PMID- 28691048
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220310
IS  - 2364-3722 (Print)
IS  - 2196-9736 (Electronic)
IS  - 2196-9736 (Linking)
VI  - 5
IP  - 7
DP  - 2017 Jul
TI  - Feasibility of transnasal endoscopy in screening for esophageal and gastric 
      varices in patients with chronic liver disease.
PG  - E646-E651
LID - 10.1055/s-0043-107781 [doi]
AB  - BACKGROUND AND STUDY AIMS:  Screening for esophageal and gastric varices is 
      indicated for patients with portal hypertension or cirrhosis. Typically, 
      conventional endoscopy is used; however, the need for sedation increases the 
      costs and risks, especially in cirrhotic patients. Use of transnasal endoscopy 
      with an ultrathin endoscope enables study of the upper gastrointestinal tract 
      without the need for sedation. The objective of this study is to evaluate the 
      feasibility of transnasal endoscopy in screening for esophageal and gastric 
      varices in patients with chronic liver disease. PATIENTS AND METHODS: This was a 
      prospective study in which transnasal endoscopy was carried out in patients with 
      cirrhosis or portal hypertension who had indications for screening of esophageal 
      and gastric varices. The following variables were evaluated: demographical data, 
      duration of procedure, patient tolerance and acceptance, adverse events (AEs), 
      endoscopic findings and interobserver agreement related to portal hypertension 
      alterations ( kappa index). RESULTS: A total of 50 patients entered the study. 
      The most common cause of liver disease was chronic viral hepatitis (66 %). Among 
      the cirrhotic patients, most of the patients were Child-Pugh A (74 %). In 5 
      patients (10 %), nasal intubation was not possible. Two patients (4 %) 
      experienced minor epistaxis. Tolerance was excellent or good in 92 % according 
      with a visual analogic scale. In 16 patients (32 %), esophageal varices were 
      detected and in 2 patients (4 %) gastric varices were detected. The mean duration 
      of the procedure was 7 minutes. CONCLUSIONS: Transnasal endoscopy is feasible, 
      effective and well tolerated for screening of esophageal and gastric varices in 
      patients with chronic liver disease. It can be performed in outpatient clinics 
      safely and without the use of sedation.
FAU - de Faria, Anderson Antonio
AU  - de Faria AA
AD  - Hospital das Clinicas, Federal University of Mimas Gerais, Alfa Institute of 
      Gastroenterology, Belo Horizonte, Minas Gerais, Brazil.
FAU - Dias, Carlos Alberto Freitas
AU  - Dias CAF
AD  - Hospital das Clinicas, Federal University of Mimas Gerais, Alfa Institute of 
      Gastroenterology, Belo Horizonte, Minas Gerais, Brazil.
FAU - Dias Moetzsohn, Luciana
AU  - Dias Moetzsohn L
AD  - Hospital das Clinicas, Federal University of Mimas Gerais, Alfa Institute of 
      Gastroenterology, Belo Horizonte, Minas Gerais, Brazil.
FAU - de Castro Carvalho, Silas
AU  - de Castro Carvalho S
AD  - Hospital das Clinicas, Federal University of Mimas Gerais, Alfa Institute of 
      Gastroenterology, Belo Horizonte, Minas Gerais, Brazil.
FAU - Ferrari, Tereza Abreu
AU  - Ferrari TA
AD  - Hospital das Clinicas, Federal University of Mimas Gerais, Alfa Institute of 
      Gastroenterology, Belo Horizonte, Minas Gerais, Brazil.
FAU - Nunes Arantes, Vitor
AU  - Nunes Arantes V
AD  - Hospital das Clinicas, Federal University of Mimas Gerais, Alfa Institute of 
      Gastroenterology, Belo Horizonte, Minas Gerais, Brazil.
LA  - eng
PT  - Journal Article
DEP - 20170706
PL  - Germany
TA  - Endosc Int Open
JT  - Endoscopy international open
JID - 101639919
PMC - PMC5500113
COIS- Competing interests None
EDAT- 2017/07/12 06:00
MHDA- 2017/07/12 06:01
PMCR- 2017/07/01
CRDT- 2017/07/11 06:00
PHST- 2016/10/23 00:00 [received]
PHST- 2017/03/24 00:00 [accepted]
PHST- 2017/07/11 06:00 [entrez]
PHST- 2017/07/12 06:00 [pubmed]
PHST- 2017/07/12 06:01 [medline]
PHST- 2017/07/01 00:00 [pmc-release]
AID - 10.1055/s-0043-107781 [doi]
PST - ppublish
SO  - Endosc Int Open. 2017 Jul;5(7):E646-E651. doi: 10.1055/s-0043-107781. Epub 2017 
      Jul 6.