PMID- 28736563 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20191120 IS - 1664-3828 (Print) IS - 1664-5502 (Electronic) IS - 1664-5502 (Linking) VI - 7 IP - 3 DP - 2017 Jun TI - Estimated Glomerular Filtration Rate and 6-Minute Walk Distance in African Americans with Mild to Moderate Heart Failure. PG - 227-233 LID - 10.1159/000471810 [doi] AB - BACKGROUND/AIMS: The 6-minute walk test is a measure of functional capacity in patients with heart failure (HF) or chronic kidney disease (CKD). The association between estimated glomerular filtration rate (eGFR) and 6-minute walk distance (6MWD) has not been investigated in African-Americans (AA), despite them having a higher incidence of CKD and chronic HF. Thus, our aim was to determine if eGFR was an independent predictor of 6MWD in AA >50 years of age with HF. METHODS: In this cross-sectional study, we examined the relationship between eGFR and 6MWD in 45 AA patients with HF from an urban outpatient HF clinic, using logistic regression with bootstrapping. RESULTS: The sample consisted of 53% females; mean age = 64.8 +/- 9 years, mean eGFR = 61.6 +/- 20 mL/min/1.73 m(2), and mean 6MWD = 222 +/- 78 m. A decrease in eGFR by 10 mL/min/1.73 m(2) was associated with 46% higher odds (p = 0.02) of a 6MWD