PMID- 28757876 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200930 IS - 1687-9627 (Print) IS - 1687-9635 (Electronic) VI - 2017 DP - 2017 TI - A Case of Atopic Myelitis with Cervical Cavernous Angioma. PG - 9506275 LID - 10.1155/2017/9506275 [doi] LID - 9506275 AB - Atopic myelitis, a type of myelitis which appears in patients with elevated serum levels of immunoglobulin E (IgE), occurs more commonly in the cervical spinal cord, but this mechanism has not yet been elucidated. Herein, we experienced a case of atopic myelitis developed during the growth of cervical cavernous angioma caused by bleeding. A 37-year-old woman suffered from hand swelling caused by a house cat licking. At the same time when cavernous angioma had grown, she experienced a numbness in her four extremities, and multifocal peritumoral hyperintense spinal cord signals were seen. The diagnosis of atopic myelitis was made because we observed significantly elevated levels of specific IgE antibody to cat dander. Symptoms disappeared immediately after steroid pulse therapy. We subsequently resected a cavernous angioma, and eosinophil invasion was found inside it. This is the first case report of atopic myelitis which developed in association with spinal cord vascular lesions. A local blood-brain barrier breakdown due to hemorrhagic lesions of the spinal cord may have contributed to the onset of atopic myelitis. FAU - Fukuda, Miyuki AU - Fukuda M AUID- ORCID: 0000-0002-2849-2700 AD - Shin-Aikai Spine Center, Katano Hospital, Matsuzuka 39-1, Katano City, Osaka 576-0043, Japan. FAU - Manabe, Hiroaki AU - Manabe H AD - Shin-Aikai Spine Center, Katano Hospital, Matsuzuka 39-1, Katano City, Osaka 576-0043, Japan. FAU - Sasaki, Nobuhiro AU - Sasaki N AD - Shin-Aikai Spine Center, Katano Hospital, Matsuzuka 39-1, Katano City, Osaka 576-0043, Japan. FAU - Kuroda, Masayuki AU - Kuroda M AD - Shin-Aikai Spine Center, Katano Hospital, Matsuzuka 39-1, Katano City, Osaka 576-0043, Japan. FAU - Hoshimaru, Minoru AU - Hoshimaru M AD - Shin-Aikai Spine Center, Katano Hospital, Matsuzuka 39-1, Katano City, Osaka 576-0043, Japan. FAU - Ueda, Shigeo AU - Ueda S AUID- ORCID: 0000-0003-4037-1247 AD - Shin-Aikai Spine Center, Katano Hospital, Matsuzuka 39-1, Katano City, Osaka 576-0043, Japan. LA - eng PT - Case Reports DEP - 20170703 PL - United States TA - Case Rep Med JT - Case reports in medicine JID - 101512910 PMC - PMC5512020 EDAT- 2017/08/02 06:00 MHDA- 2017/08/02 06:01 PMCR- 2017/07/03 CRDT- 2017/08/01 06:00 PHST- 2017/03/10 00:00 [received] PHST- 2017/06/01 00:00 [accepted] PHST- 2017/08/01 06:00 [entrez] PHST- 2017/08/02 06:00 [pubmed] PHST- 2017/08/02 06:01 [medline] PHST- 2017/07/03 00:00 [pmc-release] AID - 10.1155/2017/9506275 [doi] PST - ppublish SO - Case Rep Med. 2017;2017:9506275. doi: 10.1155/2017/9506275. Epub 2017 Jul 3.