PMID- 28718889
OWN - NLM
STAT- MEDLINE
DCOM- 20180723
LR  - 20220408
IS  - 1525-1594 (Electronic)
IS  - 0160-564X (Linking)
VI  - 41
IP  - 12
DP  - 2017 Dec
TI  - Veno-Arterial Extracorporeal Membrane Oxygenation Support in Patients Undergoing 
      Aortic Surgery.
PG  - 1113-1120
LID - 10.1111/aor.12951 [doi]
AB  - Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is an option for 
      mechanical support for patients with postcardiotomy cardiogenic shock (PCS). 
      However, the use of VA-ECMO in patients suffering from aortic disease with PCS 
      has not been greatly reported. This is a retrospective review of adult patients 
      undergoing aortic surgery who received VA-ECMO support to treat refractory PCS 
      from August 2009 to May 2016. A total of 36 patients who underwent aortic surgery 
      with VA-ECMO support for refractory PCS were included. Preoperative, 
      perioperative, and postoperative variables were assessed and analyzed for 
      possible correlation with in-hospital mortality. After a mean duration of 
      3.6 +/- 2.9 days, 24 patients (67%) were weaned off VA-ECMO, and 18 patients (50%) 
      were discharged from the hospital. The overall in-hospital mortality was 50%. The 
      main cause of death was multiple organ dysfunction. The survivors had a lower 
      level of preoperative creatine kinase-MB (CK-MB), a higher rate of antegrade 
      cannulation, and a lower lactate level at 12 h, respectively. Relevant factors 
      for in-hospital mortality were retrograde-flow cannulation (odds ratio [OR], 
      2.49), peak lactate levels greater than 20 mmol/L (OR, 5.0), and preoperative 
      CK-MB greater than 100 IU/L (OR, 6.40). Antegrade cannulation may provide better 
      perfusion and should be emphasized to improve outcomes. Additionally, levels of 
      peak serum lactate and preoperative CK-MB may be relevant factors for in-hospital 
      mortality in aortic patients with PCS.
CI  - (c) 2017 International Center for Artificial Organs and Transplantation and Wiley 
      Periodicals, Inc.
FAU - Zhong, Zhaopeng
AU  - Zhong Z
AD  - Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical 
      University, Beijing, China.
AD  - Beijing Institute of Heart Lung Blood Vessel Disease, Beijing, China.
FAU - Jiang, Chunjing
AU  - Jiang C
AD  - Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical 
      University, Beijing, China.
FAU - Yang, Feng
AU  - Yang F
AD  - Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical 
      University, Beijing, China.
FAU - Hao, Xing
AU  - Hao X
AD  - Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical 
      University, Beijing, China.
FAU - Xing, Jialin
AU  - Xing J
AD  - Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical 
      University, Beijing, China.
FAU - Wang, Hong
AU  - Wang H
AD  - Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical 
      University, Beijing, China.
FAU - Hou, Xiaotong
AU  - Hou X
AUID- ORCID: 0000-0002-7047-0492
AD  - Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical 
      University, Beijing, China.
AD  - Beijing Institute of Heart Lung Blood Vessel Disease, Beijing, China.
LA  - eng
PT  - Journal Article
DEP - 20170718
PL  - United States
TA  - Artif Organs
JT  - Artificial organs
JID - 7802778
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aortic Diseases/blood/*complications/mortality/*surgery
MH  - *Extracorporeal Membrane Oxygenation/methods
MH  - Female
MH  - Hospital Mortality
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Perioperative Period
MH  - Retrospective Studies
MH  - Shock, Cardiogenic/blood/*complications/mortality/*therapy
MH  - Treatment Outcome
OTO - NOTNLM
OT  - -Aortic surgery
OT  - -Postcardiotomy cardiogenic shock
OT  - Extracorporeal membrane oxygenation
EDAT- 2017/07/19 06:00
MHDA- 2018/07/24 06:00
CRDT- 2017/07/19 06:00
PHST- 2016/12/19 00:00 [received]
PHST- 2017/02/18 00:00 [revised]
PHST- 2017/03/14 00:00 [accepted]
PHST- 2017/07/19 06:00 [pubmed]
PHST- 2018/07/24 06:00 [medline]
PHST- 2017/07/19 06:00 [entrez]
AID - 10.1111/aor.12951 [doi]
PST - ppublish
SO  - Artif Organs. 2017 Dec;41(12):1113-1120. doi: 10.1111/aor.12951. Epub 2017 Jul 
      18.