PMID- 28725485
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2056-9920 (Print)
IS  - 2056-9920 (Electronic)
IS  - 2056-9920 (Linking)
VI  - 3
DP  - 2017
TI  - Segmentation errors in macular ganglion cell analysis as determined by optical 
      coherence tomography in eyes with macular pathology.
PG  - 25
LID - 10.1186/s40942-017-0078-7 [doi]
LID - 25
AB  - BACKGROUND: To evaluate artifacts in macular ganglion cell inner plexiform layer 
      (GCIPL) thickness measurement in eyes with retinal pathology using 
      spectral-domain optical coherence tomography (SD OCT). METHODS: Retrospective 
      analysis of color-coded maps, infrared images and 128 horizontal B-scans 
      (acquired in the macular ganglion cell inner plexiform layer scans), using the 
      Cirrus HD-OCT (Carl Zeiss Meditec, Dublin, CA). The study population included 105 
      eyes with various macular conditions compared to 30 eyes of 30 age-matched 
      healthy volunteers. The overall frequency of image artifacts and the relative 
      frequency of artifacts were stratified by macular disease. RESULTS: Scan errors 
      and artifacts were found in 55.1% of the 13,440 B-scans in eyes with macular 
      pathology and 26.8% of the 3840 scans in normal eyes. Segmentation errors were 
      the most common scan error in both groups, with more common involvement of both 
      segmentation borders in diseased eyes and anterior segmentation border in normal 
      eyes. CONCLUSION: Segmentation errors and artifacts in SD OCT GCA are common in 
      conditions involving the macula. These findings should be considered when 
      assessing macular GCIPL thickness and careful assessment of scans is suggested.
FAU - Alshareef, Rayan A
AU  - Alshareef RA
AD  - Department of Ophthalmology, McGill University, Montreal, QC Canada. ISNI: 0000 
      0004 1936 8649. GRID: grid.14709.3b
AD  - Department of Ophthalmology, King Abdulaziz University, Jeddah, Kingdom of Saudi 
      Arabia. ISNI: 0000 0001 0619 1117. GRID: grid.412125.1
FAU - Goud, Abhilash
AU  - Goud A
AD  - Smt. Kanuri Santhamma Retina Vitreous Centre, L. V. Prasad Eye Institute, Kallam 
      Anji Reddy Campus, Banjara Hills, Hyderabad, 500 034 India. ISNI: 0000 0004 1767 
      1636. GRID: grid.417748.9
FAU - Mikhail, Mikel
AU  - Mikhail M
AD  - Department of Ophthalmology, McGill University, Montreal, QC Canada. ISNI: 0000 
      0004 1936 8649. GRID: grid.14709.3b
FAU - Saheb, Hady
AU  - Saheb H
AD  - Department of Ophthalmology, McGill University, Montreal, QC Canada. ISNI: 0000 
      0004 1936 8649. GRID: grid.14709.3b
FAU - Peguda, Hari Kumar
AU  - Peguda HK
AD  - Smt. Kanuri Santhamma Retina Vitreous Centre, L. V. Prasad Eye Institute, Kallam 
      Anji Reddy Campus, Banjara Hills, Hyderabad, 500 034 India. ISNI: 0000 0004 1767 
      1636. GRID: grid.417748.9
FAU - Dumpala, Sunila
AU  - Dumpala S
AD  - Smt. Kanuri Santhamma Retina Vitreous Centre, L. V. Prasad Eye Institute, Kallam 
      Anji Reddy Campus, Banjara Hills, Hyderabad, 500 034 India. ISNI: 0000 0004 1767 
      1636. GRID: grid.417748.9
FAU - Rapole, Shruthi
AU  - Rapole S
AD  - Smt. Kanuri Santhamma Retina Vitreous Centre, L. V. Prasad Eye Institute, Kallam 
      Anji Reddy Campus, Banjara Hills, Hyderabad, 500 034 India. ISNI: 0000 0004 1767 
      1636. GRID: grid.417748.9
FAU - Chhablani, Jay
AU  - Chhablani J
AD  - Smt. Kanuri Santhamma Retina Vitreous Centre, L. V. Prasad Eye Institute, Kallam 
      Anji Reddy Campus, Banjara Hills, Hyderabad, 500 034 India. ISNI: 0000 0004 1767 
      1636. GRID: grid.417748.9
LA  - eng
PT  - Journal Article
DEP - 20170717
PL  - England
TA  - Int J Retina Vitreous
JT  - International journal of retina and vitreous
JID - 101677897
PMC - PMC5513039
OTO - NOTNLM
OT  - Artifacts
OT  - Errors
OT  - Ganglion cell algorithm
OT  - Ganglion cell inner plexiform layer
OT  - Spectral domain optical coherence tomography
EDAT- 2017/07/21 06:00
MHDA- 2017/07/21 06:01
PMCR- 2017/07/17
CRDT- 2017/07/21 06:00
PHST- 2017/01/14 00:00 [received]
PHST- 2017/05/02 00:00 [accepted]
PHST- 2017/07/21 06:00 [entrez]
PHST- 2017/07/21 06:00 [pubmed]
PHST- 2017/07/21 06:01 [medline]
PHST- 2017/07/17 00:00 [pmc-release]
AID - 78 [pii]
AID - 10.1186/s40942-017-0078-7 [doi]
PST - epublish
SO  - Int J Retina Vitreous. 2017 Jul 17;3:25. doi: 10.1186/s40942-017-0078-7. 
      eCollection 2017.