PMID- 28666233
OWN - NLM
STAT- MEDLINE
DCOM- 20171226
LR  - 20200930
IS  - 1873-2690 (Electronic)
IS  - 0981-9428 (Linking)
VI  - 118
DP  - 2017 Sep
TI  - 5-Aminolevulinic acid improves DNA damage and DNA Methylation changes in 
      deltamethrin-exposed Phaseolus vulgaris seedlings.
PG  - 267-273
LID - S0981-9428(17)30217-6 [pii]
LID - 10.1016/j.plaphy.2017.06.026 [doi]
AB  - Deltamethrin, synthetic type II pyrethroid, is one of the most widely used 
      pesticide in agriculture. Intense use of deltamethrin can cause permanant or 
      temporary damages in nontarget plant species. In this study, we aimed to 
      determine DNA methylation change and DNA damage level in Phaseolus vulgaris 
      seedlings subjected to different concentrations of deltamethrin (0.02, 0.1 and 
      0.5 ppm). Coupled Restriction Enzyme Digestion-Random Amplification (CRED-RA) was 
      performed to analyze the changes of DNA methylation as well as Randomly Amplified 
      Polymorphic DNA (RAPD) was used for genotoxic influences estimation and genomic 
      stability. The results showed that deltamethrin caused to increase in RAPD 
      profile changes (DNA damage) and reduce in Genomic Template Stability (GTS). GTS 
      declined markedly in relation to increasing concentration of deltamethrin 
      applied. The lowest GTS value (71.4%) observed in 0.5 ppm deltamethrin treatment. 
      Also, DNA hypermethylation was occurred in all treatments. Moreover, alleviative 
      effect of 5-aminolevulinic acid (ALA) (20, 40 and 80 mg/l), one of the plant 
      growth regulators, was tested against the 0.5 ppm deltamethrin. Adverse effects 
      of deltamethrin on GTS decreased after ALA treatments, especially 20 mg/l 
      concentration. As a result, we concluded that ALA has a strong anti-genotoxic 
      agent against deltamethrin and it could be an alternative chemical to reduce 
      genetic damage in plants under deltamethrin stress conditions.
CI  - Copyright (c) 2017 Elsevier Masson SAS. All rights reserved.
FAU - Taspinar, Mahmut Sinan
AU  - Taspinar MS
AD  - Department of Agricultural Biotechnology, Faculty of Agriculture, Ataturk 
      University, Erzurum 25240, Turkey.
FAU - Aydin, Murat
AU  - Aydin M
AD  - Department of Field Crops, Faculty of Agriculture, Ataturk University, 25240 
      Erzurum, Turkey.
FAU - Arslan, Esra
AU  - Arslan E
AD  - Department of Biology, Faculty of Science, Ataturk University, Erzurum 25240, 
      Turkey. Electronic address: esra.arslan@atauni.edu.tr.
FAU - Yaprak, Muhammet
AU  - Yaprak M
AD  - Central Research and Application Laboratories, Agri Ibrahim Cecen University, 
      Agri 04100, Turkey.
FAU - Agar, Guleray
AU  - Agar G
AD  - Department of Biology, Faculty of Science, Ataturk University, Erzurum 25240, 
      Turkey.
LA  - eng
PT  - Journal Article
DEP - 20170621
PL  - France
TA  - Plant Physiol Biochem
JT  - Plant physiology and biochemistry : PPB
JID - 9882449
RN  - 0 (DNA, Plant)
RN  - 0 (Nitriles)
RN  - 0 (Pyrethrins)
RN  - 2JTS8R821G (decamethrin)
RN  - 88755TAZ87 (Aminolevulinic Acid)
SB  - IM
MH  - Aminolevulinic Acid/*pharmacokinetics
MH  - *DNA Damage
MH  - DNA Methylation/*drug effects
MH  - DNA, Plant/*metabolism
MH  - Fabaceae/*metabolism
MH  - Nitriles/*pharmacology
MH  - Pyrethrins/*pharmacology
MH  - Seedlings/*metabolism
OTO - NOTNLM
OT  - 5-Aminolevulinic acid
OT  - DNA methylation
OT  - Deltamethrin
OT  - Genomic instability
EDAT- 2017/07/01 06:00
MHDA- 2017/12/27 06:00
CRDT- 2017/07/01 06:00
PHST- 2017/03/17 00:00 [received]
PHST- 2017/06/20 00:00 [revised]
PHST- 2017/06/20 00:00 [accepted]
PHST- 2017/07/01 06:00 [pubmed]
PHST- 2017/12/27 06:00 [medline]
PHST- 2017/07/01 06:00 [entrez]
AID - S0981-9428(17)30217-6 [pii]
AID - 10.1016/j.plaphy.2017.06.026 [doi]
PST - ppublish
SO  - Plant Physiol Biochem. 2017 Sep;118:267-273. doi: 10.1016/j.plaphy.2017.06.026. 
      Epub 2017 Jun 21.