PMID- 28725869
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2405-8440 (Print)
IS  - 2405-8440 (Electronic)
IS  - 2405-8440 (Linking)
VI  - 3
IP  - 7
DP  - 2017 Jul
TI  - Automated approach to detecting behavioral states using EEG-DABS.
PG  - e00344
LID - 10.1016/j.heliyon.2017.e00344 [doi]
LID - e00344
AB  - Electrocorticographic (ECoG) signals represent cortical electrical dipoles 
      generated by synchronous local field potentials that result from simultaneous 
      firing of neurons at distinct frequencies (brain waves). Since different brain 
      waves correlate to different behavioral states, ECoG signals presents a novel 
      strategy to detect complex behaviors. We developed a program, EEG Detection 
      Analysis for Behavioral States (EEG-DABS) that advances Fast Fourier Transforms 
      through ECoG signals time series, separating it into (user defined) frequency 
      bands and normalizes them to reduce variability. EEG-DABS determines events if 
      segments of an experimental ECoG record have significantly different power bands 
      than a selected control pattern of EEG. Events are identified at every epoch and 
      frequency band and then are displayed as output graphs by the program. Certain 
      patterns of events correspond to specific behaviors. Once a predetermined pattern 
      was selected for a behavioral state, EEG-DABS correctly identified the desired 
      behavioral event. The selection of frequency band combinations for detection of 
      the behavior affects accuracy of the method. All instances of certain behaviors, 
      such as freezing, were correctly identified from the event patterns generated 
      with EEG-DABS. Detecting behaviors is typically achieved by visually discerning 
      unique animal phenotypes, a process that is time consuming, unreliable, and 
      subjective. EEG-DABS removes variability by using defined parameters of EEG/ECoG 
      for a desired behavior over chronic recordings. EEG-DABS presents a simple and 
      automated approach to quantify different behavioral states from ECoG signals.
FAU - Loris, Zachary B
AU  - Loris ZB
AD  - Department of Neurological Surgery, 1095 NW 14th Terrace, University of Miami 
      Miller School of Medicine, Miami, Florida, 33136, USA.
AD  - The Miami Project to Cure Paralysis, University of Miami Miller School of 
      Medicine, 1095 NW 14th Terrace, Miami, Florida, 33136, USA.
AD  - Neuroscience Program, 1120 NW 14th Street, University of Miami Miller School of 
      Medicine, Miami, Florida, 33136, USA.
FAU - Danzi, Mathew
AU  - Danzi M
AD  - The Miami Project to Cure Paralysis, University of Miami Miller School of 
      Medicine, 1095 NW 14th Terrace, Miami, Florida, 33136, USA.
AD  - Neuroscience Program, 1120 NW 14th Street, University of Miami Miller School of 
      Medicine, Miami, Florida, 33136, USA.
AD  - Center for Computational Science, University of Miami, Miami, Florida, 33146, 
      USA.
FAU - Sick, Justin
AU  - Sick J
AD  - The Miami Project to Cure Paralysis, University of Miami Miller School of 
      Medicine, 1095 NW 14th Terrace, Miami, Florida, 33136, USA.
FAU - Dietrich, W Dalton
AU  - Dietrich WD
AD  - Department of Neurological Surgery, 1095 NW 14th Terrace, University of Miami 
      Miller School of Medicine, Miami, Florida, 33136, USA.
AD  - The Miami Project to Cure Paralysis, University of Miami Miller School of 
      Medicine, 1095 NW 14th Terrace, Miami, Florida, 33136, USA.
AD  - Neuroscience Program, 1120 NW 14th Street, University of Miami Miller School of 
      Medicine, Miami, Florida, 33136, USA.
FAU - Bramlett, Helen M
AU  - Bramlett HM
AD  - Department of Neurological Surgery, 1095 NW 14th Terrace, University of Miami 
      Miller School of Medicine, Miami, Florida, 33136, USA.
AD  - The Miami Project to Cure Paralysis, University of Miami Miller School of 
      Medicine, 1095 NW 14th Terrace, Miami, Florida, 33136, USA.
AD  - Department of Neurology, 1150 NW 14th Street, University of Miami Miller School 
      of Medicine, Miami, Florida, 33136, USA.
AD  - Bruce W. Carter Department of Veterans Affairs Medical Center, 1201 NW 16th 
      Street, Miami, Florida, 33125, USA.
FAU - Sick, Thomas
AU  - Sick T
AD  - The Miami Project to Cure Paralysis, University of Miami Miller School of 
      Medicine, 1095 NW 14th Terrace, Miami, Florida, 33136, USA.
AD  - Department of Neurology, 1150 NW 14th Street, University of Miami Miller School 
      of Medicine, Miami, Florida, 33136, USA.
AD  - Neuroscience Program, 1120 NW 14th Street, University of Miami Miller School of 
      Medicine, Miami, Florida, 33136, USA.
LA  - eng
GR  - R01 NS042133/NS/NINDS NIH HHS/United States
PT  - Journal Article
DEP - 20170710
PL  - England
TA  - Heliyon
JT  - Heliyon
JID - 101672560
PMC - PMC5507012
OTO - NOTNLM
OT  - Biomedical engineering
OT  - Computer science
OT  - Medical imaging
OT  - Neurology
OT  - Neuroscience
EDAT- 2017/07/21 06:00
MHDA- 2017/07/21 06:01
PMCR- 2017/07/10
CRDT- 2017/07/21 06:00
PHST- 2017/04/15 00:00 [received]
PHST- 2017/06/05 00:00 [revised]
PHST- 2017/06/28 00:00 [accepted]
PHST- 2017/07/21 06:00 [entrez]
PHST- 2017/07/21 06:00 [pubmed]
PHST- 2017/07/21 06:01 [medline]
PHST- 2017/07/10 00:00 [pmc-release]
AID - S2405-8440(17)30638-2 [pii]
AID - e00344 [pii]
AID - 10.1016/j.heliyon.2017.e00344 [doi]
PST - epublish
SO  - Heliyon. 2017 Jul 10;3(7):e00344. doi: 10.1016/j.heliyon.2017.e00344. eCollection 
      2017 Jul.