PMID- 28685623
OWN - NLM
STAT- MEDLINE
DCOM- 20171106
LR  - 20211110
IS  - 1744-7666 (Electronic)
IS  - 1465-6566 (Linking)
VI  - 18
IP  - 12
DP  - 2017 Aug
TI  - Cardiovascular disease prevention strategies for type 2 diabetes mellitus.
PG  - 1243-1260
LID - 10.1080/14656566.2017.1351946 [doi]
AB  - Type 2 diabetes mellitus (T2DM) is associated with several cardiovascular (CV) 
      risk factors such as insulin resistance, obesity, hypertension, dyslipidaemia, 
      non-alcoholic fatty liver disease as well as platelet and haemostatic 
      abnormalities increasing the risk of thrombosis. Therefore, T2DM patients are at 
      an increased risk for CV disease (CVD). Areas covered: This narrative review 
      discusses the treatment of T2DM. This includes lifestyle measures (diet, exercise 
      and smoking cessation) as well as hypolipidaemic, antihypertensive, weight 
      reducing, antiplatelet and glucose lowering drugs. The focus is on the effects of 
      these therapeutic strategies on CVD risk. Randomized controlled clinical trials 
      (RCTs) reporting CVD outcomes with such drugs in T2DM patients are also reviewed. 
      Expert opinion: Apart from current guidelines, the findings of RCTs on CVD 
      outcomes in T2DM patients should be taken into consideration in daily clinical 
      practice. Multiple risk factors should be targeted simultaneously in such 
      high-risk patients in order to efficiently reduce the risk of CV events.
FAU - Katsiki, Niki
AU  - Katsiki N
AD  - a Second Department of Propaedeutic Internal Medicine , Medical School, Aristotle 
      University of Thessaloniki, Hippocration Hospital , Thessaloniki , Greece.
FAU - Purrello, Francesco
AU  - Purrello F
AD  - b Department of Clinical and Experimental Medicine , University of Catania , 
      Catania , Italy.
FAU - Tsioufis, Costas
AU  - Tsioufis C
AD  - c First Cardiology Clinic , National and Kapodistrian University of Athens, 
      Hippokration Hospital , Athens , Greece.
FAU - Mikhailidis, Dimitri P
AU  - Mikhailidis DP
AD  - d Department of Clinical Biochemistry , Royal Free Hospital Campus, University 
      College London Medical School, University College London (UCL) , London , UK.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20170714
PL  - England
TA  - Expert Opin Pharmacother
JT  - Expert opinion on pharmacotherapy
JID - 100897346
SB  - IM
MH  - Cardiovascular Diseases/*prevention & control
MH  - Diabetes Mellitus, Type 2/complications/*drug therapy
MH  - Humans
MH  - Insulin Resistance
MH  - Life Style
MH  - Practice Guidelines as Topic
MH  - Randomized Controlled Trials as Topic
MH  - Risk Factors
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Type 2 diabetes mellitus
OT  - antidiabetic drugs
OT  - antihypertensive
OT  - antiplatelet drugs
OT  - cardiovascular risk
OT  - hypolipidaemic drugs
EDAT- 2017/07/08 06:00
MHDA- 2017/11/07 06:00
CRDT- 2017/07/08 06:00
PHST- 2017/07/08 06:00 [pubmed]
PHST- 2017/11/07 06:00 [medline]
PHST- 2017/07/08 06:00 [entrez]
AID - 10.1080/14656566.2017.1351946 [doi]
PST - ppublish
SO  - Expert Opin Pharmacother. 2017 Aug;18(12):1243-1260. doi: 
      10.1080/14656566.2017.1351946. Epub 2017 Jul 14.