PMID- 28693891
OWN - NLM
STAT- MEDLINE
DCOM- 20180604
LR  - 20180604
IS  - 1874-1754 (Electronic)
IS  - 0167-5273 (Linking)
VI  - 248
DP  - 2017 Dec 1
TI  - An alarming trend: Change in the risk profile of patients with ST elevation 
      myocardial infarction over the last two decades.
PG  - 69-72
LID - S0167-5273(16)34144-4 [pii]
LID - 10.1016/j.ijcard.2017.05.011 [doi]
AB  - BACKGROUND: Coronary artery disease (CAD) is the leading cause of mortality 
      around the world. We sought to study changes in the risk profile of patients 
      presenting with ST elevation myocardial infarction (STEMI). METHODS: We 
      retrospectively studied all patients presenting with STEMI to our center between 
      1995 and 2014. Patients were divided into four quartiles, 5years each. Baseline 
      risk factors and comorbidities were recorded. Sub-analysis was done for patients 
      with established CAD and their household incomes. RESULTS: A total of 3913 
      patients (67.9% males) were included; 42.5% presented with anterior STEMI and 
      57.5% inferior STEMI. Ages were 64+/-12, 62+/-13, 61+/-13 and 60+/-13 in the four 
      quartiles respectively. Obesity prevalence was 31, 37, 38 and 40% and diabetes 
      mellitus prevalence was 24, 25, 24 and 31%, while hypertension was 55, 67, 70 and 
      77%, respectively, p<0.01 for all. Smoking prevalence was 28, 32, 42 and 46, 
      p<0.01. When subgroup analysis was done for patients with history of CAD, 
      prevalence of smoking, obesity, diabetes and hypertension significantly increased 
      across the four quartiles. When patients were divided to four groups based on 
      household income (poor, low middle, middle and high income), prevalence of 
      diabetes, hypertension, smoking and obesity were significantly higher in patients 
      with low income. CONCLUSION: Despite better understanding of cardiovascular risk 
      factors and more focus on preventive cardiology, patients presenting with STEMI 
      over the past 20years are getting younger and more obese, with more prevalence of 
      smoking, hypertension, and diabetes mellitus. This trend is greater in the lower 
      income population.
CI  - Copyright (c) 2017 Elsevier B.V. All rights reserved.
FAU - Mentias, Amgad
AU  - Mentias A
AD  - Heart and Vascular Institute, Cleveland Clinic, OH, United States.
FAU - Hill, Elizabeth
AU  - Hill E
AD  - Heart and Vascular Institute, Cleveland Clinic, OH, United States.
FAU - Barakat, Amr F
AU  - Barakat AF
AD  - Heart and Vascular Institute, Cleveland Clinic, OH, United States.
FAU - Raza, Mohammad Q
AU  - Raza MQ
AD  - Heart and Vascular Institute, Cleveland Clinic, OH, United States.
FAU - Youssef, Dalia
AU  - Youssef D
AD  - Heart and Vascular Institute, Cleveland Clinic, OH, United States.
FAU - Banerjee, Kinjal
AU  - Banerjee K
AD  - Heart and Vascular Institute, Cleveland Clinic, OH, United States.
FAU - Sawant, Abhishek C
AU  - Sawant AC
AD  - Heart and Vascular Institute, Cleveland Clinic, OH, United States.
FAU - Ellis, Stephen
AU  - Ellis S
AD  - Heart and Vascular Institute, Cleveland Clinic, OH, United States.
FAU - Murat Tuzcu, E
AU  - Murat Tuzcu E
AD  - Heart and Vascular Institute, Cleveland Clinic, OH, United States.
FAU - Kapadia, Samir R
AU  - Kapadia SR
AD  - Heart and Vascular Institute, Cleveland Clinic, OH, United States. Electronic 
      address: kapadis@ccf.org.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20170708
PL  - Netherlands
TA  - Int J Cardiol
JT  - International journal of cardiology
JID - 8200291
SB  - IM
MH  - Aged
MH  - Diabetes Mellitus/diagnosis/*epidemiology/physiopathology
MH  - Female
MH  - Humans
MH  - Hypertension/diagnosis/*epidemiology/physiopathology
MH  - Male
MH  - Middle Aged
MH  - Obesity/diagnosis/*epidemiology/physiopathology
MH  - Prospective Studies
MH  - Retrospective Studies
MH  - Risk Factors
MH  - ST Elevation Myocardial Infarction/diagnosis/*epidemiology/physiopathology
MH  - Smoking/*epidemiology/trends
OTO - NOTNLM
OT  - Ischemic heart disease
OT  - Risk factors
OT  - Risk profile
OT  - ST-elevation myocardial infarction
EDAT- 2017/07/12 06:00
MHDA- 2018/06/05 06:00
CRDT- 2017/07/12 06:00
PHST- 2016/11/26 00:00 [received]
PHST- 2017/04/24 00:00 [revised]
PHST- 2017/05/04 00:00 [accepted]
PHST- 2017/07/12 06:00 [pubmed]
PHST- 2018/06/05 06:00 [medline]
PHST- 2017/07/12 06:00 [entrez]
AID - S0167-5273(16)34144-4 [pii]
AID - 10.1016/j.ijcard.2017.05.011 [doi]
PST - ppublish
SO  - Int J Cardiol. 2017 Dec 1;248:69-72. doi: 10.1016/j.ijcard.2017.05.011. Epub 2017 
      Jul 8.