PMID- 28700039 OWN - NLM STAT- MEDLINE DCOM- 20180228 LR - 20220317 IS - 2238-0019 (Electronic) IS - 2237-6089 (Linking) VI - 39 IP - 2 DP - 2017 Apr-Jun TI - Sexual dysfunction in females with depression: a cross-sectional study. PG - 106-109 LID - S2237-60892017000200106 [pii] LID - 10.1590/2237-6089-2016-0072 [doi] AB - INTRODUCTION: Female sexual dysfunction (FSD) in depression albeit common is strikingly understudied. The condition, if addressed properly, can be readily cured, improving the quality of life of the patient. METHODS: A consecutive sample of drug-naive married female patients with depression was assessed. Depression was diagnosed using the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I). Depression severity was assessed using the Hamilton Depression Rating Scale (HAM-D), and sexual dysfunction, the Female Sexual Function Index (FSFI). RESULTS: Sexual dysfunction was found in 90% of the patients in our study. Patients with medical comorbidities showed a significant decrease in the desire subset of the FSFI (Mann-Whitney U=11.0, p=0.009), however there was no significant association with other subsets. Patients who expressed passive death wishes had higher scores on all indicators of sexual function and a significantly higher score in the orgasm subset of the FSFI (Mann-Whitney U=11.0, p=0.009). CONCLUSION: The study showed a high prevalence of FSD in depressed females regardless of type and severity of depression. Depression with medical comorbidities was associated with a significant decrease in desire. Patients who expressed passive death wishes showed improved sexual function and significantly better orgasm. FAU - Sreelakshmy, Krishnankutty AU - Sreelakshmy K AD - Department of Obstetrics and Gynaecology, Sree Mookambika Institute of Medical Sciences, Padanilam, Kulasekharam, Tamil Nadu, India. FAU - Velayudhan, Rajmohan AU - Velayudhan R AD - Department of Psychiatry, MES Medical College, Perintalmanna, Malappuram, Kerala, India. FAU - Kuriakose, Deepak AU - Kuriakose D AD - Department of Psychiatry, MES Medical College, Perintalmanna, Malappuram, Kerala, India. FAU - Nair, Rema AU - Nair R AD - Department of Obstetrics and Gynaecology, Sree Mookambika Institute of Medical Sciences, Padanilam, Kulasekharam, Tamil Nadu, India. LA - eng PT - Journal Article PL - Brazil TA - Trends Psychiatry Psychother JT - Trends in psychiatry and psychotherapy JID - 101610695 SB - IM MH - Adult MH - Comorbidity MH - Cross-Sectional Studies MH - Depressive Disorder, Major/complications/*epidemiology/psychology MH - Female MH - Humans MH - Marriage MH - Middle Aged MH - Prevalence MH - Psychiatric Status Rating Scales MH - Severity of Illness Index MH - Sexual Dysfunction, Physiological/complications/*epidemiology MH - Sexual Dysfunctions, Psychological/complications/*epidemiology MH - Suicidal Ideation MH - Young Adult EDAT- 2017/07/13 06:00 MHDA- 2018/03/01 06:00 CRDT- 2017/07/13 06:00 PHST- 2016/10/12 00:00 [received] PHST- 2017/03/08 00:00 [accepted] PHST- 2017/07/13 06:00 [entrez] PHST- 2017/07/13 06:00 [pubmed] PHST- 2018/03/01 06:00 [medline] AID - S2237-60892017000200106 [pii] AID - 10.1590/2237-6089-2016-0072 [doi] PST - ppublish SO - Trends Psychiatry Psychother. 2017 Apr-Jun;39(2):106-109. doi: 10.1590/2237-6089-2016-0072.