PMID- 28750637
OWN - NLM
STAT- MEDLINE
DCOM- 20180501
LR  - 20240117
IS  - 1532-429X (Electronic)
IS  - 1097-6647 (Print)
IS  - 1097-6647 (Linking)
VI  - 19
IP  - 1
DP  - 2017 Jul 27
TI  - Quantification of myocardium at risk in ST- elevation myocardial infarction: a 
      comparison of contrast-enhanced steady-state free precession cine cardiovascular 
      magnetic resonance with coronary angiographic jeopardy scores.
PG  - 55
LID - 10.1186/s12968-017-0359-1 [doi]
LID - 55
AB  - BACKGROUND: Clinical outcome following acute myocardial infarction is predicted 
      by final infarct size evaluated in relation to left ventricular myocardium at 
      risk (MaR). Contrast-enhanced steady-state free precession (CE-SSFP) 
      cardiovascular magnetic resonance imaging (CMR) is not widely used for assessing 
      MaR. Evidence of its utility compared to traditional assessment methods and as a 
      surrogate for clinical outcome is needed. METHODS: Retrospective analysis within 
      a study evaluating post-conditioning during ST elevation myocardial infarction 
      (STEMI) treated with coronary intervention (n = 78). CE-SSFP post-infarction was 
      compared with angiographic jeopardy methods. Differences and variability between 
      CMR and angiographic methods using Bland-Altman analyses were evaluated. Clinical 
      outcomes were compared to MaR and extent of infarction. RESULTS: MaR showed 
      correlation between CE-SSFP, and both BARI and APPROACH scores of 0.83 
      (p < 0.0001) and 0.84 (p < 0.0001) respectively. Bias between CE-SSFP and BARI 
      was 1.1% (agreement limits -11.4 to +9.1). Bias between CE-SSFP and APPROACH was 
      1.2% (agreement limits -13 to +10.5). Inter-observer variability for the BARI 
      score was 0.56 +/- 2.9; 0.42 +/- 2.1 for the APPROACH score; -1.4 +/- 3.1% for CE-SSFP. 
      Intra-observer variability was 0.15 +/- 1.85 for the BARI score; for the APPROACH 
      score 0.19 +/- 1.6; and for CE-SSFP -0.58 +/- 2.9%. CONCLUSION: Quantification of MaR 
      with CE-SSFP imaging following STEMI shows high correlation and low bias compared 
      with angiographic scoring and supports its use as a reliable and practical method 
      to determine myocardial salvage in this patient population. TRIAL REGISTRATION: 
      Clinical trial registration information for the parent clinical trial: Karolinska 
      Clinical Trial Registration (2008) Unique identifier: CT20080014. Registered 
      04(th) January 2008.
FAU - De Palma, Rodney
AU  - De Palma R
AD  - Karolinska Institutet, Department of Medicine, Unit of Cardiology, Karolinska 
      University Hospital, Stockholm, Sweden. rodney_de_palma@icloud.com.
FAU - Sorensson, Peder
AU  - Sorensson P
AD  - Karolinska Institutet, Department of Medicine, Unit of Cardiology, Karolinska 
      University Hospital, Stockholm, Sweden.
FAU - Verouhis, Dinos
AU  - Verouhis D
AD  - Karolinska Institutet, Department of Medicine, Unit of Cardiology, Karolinska 
      University Hospital, Stockholm, Sweden.
FAU - Pernow, John
AU  - Pernow J
AD  - Karolinska Institutet, Department of Medicine, Unit of Cardiology, Karolinska 
      University Hospital, Stockholm, Sweden.
FAU - Saleh, Nawzad
AU  - Saleh N
AD  - Karolinska Institutet, Department of Medicine, Unit of Cardiology, Karolinska 
      University Hospital, Stockholm, Sweden.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20170727
PL  - England
TA  - J Cardiovasc Magn Reson
JT  - Journal of cardiovascular magnetic resonance : official journal of the Society 
      for Cardiovascular Magnetic Resonance
JID - 9815616
SB  - IM
MH  - Aged
MH  - *Coronary Angiography
MH  - Coronary Vessels/*diagnostic imaging/physiopathology
MH  - Female
MH  - Humans
MH  - *Magnetic Resonance Imaging, Cine
MH  - Male
MH  - Middle Aged
MH  - Observer Variation
MH  - Percutaneous Coronary Intervention
MH  - Predictive Value of Tests
MH  - Randomized Controlled Trials as Topic
MH  - Reproducibility of Results
MH  - Retrospective Studies
MH  - Risk Factors
MH  - ST Elevation Myocardial Infarction/*diagnostic imaging/physiopathology/therapy
MH  - Time Factors
MH  - Treatment Outcome
PMC - PMC5530997
OTO - NOTNLM
OT  - Myocardium
OT  - cardiovascular magnetic resonance imaging
OT  - myocardial salvage
EDAT- 2017/07/29 06:00
MHDA- 2018/05/02 06:00
PMCR- 2017/07/27
CRDT- 2017/07/29 06:00
PHST- 2016/11/29 00:00 [received]
PHST- 2017/05/03 00:00 [accepted]
PHST- 2017/07/29 06:00 [entrez]
PHST- 2017/07/29 06:00 [pubmed]
PHST- 2018/05/02 06:00 [medline]
PHST- 2017/07/27 00:00 [pmc-release]
AID - S1097-6647(23)01089-X [pii]
AID - 359 [pii]
AID - 10.1186/s12968-017-0359-1 [doi]
PST - epublish
SO  - J Cardiovasc Magn Reson. 2017 Jul 27;19(1):55. doi: 10.1186/s12968-017-0359-1.