PMID- 28677054
OWN - NLM
STAT- MEDLINE
DCOM- 20180620
LR  - 20200330
IS  - 1432-1084 (Electronic)
IS  - 0938-7994 (Linking)
VI  - 28
IP  - 1
DP  - 2018 Jan
TI  - Left ventricular regional myocardial motion and twist function in repaired 
      tetralogy of Fallot evaluated by magnetic resonance tissue phase mapping.
PG  - 104-114
LID - 10.1007/s00330-017-4908-7 [doi]
AB  - OBJECTIVES: We aimed to characterise regional myocardial motion and twist 
      function in the left ventricles (LV) in patients with repaired tetralogy of 
      Fallot (rTOF) and preserved LV global function. METHODS: We recruited 47 rTOF 
      patients and 38 age-matched normal volunteers. Tissue phase mapping (TPM) was 
      performed for evaluating the LV myocardial velocity in longitudinal, radial, and 
      circumferential (Vz, Vr, and VO) directions in basal, middle, and apical slices. 
      The VO peak-to-peak (PTP) during systolic phases, the rotation angle of each 
      slice, and VO inconsistency were computed for evaluating LV twist function and VO 
      dyssynchrony. RESULTS: As compared to the controls, the rTOF patients presented 
      decreased RV ejection fraction (RVEF) (p = 0.002) and preserved global LV 
      ejection fraction (LVEF). They also demonstrated decreased systolic and diastolic 
      Vz in several LV segments and higher diastolic Vr in the septum (all p < 0.05). A 
      lower VO PTP, higher VO inconsistency, and reduced peak net rotation angle (all 
      p < 0.05) were observed. The aforementioned indices demonstrated an altered LV 
      twist function in rTOF patients in an early disease stage. CONCLUSIONS: MR TPM 
      could provide information about early abnormalities of LV regional motion and 
      twist function in rTOF patients with preserved LV global function. KEY POINTS: * 
      Patients with rTOF presented significantly reduced systolic and diastolic Vz in 
      the LV. * rTOF patients demonstrated significantly increased diastolic Vr in the 
      septum. * Abnormal characteristics of the segmental dynamic velocity evolution 
      were shown in rTOF. * rTOF patients presented altered circumferential rotation 
      and velocity inconsistency in early stage.
FAU - Chang, Meng-Chu
AU  - Chang MC
AD  - Department of Biomedical Engineering and Environmental Sciences, National Tsing 
      Hua University, No.101, Sec. 2, Kuang-Fu Rd., BMES Building, R415, Hsinchu, 300, 
      Taiwan.
FAU - Wu, Ming-Ting
AU  - Wu MT
AD  - Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
AD  - Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan.
FAU - Weng, Ken-Pen
AU  - Weng KP
AD  - Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan.
AD  - Department of Pediatrics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
AD  - Department of Physical Therapy, Shu-Zen Junior College of Medicine and 
      Management, Kaohsiung, Taiwan.
FAU - Su, Mao-Yuan
AU  - Su MY
AD  - Department of Medical Imaging, National Taiwan University Hospital, Taipei, 
      Taiwan.
FAU - Menza, Marius
AU  - Menza M
AD  - Department of Radiology, Medical Physics, Medical Center University of Freiburg, 
      Faculty of Medicine, University of Freiburg, Freiburg, Germany.
FAU - Huang, Hung-Chieh
AU  - Huang HC
AD  - Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
FAU - Peng, Hsu-Hsia
AU  - Peng HH
AUID- ORCID: 0000-0002-6318-1377
AD  - Department of Biomedical Engineering and Environmental Sciences, National Tsing 
      Hua University, No.101, Sec. 2, Kuang-Fu Rd., BMES Building, R415, Hsinchu, 300, 
      Taiwan. hhpeng@mx.nthu.edu.tw.
LA  - eng
GR  - VGHUST104-G7-7-2/Veterans General Hospitals and University System of Taiwan Joint 
      Research Program/
GR  - VGHUST104-G7-7-3/Veterans General Hospitals and University System of Taiwan Joint 
      Research Program/
GR  - NSC 102-2320-B-007-003-MY3/Ministry of Science and Technology in Taiwan/
PT  - Journal Article
DEP - 20170704
PL  - Germany
TA  - Eur Radiol
JT  - European radiology
JID - 9114774
SB  - IM
MH  - Adult
MH  - Diastole
MH  - Female
MH  - Heart Ventricles/diagnostic imaging/physiopathology
MH  - Humans
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - Motion
MH  - Postoperative Complications/*diagnostic imaging/*physiopathology
MH  - Prospective Studies
MH  - Tetralogy of Fallot/physiopathology/*surgery
MH  - Ventricular Dysfunction, Left/*diagnostic imaging/*physiopathology
MH  - Young Adult
OTO - NOTNLM
OT  - Myocardial motion
OT  - Tetralogy of Fallot
OT  - Tissue phase mapping
OT  - Twist
OT  - Ventricular function
EDAT- 2017/07/06 06:00
MHDA- 2018/06/21 06:00
CRDT- 2017/07/06 06:00
PHST- 2017/01/26 00:00 [received]
PHST- 2017/05/23 00:00 [accepted]
PHST- 2017/03/20 00:00 [revised]
PHST- 2017/07/06 06:00 [pubmed]
PHST- 2018/06/21 06:00 [medline]
PHST- 2017/07/06 06:00 [entrez]
AID - 10.1007/s00330-017-4908-7 [pii]
AID - 10.1007/s00330-017-4908-7 [doi]
PST - ppublish
SO  - Eur Radiol. 2018 Jan;28(1):104-114. doi: 10.1007/s00330-017-4908-7. Epub 2017 Jul 
      4.