PMID- 28684001
OWN - NLM
STAT- MEDLINE
DCOM- 20170911
LR  - 20170911
IS  - 1532-9488 (Electronic)
IS  - 1043-0679 (Linking)
VI  - 29
IP  - 1
DP  - 2017 Spring
TI  - Five-year Experience With Arterial Switch Operation in the First Hours of Life.
PG  - 70-76
LID - S1043-0679(17)30022-9 [pii]
LID - 10.1053/j.semtcvs.2017.01.011 [doi]
AB  - We assessed morbidity after 2 management strategies for arterial switch operation 
      (ASO) in a single institution: first hours of life surgery and conventional 
      approach. From September 2009 to September 2014, 346 consecutive patients who 
      underwent ASO were enrolled. The study group included 92 patients who underwent 
      ASO in the first 24 hours after birth (group I). The control group consisted of 
      254 patients who underwent ASO after 24 hours of life in the conventional way 
      (group II). Three outcomes were analyzed: postoperative ventilation time (VT), 
      post-extubation hospital length of stay (peLOS), and a composite morbidity index, 
      defined as postoperative VT + peLOS + occurrence of selected major complications. 
      Overall 30-day survival was 98% (2 [2%] group I vs 5 [2%] group II, P = 1.000). 
      Fifty (13.3%) major complications were observed: 14 (15%) in group I and 36 (15%) 
      in group II (P = 0.635). Although peLOS and morbidity index did not differ 
      significantly between groups, postoperative VT (42 hours [24, 67] vs 27 hours 
      [22, 47], P = 0.008) and total hospital stay were significantly longer in group 
      II (18 days [10, 19] vs 14 days [12, 18]). A median volume of 80 mL (60-100 mL) 
      of autologous umbilical cord blood was collected (80 mL, group 1 vs 60 mL, group 
      II; P = 0.090). Homologous blood cell transfusion was avoided in 70 patients 
      (78%) in group I and in 13 patients (6%) in group II (P < 0.001). Arterial switch 
      operation during the initial 24 hours of life has similar outcomes in view of 
      morbidity and mortality to the conventional approach.
CI  - Copyright (c) 2017 Elsevier Inc. All rights reserved.
FAU - Chasovskyi, Kyrylo
AU  - Chasovskyi K
AD  - Department of Intensive care and Perfusiology, Ukrainian Children's Cardiac 
      Center, Kyiv, Ukraine. Electronic address: kchasovskiy82@gmail.com.
FAU - Mykychak, Yaroslav
AU  - Mykychak Y
AD  - Department of Cardiac Surgery, Ukrainian Children's Cardiac Center, Kyiv, 
      Ukraine.
FAU - Rudenko, Nadiia
AU  - Rudenko N
AD  - Department of Cardiology, Ukrainian Children's Cardiac Center, Kyiv, Ukraine.
FAU - Vorobyova, Hanna
AU  - Vorobyova H
AD  - Department of Cardiology, Ukrainian Children's Cardiac Center, Kyiv, Ukraine.
FAU - Yemets, Illya
AU  - Yemets I
AD  - Department of Cardiac Surgery, Ukrainian Children's Cardiac Center, Kyiv, 
      Ukraine.
LA  - eng
PT  - Journal Article
DEP - 20170224
PL  - United States
TA  - Semin Thorac Cardiovasc Surg
JT  - Seminars in thoracic and cardiovascular surgery
JID - 8917640
SB  - IM
CIN - Semin Thorac Cardiovasc Surg. 2017 Spring;29(1):77-78. PMID: 28684002
MH  - Age Factors
MH  - *Arterial Switch Operation/adverse effects/methods/mortality
MH  - Hospital Mortality
MH  - Humans
MH  - Infant, Newborn
MH  - Length of Stay
MH  - Postoperative Complications/etiology
MH  - Recovery of Function
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Time Factors
MH  - Transposition of Great Vessels/diagnostic 
      imaging/mortality/physiopathology/*surgery
MH  - Treatment Outcome
OTO - NOTNLM
OT  - CHD
OT  - arterial switch operation
OT  - blood
OT  - cardiopulmonary bypass
OT  - neonates
EDAT- 2017/07/08 06:00
MHDA- 2017/09/12 06:00
CRDT- 2017/07/08 06:00
PHST- 2017/01/12 00:00 [accepted]
PHST- 2017/07/08 06:00 [entrez]
PHST- 2017/07/08 06:00 [pubmed]
PHST- 2017/09/12 06:00 [medline]
AID - S1043-0679(17)30022-9 [pii]
AID - 10.1053/j.semtcvs.2017.01.011 [doi]
PST - ppublish
SO  - Semin Thorac Cardiovasc Surg. 2017 Spring;29(1):70-76. doi: 
      10.1053/j.semtcvs.2017.01.011. Epub 2017 Feb 24.