PMID- 28736762 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20210109 IS - 2469-2964 (Print) IS - 2469-2964 (Electronic) IS - 2469-2964 (Linking) VI - 2 IP - 1 DP - 2017 TI - Confusion in the Study of Immune Reconstitution Inflammatory Syndrome. PG - 126-137 LID - 10.20411/pai.v2i1.195 [doi] AB - As a consequence of late presentation for HIV care, a significant proportion of individuals develop immune reconstitution inflammatory syndrome (IRIS) soon after initiation of antiretroviral therapy. Incidence, predictors, and models of pathogenesis of IRIS vary in the literature. Here we discuss factors that may contribute to this lack of consensus. We propose that different pathogens drive different types of IRIS and suggest that these clinical conditions should be studied individually and not grouped under the general heading of "IRIS." FAU - Alvarado-de la Barrera, Claudia AU - Alvarado-de la Barrera C AD - Departamento de Investigacion en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City. FAU - Reyes-Teran, Gustavo AU - Reyes-Teran G AD - Departamento de Investigacion en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City. LA - eng GR - R01 AI118694/AI/NIAID NIH HHS/United States PT - Journal Article DEP - 20170502 PL - United States TA - Pathog Immun JT - Pathogens & immunity JID - 101683909 PMC - PMC5519094 MID - NIHMS873336 OTO - NOTNLM OT - HIV OT - IRIS OT - Kaposi's sarcoma OT - Tuberculosis COIS- POTENTIAL CONFLICTS OF INTEREST The authors do not have a conflict to declare. EDAT- 2017/07/25 06:00 MHDA- 2017/07/25 06:01 PMCR- 2017/05/02 CRDT- 2017/07/25 06:00 PHST- 2017/07/25 06:00 [entrez] PHST- 2017/07/25 06:00 [pubmed] PHST- 2017/07/25 06:01 [medline] PHST- 2017/05/02 00:00 [pmc-release] AID - pai.v2i1.195 [pii] AID - 10.20411/pai.v2i1.195 [doi] PST - ppublish SO - Pathog Immun. 2017;2(1):126-137. doi: 10.20411/pai.v2i1.195. Epub 2017 May 2.