PMID- 28688211 OWN - NLM STAT- MEDLINE DCOM- 20171204 LR - 20180526 IS - 1531-4995 (Electronic) IS - 0023-852X (Linking) VI - 127 IP - 12 DP - 2017 Dec TI - Reducing sedation time for thyroplasty with arytenoid adduction with sequential anesthetic technique. PG - 2813-2817 LID - 10.1002/lary.26743 [doi] AB - OBJECTIVE: To determine the extent to which a sequential anesthetic technique 1) shortens time under sedation for thyroplasty with arytenoid adduction (TP-AA), 2) affects the total operative time, and 3) changes the voice outcome compared to TP-AA performed entirely under sedation/analgesia. STUDY DESIGN: Case-control study. METHODS: A new sequential anesthetic technique of performing most of the TP-AA surgery under general anesthesia (GA), followed by transition to sedation/analgesia (SA) for voice assessment, was developed to achieve smooth emergence from GA. Twenty-five TP-AA cases performed with the sequential GA-SA technique were compared with 25 TP-AA controls performed completely under sedation/analgesia. The primary outcome measure was the time under sedation. Voice improvement, as assessed by Consensus Auditory-Perceptual Evaluation of Voice, and total operative time were secondary outcome measures. RESULTS: With the conventional all-SA anesthetic, the duration of SA was 209 +/- 26.3 minutes. With the sequential GA-SA technique, the duration of SA was 79.0 +/- 18.9 minutes, a 62.3% reduction (P < 0.0001). There was no significant difference in the total operative time (209.5 vs. 200.9 minutes; P = 0.42) or in voice outcome. This sequential anesthetic technique has been easily adopted by multiple anesthesiologists and nurse anesthetists at our institution. CONCLUSION: TP-AA is effectively performed under sequential GA-SA technique with a significant reduction in the duration of time under sedation. This allows the surgeon to perform the technically more challenging part of the surgery under GA, without having to contend with variability in patient tolerance for laryngeal manipulation under sedation. LEVEL OF EVIDENCE: 3b. Laryngoscope, 127:2813-2817, 2017. CI - (c) 2017 The American Laryngological, Rhinological and Otological Society, Inc. FAU - Saadeh, Charles K AU - Saadeh CK AD - Clinical Center for Voice Care, Department of Otolaryngology-Head and Neck Surgery. FAU - Rosero, Eric B AU - Rosero EB AD - Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, Texas, U.S.A. FAU - Joshi, Girish P AU - Joshi GP AD - Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, Texas, U.S.A. FAU - Ozayar, Esra AU - Ozayar E AD - Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, Texas, U.S.A. FAU - Mau, Ted AU - Mau T AUID- ORCID: 0000-0002-1804-6707 AD - Clinical Center for Voice Care, Department of Otolaryngology-Head and Neck Surgery. LA - eng PT - Journal Article DEP - 20170708 PL - United States TA - Laryngoscope JT - The Laryngoscope JID - 8607378 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Anesthesia, General/*methods MH - Arytenoid Cartilage/*surgery MH - Case-Control Studies MH - Conscious Sedation/*methods MH - Female MH - Humans MH - Laryngoplasty/*methods MH - Male MH - Middle Aged MH - Time Factors MH - Young Adult OTO - NOTNLM OT - Vocal fold paralysis OT - arytenoid adduction OT - laryngeal framework surgery OT - medialization laryngoplasty OT - moderate sedation OT - sedation/analgesia OT - thyroplasty EDAT- 2017/07/09 06:00 MHDA- 2017/12/05 06:00 CRDT- 2017/07/09 06:00 PHST- 2017/03/26 00:00 [received] PHST- 2017/05/22 00:00 [accepted] PHST- 2017/07/09 06:00 [pubmed] PHST- 2017/12/05 06:00 [medline] PHST- 2017/07/09 06:00 [entrez] AID - 10.1002/lary.26743 [doi] PST - ppublish SO - Laryngoscope. 2017 Dec;127(12):2813-2817. doi: 10.1002/lary.26743. Epub 2017 Jul 8.