PMID- 28708715 OWN - NLM STAT- MEDLINE DCOM- 20171003 LR - 20171003 IS - 1532-3145 (Electronic) IS - 0363-8715 (Linking) VI - 41 IP - 5 DP - 2017 Sep/Oct TI - Relationship of Nonseptal Late Gadolinium Enhancement to Ventricular Tachyarrhythmia in Hypertrophic Cardiomyopathy. PG - 768-771 LID - 10.1097/RCT.0000000000000599 [doi] AB - OBJECTIVE: This study aimed to determine the relationship between the extent and the location of late gadolinium enhancement (LGE) and ventricular tachyarrhythmia or implantable cardioverter defibrillator (ICD) in hypertrophic cardiomyopathy (HCM). METHODS: We enrolled 115 patients with HCM and LGE. The location of LGE was divided into septal and nonseptal segments. Clinical backgrounds and LGE were compared in patients between with and without the arrhythmia or consequent ICD installation. RESULTS: There were significant differences in the number of risk markers, left ventricular ejection fraction, extent of global LGE, and extent of nonseptal LGE between the groups (P < 0.01). Multivariate analysis revealed that the number of risk markers and extent of nonseptal LGE contributed to ventricular tachyarrhythmia or ICD installation (P < 0.01). CONCLUSIONS: The nonseptal LGE is related to ventricular tachyarrhythmia or ICD installation. We should be vigilant for nonseptal LGE when applying LGE to risk stratification for HCM. FAU - Amano, Yasuo AU - Amano Y AD - From the *Departments of Radiology, and daggerCardiology and Intensive Cardiac Care Unit, Nippon Medical School; and double daggerDepartment of Radiology, Nihon University Hospital, Tokyo, Japan. FAU - Yanagisawa, Fumi AU - Yanagisawa F FAU - Kitamura, Mitsunobu AU - Kitamura M FAU - Tachi, Masaki AU - Tachi M FAU - Kumita, Shinichiro AU - Kumita S LA - eng PT - Journal Article PL - United States TA - J Comput Assist Tomogr JT - Journal of computer assisted tomography JID - 7703942 RN - 0 (Contrast Media) RN - AU0V1LM3JT (Gadolinium) SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Cardiomyopathy, Hypertrophic/complications/*diagnostic imaging MH - Contrast Media/*pharmacokinetics MH - Female MH - Gadolinium/*pharmacokinetics MH - Heart Septum MH - Humans MH - Image Enhancement/*methods MH - Magnetic Resonance Imaging MH - Male MH - Middle Aged MH - Retrospective Studies MH - Tachycardia, Ventricular/complications/*diagnostic imaging MH - Young Adult EDAT- 2017/07/15 06:00 MHDA- 2017/10/04 06:00 CRDT- 2017/07/15 06:00 PHST- 2017/07/15 06:00 [pubmed] PHST- 2017/10/04 06:00 [medline] PHST- 2017/07/15 06:00 [entrez] AID - 10.1097/RCT.0000000000000599 [doi] PST - ppublish SO - J Comput Assist Tomogr. 2017 Sep/Oct;41(5):768-771. doi: 10.1097/RCT.0000000000000599.