PMID- 28723829 OWN - NLM STAT- MEDLINE DCOM- 20180611 LR - 20180611 IS - 1473-5830 (Electronic) IS - 0954-6928 (Linking) VI - 28 IP - 7 DP - 2017 Nov TI - Prognostic implication of early ventricular fibrillation among patients with ST elevation myocardial infarction. PG - 570-576 LID - 10.1097/MCA.0000000000000532 [doi] AB - OBJECTIVE: The aim of this study was to analyze the prognosis of patients presenting early ventricular fibrillation (VF) in the setting of ST elevation myocardial infarction (STEMI). PATIENTS AND METHODS: Among patients included in the ARIAM (Analisis del Retraso en el Infarto Agudo de Miocardio) registry with the diagnosis of STEMI, those who received primary revascularization and were admitted in the first 12 h were analyzed retrospectively. RESULTS: From January 2007 to January 2012, 8340 patients were included in the STEMI cohort and 680 (8.2%) of them presented with VF before admission to the ICU (VF). This group comprised younger patients with fewer comorbidities. They received more often primary angioplasty (33.7 vs. 24.9%; P<0.001), had more prevalence of Killip class greater than or equal to 2 at admission (37.5 vs. 17.8%; P<0.001), and suffered more often cardiogenic shock (18.5 vs. 5.9%, P<0.001). By logistic regression analysis, VF was associated with a greater in-hospital mortality [odds rate (OR): 2.08, 95% confidence interval (CI): 1.57-2.81, P<0.001]. After a propensity score matching process, VF was associated with in-hospital mortality (OR: 1.53, 95% CI: 1.05-2.25, P=0.028). However, when analyzing patients treated by primary angioplasty, the mortality was not significantly related to VF (OR: 0.86, 95% CI: 0.45-1.61, P=0.628). CONCLUSION: Our results show that VF before ICU admission was an independent predictor of in-hospital outcome in a cohort of patients in whom fibrinolysis was the most used revascularization therapy. However, this prognostic value was not found in patients treated with primary angioplasty. FAU - Medina-Rodriguez, Kristel E AU - Medina-Rodriguez KE AD - aDepartment of Cardiology, University Hospital Virgen Macarena, Sevilla bCritical Care Service, University Hospital Virgen de la Victoria, Malaga cCritical Care Unit, Hospital de Antequera dCritical Care Service, University Hospital Regional de Malaga eCritical Care Service, University Hospital Costa del Sol, Malaga fCritical Care Service, University Hospital Jerez gCritical Care Service, University Hospital Puerto Real, Cadiz hCritical Care Service, University Hospital Reina Sofia, Cordoba iCritical Care Service, University Hospital Virgen de las Nieves, Granada, Spain. FAU - Almendro-Delia, Manuel AU - Almendro-Delia M FAU - Garcia-Alcantara, Angel AU - Garcia-Alcantara A FAU - Arias-Garrido, Jose J AU - Arias-Garrido JJ FAU - Rodriguez-Yanez, Juan C AU - Rodriguez-Yanez JC FAU - Alonso-Munoz, Gemma AU - Alonso-Munoz G FAU - de la Chica-Ruiz-Ruano, Rafael AU - de la Chica-Ruiz-Ruano R FAU - Reina-Toral, Antonio AU - Reina-Toral A FAU - Varela-Lopez, Antonio AU - Varela-Lopez A FAU - Arboleda-Sanchez, Jose A AU - Arboleda-Sanchez JA FAU - Poullet-Brea, Ana M AU - Poullet-Brea AM FAU - Zaya-Ganfo, Benito AU - Zaya-Ganfo B FAU - Butron-Calderon, Michel AU - Butron-Calderon M FAU - Cristo-Ropero, Maria J AU - Cristo-Ropero MJ FAU - Hidalgo-Urbano, Rafael AU - Hidalgo-Urbano R FAU - Garcia-Rubira, Juan C AU - Garcia-Rubira JC CN - Group SCA Plataforma Ariam-Andalucia LA - eng PT - Journal Article PT - Multicenter Study PT - Observational Study PL - England TA - Coron Artery Dis JT - Coronary artery disease JID - 9011445 SB - IM MH - Aged MH - Angioplasty, Balloon, Coronary MH - Chi-Square Distribution MH - Comorbidity MH - Female MH - Hospital Mortality MH - Humans MH - Intensive Care Units MH - Logistic Models MH - Male MH - Middle Aged MH - Odds Ratio MH - Patient Admission MH - Percutaneous Coronary Intervention MH - Prevalence MH - Propensity Score MH - Registries MH - Retrospective Studies MH - Risk Factors MH - ST Elevation Myocardial Infarction/diagnosis/*epidemiology/mortality/therapy MH - Shock, Cardiogenic/epidemiology MH - Spain/epidemiology MH - Thrombolytic Therapy MH - Time Factors MH - Treatment Outcome MH - Ventricular Fibrillation/diagnosis/*epidemiology/mortality EDAT- 2017/07/21 06:00 MHDA- 2018/06/12 06:00 CRDT- 2017/07/21 06:00 PHST- 2017/07/21 06:00 [pubmed] PHST- 2018/06/12 06:00 [medline] PHST- 2017/07/21 06:00 [entrez] AID - 10.1097/MCA.0000000000000532 [doi] PST - ppublish SO - Coron Artery Dis. 2017 Nov;28(7):570-576. doi: 10.1097/MCA.0000000000000532.