- 2018/09/06 06:00 [medline]
PHST- 2017/07/01 06:00 [entrez]
AID - 10.1177/2048872617719652 [doi]
PST - ppublish
SO  - Eur Heart J Acute Cardiovasc Care. 2018 Jun;7(4):371-378. doi: 
      10.1177/2048872617719652. Epub 2017 Jun 30.