PMID- 28751191
OWN - NLM
STAT- MEDLINE
DCOM- 20180612
LR  - 20180612
IS  - 1873-5126 (Electronic)
IS  - 1353-8020 (Linking)
VI  - 43
DP  - 2017 Oct
TI  - Minimal clinically important difference of the Modified Fatigue Impact Scale in 
      Parkinson's disease.
PG  - 101-104
LID - S1353-8020(17)30263-8 [pii]
LID - 10.1016/j.parkreldis.2017.07.016 [doi]
AB  - OBJECTIVE: Fatigue is a common and debilitating symptom of Parkinson's disease 
      (PD) with no evidence-based treatments. While several fatigue scales are 
      partially validated in PD the minimal clinically important difference (MCID) is 
      unknown for any scale but is an important psychometric value to design and 
      interpret therapeutic trials. We thus sought to determine the MCID for the 
      Modified Fatigue Impact Scale (MFIS). METHODS: This is a secondary data analysis 
      from 94 PD participants in an acupuncture trial for PD fatigue. Standard 
      psychometric approaches were used to establish validity and an anchor-based 
      approach was used to determine the MCID. RESULTS: The MFIS demonstrated good 
      concurrent validity with other outcome measures and high internal consistency. 
      MCIDs values were found to be 13.8, 6.8 and 6.2 for the MFIS total, MFIS 
      cognitive, and MFIS physical subscores respectively. CONCLUSIONS: The MFIS is a 
      valid multidimensional measure of fatigue in PD with demonstrable MCID.
CI  - Copyright (c) 2017 Elsevier Ltd. All rights reserved.
FAU - Kluger, Benzi M
AU  - Kluger BM
AD  - Department of Neurology of the University of Colorado Anschutz Medical Campus, 
      Aurora, CO, USA. Electronic address: benzi.kluger@ucdenver.edu.
FAU - Garimella, Sanjana
AU  - Garimella S
AD  - Department of Neurology of the University of Colorado Anschutz Medical Campus, 
      Aurora, CO, USA.
FAU - Garvan, Cynthia
AU  - Garvan C
AD  - Department of Anesthesia at the University of Florida, Gainesville, FL, USA.
LA  - eng
PT  - Journal Article
DEP - 20170720
PL  - England
TA  - Parkinsonism Relat Disord
JT  - Parkinsonism & related disorders
JID - 9513583
SB  - IM
MH  - Acupuncture Therapy/methods
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cognition Disorders/etiology
MH  - Disability Evaluation
MH  - Fatigue/*diagnosis/*etiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Parkinson Disease/*complications/therapy
MH  - Physical Examination
MH  - Psychometrics
MH  - Statistics as Topic
OTO - NOTNLM
OT  - Fatigue
OT  - Minimal clinically important difference
OT  - Modified Fatigue Impact Scale
OT  - Parkinson's disease
OT  - Validity
EDAT- 2017/07/29 06:00
MHDA- 2018/06/13 06:00
CRDT- 2017/07/29 06:00
PHST- 2017/06/12 00:00 [received]
PHST- 2017/07/14 00:00 [revised]
PHST- 2017/07/19 00:00 [accepted]
PHST- 2017/07/29 06:00 [pubmed]
PHST- 2018/06/13 06:00 [medline]
PHST- 2017/07/29 06:00 [entrez]
AID - S1353-8020(17)30263-8 [pii]
AID - 10.1016/j.parkreldis.2017.07.016 [doi]
PST - ppublish
SO  - Parkinsonism Relat Disord. 2017 Oct;43:101-104. doi: 
      10.1016/j.parkreldis.2017.07.016. Epub 2017 Jul 20.