PMID- 28665885
OWN - NLM
STAT- MEDLINE
DCOM- 20180305
LR  - 20220330
IS  - 1473-5571 (Electronic)
IS  - 0269-9370 (Print)
IS  - 0269-9370 (Linking)
VI  - 31 Suppl 3
IP  - Suppl 3
DP  - 2017 Jul 1
TI  - The Metropolitan Atlanta community adolescent rapid testing initiative study: 
      closing the gaps in HIV care among youth in Atlanta, Georgia, USA.
PG  - S267-S275
LID - 10.1097/QAD.0000000000001512 [doi]
AB  - OBJECTIVE: To determine the effectiveness of the Metropolitan Atlanta community 
      adolescent rapid testing initiative (MACARTI) intervention relative to standard 
      of care (SOC), in achieving early diagnosis, linkage, and retention among 
      HIV-infected youth ages 18-24 years. DESIGN: MACARTI was a pilot single-center, 
      prospective, nonrandomized study. METHODS: MACARTI combined nontraditional venue 
      HIV testing, motivational interviewing, and case management. We collected 
      demographic, clinical variables and calculated linkage and appointment adherence 
      rates. We obtained SOC data from an adolescent HIV clinic. Longitudinal data were 
      analyzed using inverse propensity treatment-weighted linear growth models; 
      medians, interquartile ranges (IQR), means, and 95% confidence intervals are 
      provided. RESULTS: MACARTI screened 435 participants and identified 49 (11.3%) 
      HIV infections. The SOC arm enrolled 49 new HIV-infected individuals. The 98 
      participants, (49 in each arm) were: 85% men; 91% Black; mean age = 21 years 
      (SD : 1.8). Overall, 63% were linked within 3 months of diagnosis; linkage was 
      higher for MACARTI compared to SOC (96 vs. 57%, P < 0.001). Median linkage time 
      for MACARTI participants compared to SOC was 0.39 (IQR : 0.20-0.72) vs. 1.77 
      (IQR : 1.12-12.65) months (P < 0.001). MACARTI appointment adherence was higher 
      than SOC (86.1 vs. 77.2%, P = 0.018). In weight-adjusted models, mean CD4 T-cell 
      counts increased and mean HIV-1 RNA levels decreased in both arms over 12 months, 
      but the differences were more pronounced in the MACARTI arm. CONCLUSION: MACARTI 
      successfully identified and linked HIV-infected youth in Atlanta, USA. MACARTI 
      may serve as an effective linkage and care model for clinics serving HIV-infected 
      youth.
FAU - Camacho-Gonzalez, Andres F
AU  - Camacho-Gonzalez AF
AD  - aDivision of Pediatric Infectious Diseases, Department of Pediatrics, Emory 
      University School of Medicine bPonce Family and Youth Clinic, Grady Infectious 
      Diseases Program, Grady Health Systems cDepartment of Pediatrics, Emory 
      University School of Medicine dChildren's Healthcare of Atlanta eAtlanta Veterans 
      Affair Medical Center fHubert Department of Global Health, Rollins School of 
      Public Health, Emory University gDivision of HIV/AIDS Prevention, Centers for 
      Disease Control and Prevention hICF iDepartment of Biostatistics and 
      Bioinformatics, Rollins School of Public Health, Emory University jDepartment of 
      Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, 
      Georgia, USA.
FAU - Gillespie, Scott E
AU  - Gillespie SE
FAU - Thomas-Seaton, LaTeshia
AU  - Thomas-Seaton L
FAU - Frieson, Krystal
AU  - Frieson K
FAU - Hussen, Sophia A
AU  - Hussen SA
FAU - Murray, Ashley
AU  - Murray A
FAU - Gaul, Zaneta
AU  - Gaul Z
FAU - Leong, Traci
AU  - Leong T
FAU - Graves, Chanda
AU  - Graves C
FAU - Sutton, Madeline Y
AU  - Sutton MY
FAU - Chakraborty, Rana
AU  - Chakraborty R
LA  - eng
GR  - P30 AI050409/AI/NIAID NIH HHS/United States
GR  - U01 PS003322/PS/NCHHSTP CDC HHS/United States
GR  - UL1 TR000454/TR/NCATS NIH HHS/United States
PT  - Journal Article
PL  - England
TA  - AIDS
JT  - AIDS (London, England)
JID - 8710219
SB  - IM
MH  - Adolescent
MH  - Continuity of Patient Care
MH  - Diagnostic Services/*organization & administration/*statistics & numerical data
MH  - Diagnostic Tests, Routine/*methods/*statistics & numerical data
MH  - Early Diagnosis
MH  - Female
MH  - Georgia
MH  - HIV Infections/*diagnosis
MH  - Humans
MH  - Male
MH  - Pilot Projects
MH  - Prospective Studies
MH  - Young Adult
PMC - PMC5497786
MID - NIHMS875091
EDAT- 2017/07/01 06:00
MHDA- 2018/03/06 06:00
PMCR- 2017/07/05
CRDT- 2017/07/01 06:00
PHST- 2017/07/01 06:00 [entrez]
PHST- 2017/07/01 06:00 [pubmed]
PHST- 2018/03/06 06:00 [medline]
PHST- 2017/07/05 00:00 [pmc-release]
AID - 00002030-201707013-00010 [pii]
AID - AIDS-D-17-00100 [pii]
AID - 10.1097/QAD.0000000000001512 [doi]
PST - ppublish
SO  - AIDS. 2017 Jul 1;31 Suppl 3(Suppl 3):S267-S275. doi: 
      10.1097/QAD.0000000000001512.